Search Results - "Barbash O"

Phosphorylation-dependent regulation of SCF^Fbx4 dimerization and activity involves a novel component, 14-3-3ɛ.

Authors: Barbash, O Lee, E K Diehl, J A

Source: Oncogene. 4/28/2011, Vol. 30 Issue 17, p1995-2002. 8p. 1 Color Photograph, 2 Diagrams, 2 Graphs.

Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF^{Fbx4/αB-crystallin} ligase and subsequent proteasome-dependent degradation.

Authors: Barbash, O. Egan, E. Pontano, L. L. et al.

Source: Oncogene. 12/10/2009, Vol. 28 Issue 49, p4317-4325. 9p. 3 Black and White Photographs, 2 Graphs.

Phase Ib and dose-expansion study of GSK3326595, a PRMT5 inhibitor as monotherapy and in combination with pembrolizumab in patients with advanced cancers.

Authors: Gounder, M.M. Martin-Romano, P. Italiano, A. et al.

Source: Annals of Oncology. Dec2025, Vol. 36 Issue 12, p1480-1491. 12p.

Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1.

Authors: Benzeno, S. Lu, F. Guo, M. et al.

Source: Oncogene. 10/12/2006, Vol. 25 Issue 47, p6291-6303. 13p. 8 Graphs.

456MO METEOR-1: A phase I study of the safety and efficacy of the protein arginine methyltransferase 5 (PRMT5) inhibitor GSK3326595 in advanced solid tumors.

Authors: Postel-Vinay, S. Italiano, A. Martin Romano, P. et al.

Source: Annals of Oncology. 2022 Supplement 7, Vol. 33, pS746-S747. 2p.

Editorial Expression of Concern: Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1.

Authors: Benzeno S Lu F Guo M et al.

Source: Oncogene [Oncogene] 2026 Jul; Vol. 45 (27), pp. 2775.

Publication Type: Expression of Concern

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE; In Process

Phase I/II study of the clinical activity and safety of GSK3326595 in patients with myeloid neoplasms.

Authors: Watts J Minden MD Bachiashvili K et al.

Source: Therapeutic advances in hematology [Ther Adv Hematol] 2024 Sep 14; Vol. 15, pp. 20406207241275376. Date of Electronic Publication: 2024 Sep 14 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Sage Country of Publication: England NLM ID: 101549589 Publication Model: eCollection Cited Medium: Print ISSN: 2040-6207 (Print) Linking ISSN: 20406207 NLM ISO Abbreviation: Ther Adv Hematol Subsets: PubMed not MEDLINE

Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 coactivation.

Authors: Shah V Giotopoulos G Osaki H et al.

Source: Blood [Blood] 2025 Feb 13; Vol. 145 (7), pp. 748-764.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

Potential Synergistic Effect between Niraparib and Statins in Ovarian Cancer Clinical Trials.

Authors: Zhang H Rutkowska A González-Martín A et al.

Source: Cancer research communications [Cancer Res Commun] 2025 Jan 01; Vol. 5 (1), pp. 178-186.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE

TP53 mutations and RNA-binding protein MUSASHI-2 drive resistance to PRMT5-targeted therapy in B-cell lymphoma.

Authors: Erazo T Evans CM Zakheim D et al.

Source: Nature communications [Nat Commun] 2022 Sep 27; Vol. 13 (1), pp. 5676. Date of Electronic Publication: 2022 Sep 27.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Homologous Recombination Deficiency: Concepts, Definitions, and Assays.

Authors: Stewart MD Merino Vega D Arend RC et al.

Source: The oncologist [Oncologist] 2022 Mar 11; Vol. 27 (3), pp. 167-174.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE

A Phase I/II Study of GSK525762 Combined with Fulvestrant in Patients with Hormone Receptor-positive/HER2-negative Advanced or Metastatic Breast Cancer.

Authors: Cescon DW Hilton J Morales Murilo S et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Jan 17; Vol. 30 (2), pp. 334-343.

Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Limited antitumor activity of combined BET and MEK inhibition in neuroblastoma.

Authors: Healy JR Hart LS Shazad AL et al.

Source: Pediatric blood & cancer [Pediatr Blood Cancer] 2020 Jun; Vol. 67 (6), pp. e28267. Date of Electronic Publication: 2020 Apr 19.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE

Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors.

Authors: Piha-Paul SA Hann CL French CA et al.

Source: JNCI cancer spectrum [JNCI Cancer Spectr] 2019 Nov 06; Vol. 4 (2), pp. pkz093. Date of Electronic Publication: 2019 Nov 06 (Print Publication: 2020).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101721827 Publication Model: eCollection Cited Medium: Internet ISSN: 2515-5091 (Electronic) Linking ISSN: 25155091 NLM ISO Abbreviation: JNCI Cancer Spectr Subsets: PubMed not MEDLINE

A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies.

Authors: Dawson MA Borthakur G Huntly BJP et al.

Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2023 Feb 16; Vol. 29 (4), pp. 711-722.

Publication Type: Clinical Trial, Phase II; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia.

Authors: Bell CC Fennell KA Chan YC et al.

Source: Nature communications [Nat Commun] 2019 Jun 20; Vol. 10 (1), pp. 2723. Date of Electronic Publication: 2019 Jun 20.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses.

Authors: Fedoriw A Shi L O'Brien S et al.

Source: Cancer immunology research [Cancer Immunol Res] 2022 Apr 01; Vol. 10 (4), pp. 420-436.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE

A Chemical Acetylation-Based Mass Spectrometry Platform for Histone Methylation Profiling.

Authors: Zappacosta F Wagner CD Della Pietra A 3rd et al.

Source: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2021; Vol. 20, pp. 100067. Date of Electronic Publication: 2021 Mar 26.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 101125647 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-9484 (Electronic) Linking ISSN: 15359476 NLM ISO Abbreviation: Mol Cell Proteomics Subsets: MEDLINE

A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.

Authors: Chan-Penebre E Kuplast KG Majer CR et al.

Source: Nature chemical biology [Nat Chem Biol] 2015 Jun; Vol. 11 (6), pp. 432-7. Date of Electronic Publication: 2015 Apr 27.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.

Authors: Mazur PK Reynoird N Khatri P et al.

Source: Nature [Nature] 2014 Jun 12; Vol. 510 (7504), pp. 283-7. Date of Electronic Publication: 2014 May 21.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE