Search Results - "Brun, Reto"

In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains.

Authors: Abiodun, Oyindamola O. Brun, Reto Wittlin, Sergio

Source: Malaria Journal. 2013, Vol. 12 Issue 1, p1-4. 4p. 2 Charts.

Isomerization of 4-amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones.

Authors: Seebacher, Werner Saf, Robert Brun, Reto et al.

Source: Canadian Journal of Chemistry. Aug2006, Vol. 84 Issue 8, p1074-1078. 5p. 2 Diagrams, 1 Chart.

PLS-Prediction and Confirmation of Hydrojuglone Glucoside as the Antitrypanosomal Constituent of Juglans Spp.

Authors: Ellendorff, Therese Brun, Reto Kaiser, Marcel et al.

Source: Molecules. Jun2015, Vol. 20 Issue 6, p10082-10094. 13p. 1 Diagram, 3 Charts, 1 Graph.

Discovery of dual function acridones as a new antimalarial chemotype.

Authors: Kelly, Jane X. Smilkstein, Martin J. Brun, Reto et al.

Source: Nature. 5/14/2009, Vol. 459 Issue 7244, p270-273. 4p. 1 Black and White Photograph, 1 Diagram, 3 Charts, 1 Graph.

Subjects: Acridine, Antimalarials, Drug resistance, Drug development, Malaria treatment, Hemoglobins, Biodegradation, Quinoline, Drug interactions

Identification of an antimalarial synthetic trioxolane drug development candidate.

Authors: Vennerstrom, Jonathan L. Arbe-Barnes, Sarah Brun, Reto et al.

Source: Nature. 8/19/2004, Vol. 430 Issue 7002, p900-904. 5p.

Subjects: Antimalarials, Antiparasitic agents, Drug therapy, Pharmacokinetics, Pharmacology, Stomach, Reticulum (Ruminants)

Anti-Protozoal Activities of Cembrane-Type Diterpenes from Vietnamese Soft Corals.

Authors: Nguyen Phuong Thao Bui Thi Thuy Luyen Brun, Reto et al.

Source: Molecules. Jul2015, Vol. 20 Issue 7, p12459-12468. 10p. 1 Diagram, 1 Chart, 2 Graphs.

Antiprotozoal Activity of (E)-Cinnamic N-Acylhydrazone Derivatives.

Authors: Carvalho, Samir Aquino Kaiser, Marcel Brun, Reto et al.

Source: Molecules. Dec2014, Vol. 19 Issue 12, p20374-20381. 8p. 1 Diagram, 1 Chart.

Antiprotozoal Activity of Achillea ptarmica (Asteraceae) and Its Main Alkamide Constituents.

Authors: Althaus, Julia B. Kaiser, Marcel Brun, Reto et al.

Source: Molecules. May2014, Vol. 19 Issue 5, p6428-6438. 11p. 1 Diagram, 3 Charts, 1 Graph.

Aquaporin 2 Mutations in Trypanosoma brucei gambiense Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol.

Authors: Graf, Fabrice E. Ludin, Philipp Wenzler, Tanja et al.

Source: PLoS Neglected Tropical Diseases. 10/10/2013, Vol. 7 Issue 10, p1-7. 7p.

Safety, Pharmacokinetic, and Efficacy Studies of Oral DB868 in a First Stage Vervet Monkey Model of Human African Trypanosomiasis.

Authors: Thuita, John K. Wolf, Kristina K. Murilla, Grace A. et al.

Source: PLoS Neglected Tropical Diseases. 6/6/2013, Vol. 7 Issue 6, p1-13. 13p. 1 Diagram, 4 Charts, 6 Graphs.

Naphthoquinone Derivatives Exert Their Antitrypanosomal Activity via a Multi-Target Mechanism.

Authors: Pieretti, Simone Haanstra, Jurgen R. Mazet, Muriel et al.

Source: PLoS Neglected Tropical Diseases. 1/17/2013, Vol. 7 Issue 1, p1-12. 12p. 1 Color Photograph, 1 Black and White Photograph, 1 Chart, 5 Graphs.

Isothermal Microcalorimetry, a New Tool to Monitor Drug Action against Trypanosoma brucei and Plasmodium falciparum.

Authors: Wenzler, Tanja Steinhuber, Andrea Wittlin, Sergio et al.

Source: PLoS Neglected Tropical Diseases. 6/5/2012, Vol. 6 Issue 6, p1-7. 7p. 1 Chart, 4 Graphs.

Genetic Reconstruction of Protozoan rRNA Decoding Sites Provides a Rationale for Paromomycin Activity against Leishmania and Trypanosoma.

Authors: Hobbie, Sven N. Kaiser, Marcel Schmidt, Sebastian et al.

Source: PLoS Neglected Tropical Diseases. 5/24/2011, Vol. 5 Issue 5, p1-6. 6p.

Chemotherapy of Second Stage Human African Trypanosomiasis: Comparison between the Parenteral Diamidine DB829 and Its Oral Prodrug DB868 in Vervet Monkeys.

Authors: Thuita, John K. Wolf, Kristina K. Murilla, Grace A. et al.

Source: PLoS Neglected Tropical Diseases. 2/5/2015, Vol. 9 Issue 2, p1-22. 22p.

Agrochemicals against Malaria, Sleeping Sickness, Leishmaniasis and Chagas Disease.

Authors: Witschel, Matthias Rottmann, Matthias Kaiser, Marcel et al.

Source: PLoS Neglected Tropical Diseases. 10/25/2012, Vol. 6 Issue 10, p1-10. 10p. 4 Charts.

Pharmacology of DB844, an Orally Active aza Analogue of Pafuramidine, in a Monkey Model of Second Stage Human African Trypanosomiasis.

Authors: Thuita, John K. Wang, Michael Z. Kagira, John M. et al.

Source: PLoS Neglected Tropical Diseases. 7/24/2012, Vol. 6 Issue 7, p1-13. 13p. 1 Diagram, 4 Charts, 5 Graphs.

Fexinidazole – A New Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness.

Authors: Torreele, Els Bourdin Trunz, Bernadette Tweats, David et al.

Source: PLoS Neglected Tropical Diseases. 12/21/2010, Vol. 4 Issue 12, p1-15. 15p.

Adenosine Kinase of T. b. rhodesiense Identified as the Putative Target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine Using Chemical Proteomics.

Authors: Kuettel, Sabine Mosimann, Marc Mäser, Pascal et al.

Source: PLoS Neglected Tropical Diseases. 8/25/2009, Vol. 3 Issue 8, p1-9. 9p.

Spiroindolones, a Potent Compound Class for the Treatment of Malaria.

Authors: Rottmann, Matthias McNamara, Case Yeung, Bryan K. S. et al.

Source: Science (pre-March 2025). 9/3/2010, Vol. 329 Issue 5996, p1175-1180. 6p.

Anti-Trypanosomatid Elemanolide Sesquiterpene Lactones from Vernonia lasiopus O. Hoffm.

Authors: Kimani, Njogu M. Matasyoh, Josphat C. Kaiser, Marcel et al.

Source: Molecules. Apr2017, Vol. 22 Issue 4, p597. 9p. 1 Diagram, 3 Charts.