Search Results - "Auclair, Adam"

Absorption, Metabolism, Distribution and Excretion (ADME) and Absolute Bioavailability Assessment of Zongertinib in Healthy Male Volunteers.

Authors: Grempler, Rolf Joseph, David Gan, Guanfa et al.

Source: Clinical Drug Investigation. Feb2026, Vol. 46 Issue 2, p115-125.

An 'Omics Approach to Unraveling the Paradoxical Effect of Diet on Perfluorooctanesulfonic Acid (PFOS) and Perfluorononanoic Acid (PFNA)-Induced Hepatic Steatosis.

Authors: Pfohl, Marisa Marques, Emily Auclair, Adam et al.

Source: Toxicological Sciences. Apr2021, Vol. 180 Issue 2, p277-294. 18p.

Fenofibrate Downregulates NF-κB Signaling to Inhibit Pro-inflammatory Cytokine Secretion in Human THP-1 Macrophages and During Primary Biliary Cholangitis.

Authors: Gallucci, Gina M. Alsuwayt, Bader Auclair, Adam M. et al.

Source: Inflammation. Dec2022, Vol. 45 Issue 6, p2570-2581. 12p.

Perfluorooctanesulfonic Acid and Perfluorohexanesulfonic Acid Alter the Blood Lipidome and the Hepatic Proteome in a Murine Model of Diet-Induced Obesity.

Authors: Pfohl, Marisa Ingram, Lishann Marques, Emily et al.

Source: Toxicological Sciences. Dec2020, Vol. 178 Issue 2, p311-324. 14p.

The Current State of Biotransformation Science – Industry Survey of In Vitro and In Vivo Practices, Clinical Translation, and Future Trends.

Authors: Savaryn, John P. Coe, Kevin Cerny, Matthew A. et al.

Source: Pharmaceutical Research. Nov2024, Vol. 41 Issue 11, p2079-2093. 15p.

Perfluorooctanesulfonic acid (PFOS) administration shifts the hepatic proteome and augments dietary outcomes related to hepatic steatosis in mice.

Authors: Marques, Emily Pfohl, Marisa Auclair, Adam et al.

Source: Toxicology & Applied Pharmacology. Dec2020, Vol. 408, pN.PAG-N.PAG. 1p.

Guided Sample Pooling in Human Mass Balance Studies: A Recommended Strategic Decision Framework.

Authors: Cuyckens F Li W Auclair AM et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2026 Mar; Vol. 119 (3), pp. 591-597. Date of Electronic Publication: 2025 Dec 17.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Mass balance and absolute bioavailability of avenciguat (¹⁴C) after intravenous or oral administration in healthy male participants.

Authors: Joseph D Wong D Mitra P et al.

Source: Expert opinion on investigational drugs [Expert Opin Investig Drugs] 2026 Jan; Vol. 35 (1), pp. 75-84. Date of Electronic Publication: 2026 Jan 13.

Publication Type: Journal Article; Clinical Trial, Phase I

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9434197 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7658 (Electronic) Linking ISSN: 13543784 NLM ISO Abbreviation: Expert Opin Investig Drugs Subsets: MEDLINE

Fenofibrate Improves Liver Function and Reduces the Toxicity of the Bile Acid Pool in Patients With Primary Biliary Cholangitis and Primary Sclerosing Cholangitis Who Are Partial Responders to Ursodiol.

Authors: Ghonem NS Auclair AM Hemme CL et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2020 Dec; Vol. 108 (6), pp. 1213-1223. Date of Electronic Publication: 2020 Jul 17.

Publication Type: Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE