Search Results - "Backer JM"

SH3 domains selectively activate the PI3 kinase through non-conventional tertiary contacts.

Authors: Aljedani SS Sandholu A Aldehaiman A et al.

Source: Communications biology [Commun Biol] 2026 Jan 19; Vol. 9 (1). Date of Electronic Publication: 2026 Jan 19.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Macropinocytosis: mechanisms and regulation.

Authors: Salloum G Bresnick AR Backer JM

Source: The Biochemical journal [Biochem J] 2023 Mar 15; Vol. 480 (5), pp. 335-362.

Publication Type: Review; Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

PIP3 abundance overcomes PI3K signaling selectivity in invadopodia.

Authors: Jakubik CT Weckerly CC Hammond GRV et al.

Source: FEBS letters [FEBS Lett] 2022 Feb; Vol. 596 (4), pp. 417-426. Date of Electronic Publication: 2022 Jan 12.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3468 (Electronic) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE

Platelet PI3Kβ regulates breast cancer metastasis.

Authors: Graff RC Haimowitz A Aguilan JT et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 14. Date of Electronic Publication: 2024 Sep 14.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Imaging Early-Stage Metastases Using an ¹⁸F-Labeled VEGFR-1-Specific Single Chain VEGF Mutant.

Authors: Mason CA Carter LM Mandleywala K et al.

Source: Molecular imaging and biology [Mol Imaging Biol] 2021 Jun; Vol. 23 (3), pp. 340-349. Date of Electronic Publication: 2020 Nov 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101125610 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-2002 (Electronic) Linking ISSN: 15361632 NLM ISO Abbreviation: Mol Imaging Biol Subsets: MEDLINE

PI3Kβ-A Versatile Transducer for GPCR, RTK, and Small GTPase Signaling.

Authors: Bresnick AR Backer JM

Source: Endocrinology [Endocrinology] 2019 Mar 01; Vol. 160 (3), pp. 536-555.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

Selective Imaging of Vascular Endothelial Growth Factor Receptor-1 and Receptor-2 in Atherosclerotic Lesions in Diabetic and Non-diabetic ApoE^-/- Mice.

Authors: Tekabe Y Johnson LL Rodriquez K et al.

Source: Molecular imaging and biology [Mol Imaging Biol] 2018 Feb; Vol. 20 (1), pp. 85-93.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101125610 Publication Model: Print Cited Medium: Internet ISSN: 1860-2002 (Electronic) Linking ISSN: 15361632 NLM ISO Abbreviation: Mol Imaging Biol Subsets: MEDLINE

Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism.

Authors: Bilanges B Alliouachene S Pearce W et al.

Source: Nature communications [Nat Commun] 2017 Nov 27; Vol. 8 (1), pp. 1804. Date of Electronic Publication: 2017 Nov 27.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.

Authors: Erami Z Khalil BD Salloum G et al.

Source: The Biochemical journal [Biochem J] 2017 Nov 16; Vol. 474 (23), pp. 3903-3914. Date of Electronic Publication: 2017 Nov 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Electronic Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

Selective Imaging of VEGFR-1 and VEGFR-2 Using 89Zr-Labeled Single-Chain VEGF Mutants.

Authors: Meyer JP Edwards KJ Kozlowski P et al.

Source: Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2016 Nov; Vol. 57 (11), pp. 1811-1816. Date of Electronic Publication: 2016 Jul 07.

Publication Type: Journal Article

Journal Info: Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE

Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells.

Authors: Houslay DM Anderson KE Chessa T et al.

Source: Science signaling [Sci Signal] 2016 Aug 16; Vol. 9 (441), pp. ra82. Date of Electronic Publication: 2016 Aug 16.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

The intricate regulation and complex functions of the Class III phosphoinositide 3-kinase Vps34.

Authors: Backer JM; Departments of Molecular Pharmacology and Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, U.S.A. jonathan.backer@einstein.yu.edu.

Source: The Biochemical journal [Biochem J] 2016 Aug 01; Vol. 473 (15), pp. 2251-71.

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural

Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Authors: Klionsky DJ Abdelmohsen K Abe A et al.

Source: Autophagy [Autophagy] 2016; Vol. 12 (1), pp. 1-222.

Publication Type: Guideline; Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE

Noninvasive Imaging of Liposomal Delivery of Superparamagnetic Iron Oxide Nanoparticles to Orthotopic Human Breast Tumor in Mice.

Authors: Kato Y Zhu W Backer MV et al.

Source: Pharmaceutical research [Pharm Res] 2015 Nov; Vol. 32 (11), pp. 3746-3755. Date of Electronic Publication: 2015 Jun 16.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE

Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract.

Authors: Maddala R Gao J Mathias RT et al.

Source: Scientific reports [Sci Rep] 2021 Jan 26; Vol. 11 (1), pp. 2203. Date of Electronic Publication: 2021 Jan 26.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling.

Authors: Braccini L Ciraolo E Campa CC et al.

Source: Nature communications [Nat Commun] 2015 Jun 23; Vol. 6, pp. 7400. Date of Electronic Publication: 2015 Jun 23.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Suppression of mTORC1 activation in acid-α-glucosidase-deficient cells and mice is ameliorated by leucine supplementation.

Authors: Shemesh A Wang Y Yang Y et al.

Source: American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2014 Nov 15; Vol. 307 (10), pp. R1251-9. Date of Electronic Publication: 2014 Sep 17.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1490 (Electronic) Linking ISSN: 03636119 NLM ISO Abbreviation: Am J Physiol Regul Integr Comp Physiol Subsets: MEDLINE

NRBF2 regulates macroautophagy as a component of Vps34 Complex I.

Authors: Cao Y Wang Y Abi Saab WF et al.

Source: The Biochemical journal [Biochem J] 2014 Jul 15; Vol. 461 (2), pp. 315-22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

Phosphatidylinositol-3,4,5-trisphosphate: tool of choice for class I PI 3-kinases.

Authors: Salamon RS Backer JM

Source: BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2013 Jul; Vol. 35 (7), pp. 602-11.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 8510851 Publication Model: Print Cited Medium: Internet ISSN: 1521-1878 (Electronic) Linking ISSN: 02659247 NLM ISO Abbreviation: Bioessays Subsets: MEDLINE

Characterization of a tumor-associated activating mutation of the p110β PI 3-kinase.

Authors: Dbouk HA Khalil BD Wu H et al.

Source: PloS one [PLoS One] 2013 May 29; Vol. 8 (5), pp. e63833. Date of Electronic Publication: 2013 May 29 (Print Publication: 2013).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE