Search Results - "Burge, Christopher"

A research roadmap for SCN8A-related disorders: addressing knowledge gaps and aligning research priorities across stakeholders.

Authors: Berg, Anne T. Burge, Christopher Conecker, Gabi et al.

Source: Orphanet Journal of Rare Diseases. 8/19/2025, Vol. 20 Issue 1, p1-17. 17p.

An interpretable model of pre-mRNA splicing for animal and plant genes.

Authors: McCue, Kayla Burge, Christopher B.

Source: Science Advances. 5/10/2024, Vol. 10 Issue 19, p1-19. 19p.

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Promoter directionality is controlled by U1 snRNP and polyadenylation signals.

Authors: Almada, Albert E. Wu, Xuebing Kriz, Andrea J. et al.

Source: Nature. 7/18/2013, Vol. 499 Issue 7458, p360-363. 4p. 4 Graphs.

Subjects: Genetic transcription, Mammal genomes, Genes, RNA polymerases, Embryonic stem cells, Antisense RNA

MBNL proteins repress ES-cell-specific alternative splicing and reprogramming.

Authors: Han, Hong Irimia, Manuel Ross, P. Joel et al.

Source: Nature. 6/13/2013, Vol. 498 Issue 7453, p241-245. 5p. 2 Diagrams, 2 Graphs.

Subjects: Genetic regulation, Chromatin, Embryonic stem cells, Neural circuitry, Carrier proteins, Cell differentiation

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Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues.

Authors: Merkin, Jason Russell, Caitlin Ping Chen et al.

Source: Science (pre-March 2025). 12/21/2012, Vol. 338 Issue 6114, p1593-1599. 7p.

Subjects: Messenger RNA, Alternative RNA splicing, Mammal evolution, Antisense DNA, Nucleotide sequence, Exons (Genetics), Tissue analysis, Gene expression in mammals, Phosphorylation, Kinase regulation

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Alternative isoform regulation in human tissue transcriptomes.

Authors: Wang, Eric T. Sandberg, Rickard Luo, Shujun et al.

Source: Nature. 11/27/2008, Vol. 456 Issue 7221, p470-476. 7p. 1 Diagram, 1 Chart, 3 Graphs.

Subjects: Messenger RNA, Genetic polymorphisms, Cell lines, Tissue extracts, Nucleotide sequence, Gene mapping, RNA splicing, Scission (Chemistry)

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites.

Authors: Sandberg, Rickard Neilson, Joel R. Sarma, Arup et al.

Source: Science (pre-March 2025). 6/20/2008, Vol. 320 Issue 5883, p1643-1647. 5p. 3 Graphs.

Subjects: Messenger RNA, Cell proliferation, Cell growth, Cell cycle, Molecular cell proliferation, Gene expression, Tissues, Lymphocytes, Growth factors

The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution.

Authors: Farh, Kyle Kai-How Crimson, Andrew Jan, Calvin et al.

Source: Science (pre-March 2025). 12/16/2005, Vol. 310 Issue 5755, p1817-1821. 5p. 4 Graphs.

Subjects: Messenger RNA, Biological evolution, Nucleotides, Genes, Tissues, Surgery

Predictive Identification of Exonic Splicing Enhancers in Human Genes.

Authors: Fairbrother, William G. Ru-Fang Yeh Sharp, Phillip A. et al.

Source: Science (pre-March 2025). 8/9/2002, Vol. 297 Issue 5583, p1007-1013. 7p. 3 Diagrams, 1 Chart, 4 Graphs.

Subjects: Exons (Genetics), Genetic mutation

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