Search Results - "Burban, Audrey"

Predictive Value of Cellular Accumulation of Hydrophobic Bile Acids As a Marker of Cholestatic Drug Potential.

Authors: Burban, Audrey Sharanek, Ahmad Humbert, Lydie et al.

Source: Toxicological Sciences. Apr2019, Vol. 168 Issue 2, p474-485. 12p. 4 Charts, 4 Graphs.

Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs.

Authors: Sharanek, Ahmad Burban, Audrey Burbank, Matthew et al.

Source: Scientific Reports. 4/22/2016, p1-9. 9p.

Cellular accumulation and toxic effects of bile acids in cyclosporine A-treated HepaRG hepatocytes.

Authors: Sharanek, Ahmad Burban, Audrey Humbert, Lydie et al.

Source: Toxicological Sciences. Oct2015, Vol. 147 Issue 2, p573-587. 15p. 1 Diagram, 7 Graphs.

Pro-inflammatory cytokines enhance dilatation of bile canaliculi caused by cholestatic antibiotics.

Authors: Sharanek, Ahmad Burban, Audrey Ciriaci, Nadia et al.

Source: Toxicology in Vitro. Aug2019, Vol. 58, p51-59. 9p.

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Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes.

Authors: Burban, Audrey Sharanek, Ahmad Guguen-Guillouzo, Christiane et al.

Source: Free Radical Biology & Medicine. Feb2018, Vol. 115, p166-178. 13p.

In-Depth Proteome Analysis Highlights HepaRG Cells as a Versatile Cell System Surrogate for Primary Human Hepatocytes.

Authors: Tascher, Georg Burban, Audrey Camus, Sandrine et al.

Source: Cells (2073-4409). Feb2019, Vol. 8 Issue 2, p192. 1p.

Mechanistic Insights in Cytotoxic and Cholestatic Potential of the Endothelial Receptor Antagonists Using HepaRG Cells.

Authors: Burbank, Matthew Gibson Sharanek, Ahmad Burban, Audrey et al.

Source: Toxicological Sciences. Jun2017, Vol. 157 Issue 2, p451-464. 14p. 1 Diagram, 3 Charts, 4 Graphs.

Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes.

Authors: Bachour-El Azzi, Pamela Sharanek, Ahmad Burban, Audrey et al.

Source: Toxicological Sciences. May2015, Vol. 145 Issue 1, p157-168. 12p. 3 Color Photographs, 1 Black and White Photograph, 1 Diagram, 1 Chart, 2 Graphs.

Cholestatic drugs induce preferential accumulation of toxic bile acids in human HepaRG cells.

Authors: Sharanek, Ahmad Burban, Audrey Humbert, Lydie et al.

Source: Toxicology Letters. Oct2017 Supplement 1, Vol. 280, pS225-S225. 1p.

Antibiotic-induced cytotoxicity and cholestasis are related to an endoplasmic reticulum stress and amplified by inflammatory cytokines in human hepatocytes.

Authors: Burban, Audrey Sharanek, Ahmad Guguen-Guillouzo, Christiane et al.

Source: Toxicology Letters. Oct2017 Supplement 1, Vol. 280, pS225-S225. 1p.

Differential sensitivity of metabolically competent and non-competent HepaRG cells to apoptosis induced by diclofenac combined or not with TNF-α.

Authors: Al-Attrache, Houssein Sharanek, Ahmad Burban, Audrey et al.

Source: Toxicology Letters. Sep2016, Vol. 258, p71-86. 16p.

Preliminary pharmacokinetic investigation of two discoidin domain receptor 2 inhibitors in murine plasma and brain using liquid chromatography-tandem mass spectrometry analysis.

Authors: Gueroue P Burban A Sharanek A et al.

Source: Scientific reports [Sci Rep] 2026 Jun 24. Date of Electronic Publication: 2026 Jun 24.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Exploiting metabolic vulnerability in glioblastoma using a brain-penetrant drug with a safe profile.

Authors: Burban A Tessier C Larroquette M et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2025 Mar; Vol. 17 (3), pp. 469-503. Date of Electronic Publication: 2025 Feb 03.

Publication Type: Journal Article

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

Development and Validation of a LC-MS/MS Method for Ripretinib and Its Metabolite: Example of a Journey From Laboratory Bench to Routine Application With a Greenness Assessment.

Authors: Rakotovao C Sharanek A Burban A et al.

Source: Biomedical chromatography : BMC [Biomed Chromatogr] 2025 Sep; Vol. 39 (9), pp. e70190.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS.

Authors: Rasool D Burban A Sharanek A et al.

Source: EMBO reports [EMBO Rep] 2024 Mar; Vol. 25 (3), pp. 1256-1281. Date of Electronic Publication: 2024 Mar 01.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

Protocol for real-time measurement of mitochondrial bioenergetics in 3D-cultured brain tumor stem cells using the Resipher system.

Authors: Tessier C Toujas M Pagano Zottola AC et al.

Source: STAR protocols [STAR Protoc] 2025 Mar 21; Vol. 6 (1), pp. 103651. Date of Electronic Publication: 2025 Feb 24.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE

Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis.

Authors: Guyon J Fernandez-Moncada I Larrieu CM et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2022 Dec 07; Vol. 14 (12), pp. e15343. Date of Electronic Publication: 2022 Oct 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

Targeting glioblastoma with a brain-penetrant drug that impairs brain tumor stem cells via NLE1-Notch1 complex.

Authors: Burban A Sharanek A Hernandez-Corchado A et al.

Source: Stem cell reports [Stem Cell Reports] 2024 Nov 12; Vol. 19 (11), pp. 1534-1547. Date of Electronic Publication: 2024 Oct 17.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation.

Authors: Sharanek A Burban A Laaper M et al.

Source: Nature communications [Nat Commun] 2020 Aug 17; Vol. 11 (1), pp. 4116. Date of Electronic Publication: 2020 Aug 17.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE