Search Results - "Backer JM"

HIV-1 Vpr is targeted for degradation by autophagy.

Authors: Chen, Yuexuan Klute, Susanne Bansal, Anju et al.

Source: PLoS Pathogens. 3/2/2026, Vol. 22 Issue 3, p1-35. 35p.

Dynamic interplay of autophagy and membrane repair during Mycobacterium tuberculosis Infection.

Authors: Augenstreich, Jacques Phan, Anna T. Allen, Charles N. S. et al.

Source: PLoS Pathogens. 1/2/2025, Vol. 21 Issue 1, p1-31. 31p.

SH3 domains selectively activate the PI3 kinase through non-conventional tertiary contacts.

Authors: Aljedani SS Sandholu A Aldehaiman A et al.

Source: Communications biology [Commun Biol] 2026 Jan 19; Vol. 9 (1). Date of Electronic Publication: 2026 Jan 19.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE

Aβ25-35-induced autophagy and apoptosis are prevented by the CRMP2-derived peptide ST2-104 (R9-CBD3) via a CaMKKβ/AMPK/mTOR signaling hub.

Authors: Ji, Yingshi Ren, Jinghong Qian, Yuan et al.

Source: PLoS ONE. 9/26/2024, Vol. 19 Issue 9, p1-19. 19p.

CUL5 E3 ubiquitin ligase regulates the evasion of bladder cancer cells to CD8⁺ T cell-mediated killing by inhibiting autophagy.

Authors: Gao, Xincheng Yu, Yanchao Sun, Jiayin et al.

Source: PLoS Biology. 2/9/2026, Vol. 24 Issue 2, p1-22. 22p.

PI3K/AKT signaling in parasites and parasite diseases: Role and therapeutic potential.

Authors: Yan, Lujun Li, Yating Yang, Xing et al.

Source: Virulence. Dec2025, Vol. 16 Issue 1, p1-17. 17p.

High-fat diet impairs intermediate-term memory by autophagic-lysosomal dysfunction in Drosophila.

Authors: Yue, Tong Jiang, Minrui Onuki, Kotomi et al.

Source: PLoS Genetics. 8/18/2025, Vol. 21 Issue 8, p1-24. 24p.

Understanding the conformational dynamics of PI3Kα due to helical domain mutations: insights from Markov state model analysis.

Authors: Jani V Sonavane U Sawant S

Source: Molecular diversity [Mol Divers] 2025 Dec; Vol. 29 (6), pp. 6179-6203. Date of Electronic Publication: 2025 Feb 21.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

Organelle landscape analysis using a multiparametric particle-based method.

Authors: Kurikawa, Yoshitaka Koyama-Honda, Ikuko Tamura, Norito et al.

Source: PLoS Biology. 9/17/2024, Vol. 22 Issue 9, p1-22. 22p.

Subareolar sclerosing ductal hyperplasia shows PI3K pathway alterations.

Authors: Boyraz, Baris Robinson, Brian Lindeman, Neal et al.

Source: Histopathology. Mar2025, Vol. 86 Issue 5, p824-827. 4p.

Endosomal microautophagy is activated by specific cellular stresses in trout hepatocytes.

Authors: Vélez, Emilio J. Véron, Vincent Gouis, Jeanne et al.

Source: Scientific Reports. 11/10/2025, Vol. 15 Issue 1, p1-12. 12p.

Therapeutic role of gut microbial metabolite indole propionic acid in a rat model of high-fat diet/Streptozotocin-Induced diabetes: enhancing glucose metabolism, antioxidant defense and PI3K/Akt/GLUT4 signaling pathway.

Authors: Shuja N Tarique I Sohail S et al.

Source: Acta diabetologica [Acta Diabetol] 2026 Jul; Vol. 63 (7), pp. 1179-1187. Date of Electronic Publication: 2026 Feb 18.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9200299 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-5233 (Electronic) Linking ISSN: 09405429 NLM ISO Abbreviation: Acta Diabetol Subsets: MEDLINE

The role of SUMOylation in epithelial-mesenchymal transition.

Authors: Li S Yu X Liang L et al.

Source: Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2025 Sep; Vol. 103 (9), pp. 1005-1018. Date of Electronic Publication: 2025 Jul 04.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 9504370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1440 (Electronic) Linking ISSN: 09462716 NLM ISO Abbreviation: J Mol Med (Berl) Subsets: MEDLINE

PIK-III exerts anti-fibrotic effects in activated fibroblasts by regulating p38 activation.

Authors: Sanchez, Santiago McDowell-Sanchez, Aaron K. Al-Meerani, Sharaz B. et al.

Source: PLoS ONE. 9/6/2024, Vol. 19 Issue 9, p1-13. 13p.

ER-driven Contact Sites in Autophagosome Biogenesis Sequence.

Authors: Da Graça, Juliane Amiri Czajkowski, Dobrawa Morel, Etienne

Source: Contact (25152564). 5/11/2026, Vol. 9, p1-12. 12p.

A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in Drosophila secondary cells.

Authors: Wells, Adam Mendes, Cláudia C. Castellanos, Felix et al.

Source: PLoS Genetics. 10/16/2023, Vol. 19 Issue 10, p1-33. 33p.

Genome-wide CRISPR/Cas9 screen identifies SLC39A9 and PIK3C3 as crucial entry factors for Ebola virus infection.

Authors: Gong, Mingli Peng, Cheng Yang, Chen et al.

Source: PLoS Pathogens. 8/22/2024, Vol. 20 Issue 8, p1-30. 30p.

Restoration of lysosomal membrane integrity in cell models of Pompe disease depends on fatty acid synthase and its product palmitic acid.

Authors: Le Guillou E Segaloni A Gadault A et al.

Source: Cellular & molecular biology letters [Cell Mol Biol Lett] 2026 Apr 09; Vol. 31 (1). Date of Electronic Publication: 2026 Apr 09.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell Mol Biol Lett Subsets: MEDLINE

Allosteric modulation of Grb2 drives ligand-dependent signal responses.

Authors: Di Felice, Mariana Rolfi, Lucrezia Romana Toso, Julian et al.

Source: Biology Direct. 5/23/2025, Vol. 20 Issue 1, p1-13. 13p.

Pi4ka downregulation triggers Creb3l2-dependent lysosomal dysfunction to promote maladaptive tubular remodeling and immune activation in acute kidney injury.

Authors: Chen Z Xie J Wu C et al.

Source: Cell death & disease [Cell Death Dis] 2026 Apr 27; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 27.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE