Search Results - "Botros SS"

Early intervention with probiotics and metformin alleviates liver injury in NAFLD rats via targeting gut microbiota dysbiosis and p-AKT/mTOR/LC-3II pathways.

Authors: Seif el-Din, Sayed H Salem, MB El-Lakkany, NM et al.

Source: Human & Experimental Toxicology. Sep2021, Vol. 40 Issue 9, p1496-1509. 14p.

Chemical profile and in vitro antischistosomal activity of Crotalaria madurensis different extracts.

Authors: Mohamed MA William S Ghareeb MA et al.

Source: Scientific reports [Sci Rep] 2026 Jul 10; Vol. 16 (1). Date of Electronic Publication: 2026 Jul 10.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

The antifibrotic effect of Vildagliptin and Diaminodiphenyl Sulfone in murine schistosomiasis mansoni.

Authors: Hendawy AS Sabra AA George MY et al.

Source: Scientific reports [Sci Rep] 2025 Mar 24; Vol. 15 (1), pp. 10084. Date of Electronic Publication: 2025 Mar 24.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Deciphering the enzymatic target of a new family of antischistosomal agents bearing a quinazoline scaffold using complementary computational tools.

Authors: Sebastian-Perez V García-Rubia A Seif El-Din SH et al.

Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 511-523.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE

Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages.

Authors: Munday JC Kunz S Kalejaiye TD et al.

Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Jul 30; Vol. 14 (7), pp. e0008447. Date of Electronic Publication: 2020 Jul 30 (Print Publication: 2020).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?

Authors: Zheng Y Schroeder S Kanev GK et al.

Source: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 06; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 06.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

Vildagliptin alleviates liver fibrosis in NASH diabetic rats via modulation of insulin resistance, oxidative stress, and inflammatory cascades.

Authors: Hendawy AS El-Lakkany NM Mantawy EM et al.

Source: Life sciences [Life Sci] 2022 Sep 01; Vol. 304, pp. 120695. Date of Electronic Publication: 2022 Jun 04.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE

Metabolic profile and hepatoprotective activity of the anthocyanin-rich extract of Hibiscus sabdariffa calyces.

Authors: Ezzat SM Salama MM Seif El-Din SH et al.

Source: Pharmaceutical biology [Pharm Biol] 2016 Dec; Vol. 54 (12), pp. 3172-3181. Date of Electronic Publication: 2016 Aug 26.

Publication Type: Journal Article

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5116 (Electronic) Linking ISSN: 13880209 NLM ISO Abbreviation: Pharm Biol Subsets: MEDLINE

Bioavailability of paracetamol with/without caffeine in Egyptian patients with hepatitis C virus.

Authors: El-Lakkany NM Hendawy AS Seif El-Din SH et al.

Source: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2016 May; Vol. 72 (5), pp. 573-82. Date of Electronic Publication: 2016 Feb 18.

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 1256165 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1041 (Electronic) Linking ISSN: 00316970 NLM ISO Abbreviation: Eur J Clin Pharmacol Subsets: MEDLINE

Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways.

Authors: Ahmed LA Salem MB Seif El-Din SH et al.

Source: European journal of pharmacology [Eur J Pharmacol] 2020 Nov 15; Vol. 887, pp. 173461. Date of Electronic Publication: 2020 Aug 03.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

Potential effect of the medicinal plants Calotropis procera, Ficus elastica and Zingiber officinale against Schistosoma mansoni in mice.

Authors: Seif el-Din SH El-Lakkany NM Mohamed MA et al.

Source: Pharmaceutical biology [Pharm Biol] 2014 Feb; Vol. 52 (2), pp. 144-50. Date of Electronic Publication: 2013 Sep 19.

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-5116 (Electronic) Linking ISSN: 13880209 NLM ISO Abbreviation: Pharm Biol Subsets: MEDLINE

The phosphodiesterase-4 inhibitor roflumilast impacts Schistosoma mansoni ovipositing in vitro but displays only modest antischistosomal activity in vivo.

Authors: Botros SS El-Lakkany NM Seif El-Din SH et al.

Source: Experimental parasitology [Exp Parasitol] 2020 Jan; Vol. 208, pp. 107793. Date of Electronic Publication: 2019 Nov 08.

Publication Type: Journal Article

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0370713 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2449 (Electronic) Linking ISSN: 00144894 NLM ISO Abbreviation: Exp Parasitol Subsets: MEDLINE

Praziquantel efficacy in mice infected with PZQ non-susceptible S. mansoni isolate treated with artemether: parasitological, biochemical and immunohistochemical assessment.

Authors: Botros SS Hammam O Mahmoud M et al.

Source: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica [APMIS] 2010 Sep 01; Vol. 118 (9), pp. 692-702.

Publication Type: Journal Article

Journal Info: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 8803400 Publication Model: Print Cited Medium: Internet ISSN: 1600-0463 (Electronic) Linking ISSN: 09034641 NLM ISO Abbreviation: APMIS Subsets: MEDLINE

Response of Schistosoma mansoni isolates having different drug sensitivity to praziquantel over several life cycle passages with and without therapeutic pressure.

Authors: Sabra AN Botros SS

Source: The Journal of parasitology [J Parasitol] 2008 Apr; Vol. 94 (2), pp. 537-41.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society of Parasitologists [etc.] Country of Publication: United States NLM ID: 7803124 Publication Model: Print Cited Medium: Print ISSN: 0022-3395 (Print) Linking ISSN: 00223395 NLM ISO Abbreviation: J Parasitol Subsets: MEDLINE

Schistosoma haematobium (Egyptian strain): rate of development and effect of praziquantel treatment.

Authors: Botros SS Hammam OA El-Lakkany NM et al.

Source: The Journal of parasitology [J Parasitol] 2008 Apr; Vol. 94 (2), pp. 386-94.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society of Parasitologists [etc.] Country of Publication: United States NLM ID: 7803124 Publication Model: Print Cited Medium: Print ISSN: 0022-3395 (Print) Linking ISSN: 00223395 NLM ISO Abbreviation: J Parasitol Subsets: MEDLINE

Assessment of combined therapy of recombinant glutathione S-transferase 26 and praziquantel on immunoparasitological responses

Authors: Botros SS Sabra AN Kamel MM et al.

Source: Arzneimittel-Forschung [Arzneimittelforschung] 2000 Oct; Vol. 50 (10), pp. 929-35.

Publication Type: Journal Article

Journal Info: Publisher: Editio Cantor Country of Publication: Germany NLM ID: 0372660 Publication Model: Print Cited Medium: Print ISSN: 0004-4172 (Print) Linking ISSN: 00044172 NLM ISO Abbreviation: Arzneimittelforschung

Screening of a PDE-focused library identifies imidazoles with in vitro and in vivo antischistosomal activity.

Authors: Botros SS William S Sabra AA et al.

Source: International journal for parasitology. Drugs and drug resistance [Int J Parasitol Drugs Drug Resist] 2019 Apr; Vol. 9, pp. 35-43. Date of Electronic Publication: 2019 Jan 14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101576715 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-3207 (Electronic) Linking ISSN: 22113207 NLM ISO Abbreviation: Int J Parasitol Drugs Drug Resist Subsets: MEDLINE

Antifibrotic effects of gallic acid on hepatic stellate cells: In vitro and in vivo mechanistic study.

Authors: El-Lakkany NM El-Maadawy WH Seif El-Din SH et al.

Source: Journal of traditional and complementary medicine [J Tradit Complement Med] 2018 Apr 27; Vol. 9 (1), pp. 45-53. Date of Electronic Publication: 2018 Apr 27 (Print Publication: 2019).

Publication Type: Journal Article

Journal Info: Publisher: Elsevier B.V. on behalf of the Center for Food and Biomolecules, National Taiwan University Country of Publication: Netherlands NLM ID: 101605474 Publication Model: eCollection Cited Medium: Print ISSN: 2225-4110 (Print) Linking ISSN: 22254110 NLM ISO Abbreviation: J Tradit Complement Med Subsets: PubMed not MEDLINE

Resveratrol mitigates hepatic injury in rats by regulating oxidative stress, nuclear factor-kappa B, and apoptosis.

Authors: Seif El-Din SH El-Lakkany NM Salem MB et al.

Source: Journal of advanced pharmaceutical technology & research [J Adv Pharm Technol Res] 2016 Jul-Sep; Vol. 7 (3), pp. 99-104.

Publication Type: Journal Article

Journal Info: Publisher: Medknow on behalf of Society of Pharmaceutical Education & Research Country of Publication: India NLM ID: 101537797 Publication Model: Print Cited Medium: Print ISSN: 2231-4040 (Print) Linking ISSN: 09762094 NLM ISO Abbreviation: J Adv Pharm Technol Res Subsets: PubMed not MEDLINE

Possible carcinogenic potential of dimethyl dimethoxy biphenyl dicarboxylate in experimental animals.

Authors: Botros SS El-Lakkany NM Hammam OA et al.

Source: Journal of advanced pharmaceutical technology & research [J Adv Pharm Technol Res] 2016 Apr-Jun; Vol. 7 (2), pp. 54-8.

Publication Type: Journal Article

Journal Info: Publisher: Medknow on behalf of Society of Pharmaceutical Education & Research Country of Publication: India NLM ID: 101537797 Publication Model: Print Cited Medium: Print ISSN: 2231-4040 (Print) Linking ISSN: 09762094 NLM ISO Abbreviation: J Adv Pharm Technol Res Subsets: PubMed not MEDLINE