Search Results - "Boxer MB"

12-Lipoxygenase Inhibition Improves Glycemia and Obesity-associated Inflammation in Male Human Gene Replacement Mice.

Authors: Kaylan KB Nargis T Figatner K et al.

Source: Endocrinology [Endocrinology] 2025 Apr 22; Vol. 166 (6).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE

SAR Studies around the SULT1A1-Activated Alkylator YC-1 as Cytotoxic Agents against Biliary Tract Cancer Cells.

Authors: Kong K Zhao W Shrimp JH et al.

Source: Journal of medicinal chemistry [J Med Chem] 2025 Sep 25; Vol. 68 (18), pp. 18885-18907. Date of Electronic Publication: 2025 Sep 16.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

12-Lipoxygenase inhibition improves glucose homeostasis and obesity-associated inflammation in human gene replacement mice.

Authors: Kaylan KB Nargis T Figatner K et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Jan 13. Date of Electronic Publication: 2025 Jan 13.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice.

Authors: Nargis T Muralidharan C Enriquez JR et al.

Source: JCI insight [JCI Insight] 2024 Dec 20; Vol. 9 (24). Date of Electronic Publication: 2024 Dec 20.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice.

Authors: Nargis T Muralidharan C Enriquez JR et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 29. Date of Electronic Publication: 2024 Oct 29.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

The HIV protease inhibitor, ritonavir, corrects diverse brain phenotypes across development in mouse model of DYT-TOR1A dystonia.

Authors: Caffall ZF Wilkes BJ Hernández-Martinez R et al.

Source: Science translational medicine [Sci Transl Med] 2021 Aug 18; Vol. 13 (607).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

A high dose KRP203 induces cytoplasmic vacuoles associated with altered phosphoinositide segregation and endosome expansion.

Authors: Kofuji S Wolfe K Sumita K et al.

Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Jul 23; Vol. 718, pp. 149981. Date of Electronic Publication: 2024 Apr 27.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells.

Authors: Ikeda Y Davis MI Sumita K et al.

Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Oct 30; Vol. 679, pp. 116-121. Date of Electronic Publication: 2023 Aug 26.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Novel Strategy to Combat the Procoagulant Phenotype in Heparin-Induced Thrombocytopenia Using 12-LOX Inhibition.

Authors: Renna SA Zhao X Kunapuli SP et al.

Source: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2023 Oct; Vol. 43 (10), pp. 1808-1817. Date of Electronic Publication: 2023 Jun 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE

SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers.

Authors: Shi L Shen W Davis MI et al.

Source: Nature cancer [Nat Cancer] 2023 Mar; Vol. 4 (3), pp. 365-381. Date of Electronic Publication: 2023 Mar 13.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE

Discovery of novel inhibitors of human galactokinase by virtual screening.

Authors: Hu X Zhang YQ Lee OW et al.

Source: Journal of computer-aided molecular design [J Comput Aided Mol Des] 2019 Apr; Vol. 33 (4), pp. 405-417. Date of Electronic Publication: 2019 Feb 26.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 8710425 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4951 (Electronic) Linking ISSN: 0920654X NLM ISO Abbreviation: J Comput Aided Mol Des Subsets: MEDLINE

Corrigendum: A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect.

Authors: Lopez-Serra P Marcilla M Villanueva A et al.

Source: Nature communications [Nat Commun] 2016 Nov 02; Vol. 7, pp. 13467. Date of Electronic Publication: 2016 Nov 02.

Publication Type: Journal Article; Published Erratum

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: PubMed not MEDLINE

Erratum: Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.

Authors: Kenny HA Lal-Nag M White EA et al.

Source: Nature communications [Nat Commun] 2016 Feb 03; Vol. 7, pp. 10649. Date of Electronic Publication: 2016 Feb 03.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: PubMed not MEDLINE

Discovery and Optimization of 2H-1λ²-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer.

Authors: Rohde JM Karavadhi S Pragani R et al.

Source: Journal of medicinal chemistry [J Med Chem] 2021 Apr 22; Vol. 64 (8), pp. 4913-4946. Date of Electronic Publication: 2021 Apr 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo.

Authors: Najm FJ Madhavan M Zaremba A et al.

Source: Nature [Nature] 2015 Jun 11; Vol. 522 (7555), pp. 216-20. Date of Electronic Publication: 2015 Apr 20.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.

Authors: Kenny HA Lal-Nag M White EA et al.

Source: Nature communications [Nat Commun] 2015 Feb 05; Vol. 6, pp. 6220. Date of Electronic Publication: 2015 Feb 05.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect.

Authors: Lopez-Serra P Marcilla M Villanueva A et al.

Source: Nature communications [Nat Commun] 2014 Apr 03; Vol. 5, pp. 3608. Date of Electronic Publication: 2014 Apr 03.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Elucidation of the structural basis of interaction of the BCR-ABL kinase inhibitor, nilotinib (Tasigna) with the human ABC drug transporter P-glycoprotein.

Authors: Shukla S Chufan EE Singh S et al.

Source: Leukemia [Leukemia] 2014 Apr; Vol. 28 (4), pp. 961-4. Date of Electronic Publication: 2014 Jan 14.

Publication Type: Letter; Research Support, N.I.H., Intramural

Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

A new family of covalent inhibitors block nucleotide binding to the active site of pyruvate kinase.

Authors: Morgan HP Walsh MJ Blackburn EA et al.

Source: The Biochemical journal [Biochem J] 2012 Nov 15; Vol. 448 (1), pp. 67-72.

Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.

Authors: Anastasiou D Yu Y Israelsen WJ et al.

Source: Nature chemical biology [Nat Chem Biol] 2012 Oct; Vol. 8 (10), pp. 839-47.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE