Search Results - "Burger PB"

FEP Augmentation as a Means to Solve Data Paucity Problems for Machine Learning in Chemical Biology.

Authors: Burger PB Hu X Balabin I et al.

Source: Journal of chemical information and modeling [J Chem Inf Model] 2024 May 13; Vol. 64 (9), pp. 3812-3825. Date of Electronic Publication: 2024 Apr 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

Error Tolerance of Machine Learning Algorithms across Contemporary Biological Targets.

Authors: Kaiser TM Burger PB

Source: Molecules (Basel, Switzerland) [Molecules] 2019 Jun 04; Vol. 24 (11). Date of Electronic Publication: 2019 Jun 04.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation.

Authors: Benton TZ Mills CM Turner JM et al.

Source: RSC advances [RSC Adv] 2021 Oct 11; Vol. 11 (53), pp. 33260-33270. Date of Electronic Publication: 2021 Oct 11 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE

Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors.

Authors: Strong KL Epplin MP Ogden KK et al.

Source: ACS chemical neuroscience [ACS Chem Neurosci] 2021 Jan 06; Vol. 12 (1), pp. 79-98. Date of Electronic Publication: 2020 Dec 16.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

Negative allosteric modulation of GluN1/GluN3 NMDA receptors.

Authors: Zhu Z Yi F Epplin MP et al.

Source: Neuropharmacology [Neuropharmacology] 2020 Oct 01; Vol. 176, pp. 108117. Date of Electronic Publication: 2020 May 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail.

Authors: Burger PB Williams M Sprenger J et al.

Source: Malaria journal [Malar J] 2015 Feb 05; Vol. 14, pp. 54. Date of Electronic Publication: 2015 Feb 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

Discovery-2: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria.

Authors: Mpangase PT Szolkiewicz MJ le Grange M et al.

Source: Malaria journal [Malar J] 2013 Mar 28; Vol. 12, pp. 116. Date of Electronic Publication: 2013 Mar 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101139802 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2875 (Electronic) Linking ISSN: 14752875 NLM ISO Abbreviation: Malar J Subsets: MEDLINE

Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum.

Authors: Reeksting SB Müller IB Burger PB et al.

Source: The Biochemical journal [Biochem J] 2013 Jan 01; Vol. 449 (1), pp. 175-87.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

Accelerated Discovery of Potent Fusion Inhibitors for Respiratory Syncytial Virus.

Authors: Pribut N Kaiser TM Wilson RJ et al.

Source: ACS infectious diseases [ACS Infect Dis] 2020 May 08; Vol. 6 (5), pp. 922-929. Date of Electronic Publication: 2020 Apr 20.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

NMDA receptor channel gating control by the pre-M1 helix.

Authors: McDaniel MJ Ogden KK Kell SA et al.

Source: The Journal of general physiology [J Gen Physiol] 2020 Apr 06; Vol. 152 (4).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985110R Publication Model: Print Cited Medium: Internet ISSN: 1540-7748 (Electronic) Linking ISSN: 00221295 NLM ISO Abbreviation: J Gen Physiol Subsets: MEDLINE

One Among Millions: The Chemical Space of Nucleic Acid-Like Molecules.

Authors: Cleaves HJ 2nd Butch C Burger PB et al.

Source: Journal of chemical information and modeling [J Chem Inf Model] 2019 Oct 28; Vol. 59 (10), pp. 4266-4277. Date of Electronic Publication: 2019 Sep 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

A Machine Learning Approach for Predicting HIV Reverse Transcriptase Mutation Susceptibility of Biologically Active Compounds.

Authors: Kaiser TM Burger PB Butch CJ et al.

Source: Journal of chemical information and modeling [J Chem Inf Model] 2018 Aug 27; Vol. 58 (8), pp. 1544-1552. Date of Electronic Publication: 2018 Jul 17.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

The Bioactive Protein-Ligand Conformation of GluN2C-Selective Positive Allosteric Modulators Bound to the NMDA Receptor.

Authors: Kaiser TM Kell SA Kusumoto H et al.

Source: Molecular pharmacology [Mol Pharmacol] 2018 Feb; Vol. 93 (2), pp. 141-156. Date of Electronic Publication: 2017 Dec 14.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE

The Structure-Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-d-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-d-Aspartate Receptors.

Authors: Strong KL Epplin MP Bacsa J et al.

Source: Journal of medicinal chemistry [J Med Chem] 2017 Jul 13; Vol. 60 (13), pp. 5556-5585. Date of Electronic Publication: 2017 Jun 26.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Functional Evaluation of a De Novo GRIN2A Mutation Identified in a Patient with Profound Global Developmental Delay and Refractory Epilepsy.

Authors: Chen W Tankovic A Burger PB et al.

Source: Molecular pharmacology [Mol Pharmacol] 2017 Apr; Vol. 91 (4), pp. 317-330. Date of Electronic Publication: 2017 Jan 26.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.

Authors: Swanger SA Chen W Wells G et al.

Source: American journal of human genetics [Am J Hum Genet] 2016 Dec 01; Vol. 99 (6), pp. 1261-1280. Date of Electronic Publication: 2016 Nov 10.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator.

Authors: Khatri A Burger PB Swanger SA et al.

Source: Molecular pharmacology [Mol Pharmacol] 2014 Nov; Vol. 86 (5), pp. 548-60. Date of Electronic Publication: 2014 Sep 09.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE

Novel S-adenosyl-L-methionine decarboxylase inhibitors as potent antiproliferative agents against intraerythrocytic Plasmodium falciparum parasites.

Authors: le Roux D Burger PB Niemand J et al.

Source: International journal for parasitology. Drugs and drug resistance [Int J Parasitol Drugs Drug Resist] 2013 Dec 05; Vol. 4 (1), pp. 28-36. Date of Electronic Publication: 2013 Dec 05 (Print Publication: 2014).

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101576715 Publication Model: eCollection Cited Medium: Print ISSN: 2211-3207 (Print) Linking ISSN: 22113207 NLM ISO Abbreviation: Int J Parasitol Drugs Drug Resist Subsets: PubMed not MEDLINE

Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators.

Authors: Burger PB Yuan H Karakas E et al.

Source: Molecular pharmacology [Mol Pharmacol] 2012 Aug; Vol. 82 (2), pp. 344-59. Date of Electronic Publication: 2012 May 17.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE

Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators.

Authors: Acker TM Yuan H Hansen KB et al.

Source: Molecular pharmacology [Mol Pharmacol] 2011 Nov; Vol. 80 (5), pp. 782-95. Date of Electronic Publication: 2011 Aug 01.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE