Search Results - "Appleton JA"

Aspartic protease 2 from Trichinella spiralis excretion/secretion products hydrolyzes tight junctions of intestinal epithelial cells.

Authors: Long, Shao Rong Zhang, Hui Ran Wang, Jing Jing et al.

Source: PLoS Neglected Tropical Diseases. 12/8/2025, Vol. 19 Issue 12, p1-23. 23p.

Vaccination of mice with Trichinella spiralis serine proteinase enhanced gut epithelial barrier and elicited a high protective immunity.

Authors: Wu, Jin Yi Zhang, Xin Zhuo Zhang, Ru et al.

Source: PLoS Neglected Tropical Diseases. 3/24/2026, Vol. 20 Issue 3, p1-27. 27p.

A Trichinella spiralis serine protease triggers gut epithelial apoptosis and destroys the barrier integrity to mediate larval invasion.

Authors: Lu, Qi Qi Zhang, Xin Zhuo Cong, Pei Kun et al.

Source: PLoS Neglected Tropical Diseases. 10/30/2025, Vol. 19 Issue 10, p1-26. 26p.

Transcriptional signatures in human macrophage-like cells infected by Leishmania infantum, Leishmania major and Leishmania tropica.

Authors: Diotallevi, Aurora Bruno, Federica Castelli, Germano et al.

Source: PLoS Neglected Tropical Diseases. 4/5/2024, Vol. 18 Issue 4, p1-24. 24p.

Helminth infection driven gastrointestinal hypermotility is independent of eosinophils and mediated by alterations in smooth muscle instead of enteric neurons.

Authors: Wang, Haozhe Barry, Kristian Zaini, Aidil et al.

Source: PLoS Pathogens. 8/14/2024, Vol. 20 Issue 8, p1-26. 26p.

Vaccination of mice with Trichinella spiralis C-type lectin elicited the protective immunity and enhanced gut epithelial barrier function.

Authors: Wang, Bo Ning Zhang, Xin Zhuo Wu, Jin Yi et al.

Source: PLoS Neglected Tropical Diseases. 1/22/2025, Vol. 19 Issue 1, p1-26. 26p.

Enteric tuft cells coordinate timely expulsion of the tapeworm Hymenolepis diminuta from the murine host by coordinating local but not systemic immunity.

Authors: Rajeev, Sruthi Li, ShuHua Leon-Coria, Aralia et al.

Source: PLoS Pathogens. 7/31/2024, Vol. 20 Issue 7, p1-32. 32p.

In vitro knockdown of TsDNase II-7 suppresses Trichinella spiralis invasion into the host's intestinal epithelial cells.

Authors: Wang, Jing Jin, Xuemin Li, Chengyao et al.

Source: PLoS Neglected Tropical Diseases. 6/8/2023, Vol. 16 Issue 6, p1-18. 18p.

Metabolically reprogrammed eosinophils impair T cell immunity and cause chronic skin infection.

Authors: Barinberg D Sebald H Gold T et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2026 Apr; Vol. 18 (4), pp. 1292-1317. Date of Electronic Publication: 2026 Mar 11.

Publication Type: Journal Article

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

MicroRNA-194 regulates parasitic load and IL-1β-dependent nitric oxide production in the peripheral blood mononuclear cells of dogs with leishmaniasis.

Authors: Costa, Sidnei Ferro Soares, Matheus Fujimura Poleto Bragato, Jaqueline et al.

Source: PLoS Neglected Tropical Diseases. 1/19/2024, Vol. 18 Issue 1, p1-22. 22p.

A novel Trichinella spiralis serine proteinase disrupted gut epithelial barrier and mediated larval invasion through binding to RACK1 and activating MAPK/ERK1/2 pathway.

Authors: Song, Yan Yan Zhang, Xin Zhuo Wang, Bo Ning et al.

Source: PLoS Neglected Tropical Diseases. 1/8/2024, Vol. 18 Issue 1, p1-37. 37p.

Vaccination with novel low-molecular weight proteins secreted from Trichinella spiralis inhibits establishment of infection.

Authors: Srey, Mellina T. Taccogna, Alessia Oksov, Yelena et al.

Source: PLoS Neglected Tropical Diseases. 11/18/2020, Vol. 14 Issue 11, p1-19. 19p.

Marine Biotoxins as Potential Nematocide: Impact of Cassiopea andromeda Venom Against Acute and Chronic Trichinellosis in Murine model.

Authors: Elmahy RA Salama AM Radwan NA et al.

Source: Acta parasitologica [Acta Parasitol] 2026 Apr 06; Vol. 71 (2). Date of Electronic Publication: 2026 Apr 06.

Publication Type: Journal Article

Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 9301947 Publication Model: Electronic Cited Medium: Internet ISSN: 1896-1851 (Electronic) Linking ISSN: 12302821 NLM ISO Abbreviation: Acta Parasitol Subsets: MEDLINE

Targeting soluble amyloid-beta oligomers with a novel nanobody.

Authors: Haynes, Justin R. Whitmore, Clayton A. Behof, William J. et al.

Source: Scientific Reports. 7/11/2024, Vol. 14 Issue 1, p1-13. 13p.

Oral vaccination of mice with attenuated Salmonella encoding Trichinella spiralis calreticulin and serine protease 1.1 confers protective immunity in BALB/c mice.

Authors: Bai, Sheng Jie Han, Lu Lu Liu, Ruo Dan et al.

Source: PLoS Neglected Tropical Diseases. 11/29/2022, Vol. 16 Issue 11, p1-28. 28p.

Recombinant CsHscB of carcinogenic liver fluke Clonorchis sinensis induces IL-10 production by binding with TLR2.

Authors: Yan, Chao Fang, Fan Zhang, Yu-Zhao et al.

Source: PLoS Neglected Tropical Diseases. 10/12/2020, Vol. 14 Issue 10, p1-17. 17p.

Lentinan improved the efficacy of vaccine against Trichinella spiralis in an NLRP3 dependent manner.

Authors: Jin, Xuemin Liu, Xiaolei Ding, Jing et al.

Source: PLoS Neglected Tropical Diseases. 9/25/2020, Vol. 14 Issue 9, p1-13. 13p.

Characterization of a novel pyruvate kinase from Trichinella spiralis and its participation in sugar metabolism, larval molting and development.

Authors: Yue, Wen Wen Yan, Shu Wei Zhang, Ru et al.

Source: PLoS Neglected Tropical Diseases. 10/31/2022, Vol. 16 Issue 10, p1-28. 28p.

Bat cellular immunity varies by year and dietary habit amidst land conversion.

Authors: DeAnglis, Isabella K Andrews, Benjamin R Lock, Lauren R et al.

Source: Conservation Physiology. 2024, Vol. 12 Issue 1, p1-14. 14p.

Effect of mast cell stabilization on angiogenesis in primary and secondary experimental Trichinella spiralis infection.

Authors: EL-Dardiry, Marwa A. Abdel-Aal, Amany A. Abdeltawab, Magda S. A. et al.

Source: Parasites & Vectors. 11/6/2021, Vol. 14 Issue 1, p1-13. 13p.