Search Results - "Botstein, D."

A genomic-led strategy to anticipate drug safety effects.

Authors: Ferolito, Brian R. Horimoto, Andrea R. V. R. Gravel-Pucillo, Kai et al.

Source: PLoS Genetics. 7/16/2026, Vol. 22 Issue 7, p1-22. 22p.

An emergent biofilm program from inactivation of Candida albicans master regulators Efg1 and Ndt80.

Authors: Do, Eunsoo Zarnowski, Robert Andes, David R. et al.

Source: PLoS Pathogens. 7/20/2026, Vol. 22 Issue 7, p1-19. 19p.

Deciphering cell type-specific causal genetic effects on brain imaging-derived phenotypes and disorders with single-cell Mendelian randomization.

Authors: Yang, Anyi Zhao, Xingzhong Zhao, Xing-Ming et al.

Source: PLoS Computational Biology. 6/17/2026, Vol. 22 Issue 6, p1-32. 32p.

Animal Models and New Approach Methodologies in Retinal Disease Research: A Comprehensive Review.

Authors: Zynkowska, Aleksandra Kuźmiuk, Dominika Kiełbus, Maria et al.

Source: Applied Sciences (2076-3417); Jun2026, Vol. 16 Issue 11, p5576, 38p

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Position-dependent codon occurrence is associated with patterns of translational efficiency and ribosomal occupancy in the human transcriptome.

Authors: Subramanian, Kaavya Waugh, Nathan Shanks, Cole et al.

Source: PLoS Computational Biology. 7/20/2026, Vol. 22 Issue 7, p1-31. 31p.

Towards a unified model of aneuploid karyotype dynamics.

Authors: Hénault, Mathieu Wood, Lisa M. Heasley, Lydia R.

Source: PLoS Genetics. 6/18/2026, Vol. 22 Issue 6, p1-29. 29p.

Peripheral leukocyte transcriptomic changes in preweaned Holstein heifer calves with varying stages of Bovine Respiratory Disease.

Authors: Makratzakis, Lindsey C. Velasco, Joel A. Stegelmeier, Neils C. et al.

Source: PLoS ONE. 5/14/2026, Vol. 21 Issue 5, p1-21. 21p.

The differentiation of myeloid progenitors is effected by cascading waves of coordinated gene expression that remodel cellular physiology in a characteristic sequence.

Authors: Repele, Andrea Handzlik, Joanna Samarawickrama, Nimasha et al.

Source: PLoS Computational Biology. 5/12/2026, Vol. 22 Issue 5, p1-32. 32p.

ECOD: Classification of domains in AFDB Swiss-Prot structure predictions.

Authors: Schaeffer, R. Dustin Zhang, Jing Cong, Qian et al.

Source: PLoS Computational Biology. 3/30/2026, Vol. 22 Issue 3, p1-16. 16p.

Multilabel prediction of virus target proteins via multimodal graph representation learning.

Authors: Ma, Kuang Liu, Kaiyu Xin, Yuhui et al.

Source: PLoS Computational Biology. 5/26/2026, Vol. 22 Issue 5, p1-22. 22p.

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Transcriptomic insights into fruiting body malformations in Lentinula edodes.

Authors: Lin, Tong Du, Juan Li, Shipeng et al.

Source: Applied Microbiology & Biotechnology; 3/17/2026, Vol. 110 Issue 1, p1-12, 12p

An integrative multi-omics approach points to membrane composition as a key factor in E. coli persistence.

Authors: Cañas-Duarte, Silvia J. Sun, Lei Pérez-López, María Isabel et al.

Source: PLoS ONE. 6/29/2026, Vol. 21 Issue 6, p1-22. 22p.

Evaluating beta-tubulin variants as predictors of benzimidazole resistance across Caenorhabditis nematodes.

Authors: Shaver, Amanda O. McKeown, Ryan Reyes Otero, Joyce M. et al.

Source: PLoS Pathogens. 6/5/2026, Vol. 22 Issue 6, p1-35. 35p.

Genome-wide screening reveals the genetic basis of mammalian embryonic eye development.

Authors: Chee, Justine M. Lanoue, Louise Clary, Dave et al.

Source: BMC Biology. 2/3/2023, p1-15. 15p.

Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer's disease.

Authors: Valdes, Phoebe Caldwell, Andrew B. Liu, Qing et al.

Source: Alzheimer's Research & Therapy. 1/3/2025, Vol. 17 Issue 1, p1-20. 20p.

Putting BASIL in a BLT: A Bayesian filtering method for estimating the fitness effects of nascent adaptive mutations.

Authors: Kuo, Huan-Yu Kryazhimskiy, Sergey

Source: PLoS Computational Biology. 2/27/2026, Vol. 22 Issue 2, p1-27. 27p.

Unlocking the Zn-enriching potential of industrial yeast strains—an experimental journey from metal analysis to proteomics.

Authors: Grimmer, Gina Muenzner, Julia Schmacht, Maximillian et al.

Source: Applied Microbiology & Biotechnology; 1/10/2026, Vol. 110 Issue 1, p1-23, 23p

Ten rules for a structural bioinformatic analysis.

Authors: Wankowicz, Stephanie A.^1,2 (AUTHOR) stephanie@wankowiczlab.com

Source: PLoS Computational Biology. 10/31/2025, Vol. 21 Issue 10, p1-15. 15p.