Search Results - "Burger WAC"

Cryo-EM reveals an extrahelical allosteric binding site at the M5 mAChR.

Authors: Burger WAC Mobbs JI Rana B et al.

Source: Nature communications [Nat Commun] 2025 Jul 31; Vol. 16 (1), pp. 7046. Date of Electronic Publication: 2025 Jul 31.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Importance of receptor expression in the classification of novel ligands at the M2 muscarinic acetylcholine receptor.

Authors: Jiang Y Yeasmin M Gondin AB et al.

Source: British journal of pharmacology [Br J Pharmacol] 2024 Jul; Vol. 181 (14), pp. 2338-2350. Date of Electronic Publication: 2023 Jan 20.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Xanomeline displays concomitant orthosteric and allosteric binding modes at the M4 mAChR.

Authors: Burger WAC Pham V Vuckovic Z et al.

Source: Nature communications [Nat Commun] 2023 Sep 06; Vol. 14 (1), pp. 5440. Date of Electronic Publication: 2023 Sep 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Recessive CHRM5 variant as a potential cause of neurogenic bladder.

Authors: Schneider S Schierbaum L Burger WAC et al.

Source: American journal of medical genetics. Part A [Am J Med Genet A] 2023 Aug; Vol. 191 (8), pp. 2083-2091. Date of Electronic Publication: 2023 May 22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101235741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4833 (Electronic) Linking ISSN: 15524825 NLM ISO Abbreviation: Am J Med Genet A Subsets: MEDLINE

Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics.

Authors: Vuckovic Z Wang J Pham V et al.

Source: ELife [Elife] 2023 May 30; Vol. 12. Date of Electronic Publication: 2023 May 30.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Cryo-EM reveals a new allosteric binding site at the M5 mAChR.

Authors: Burger WAC Mobbs JI Rana B et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Feb 08. Date of Electronic Publication: 2025 Feb 08.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Correction: Toward an understanding of the structural basis of allostery in muscarinic acetylcholine receptors.

Authors: Burger WAC Sexton PM Christopoulos A et al.

Source: The Journal of general physiology [J Gen Physiol] 2025 Jan 06; Vol. 157 (1). Date of Electronic Publication: 2024 Dec 19.

Publication Type: Published Erratum

Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985110R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-7748 (Electronic) Linking ISSN: 00221295 NLM ISO Abbreviation: J Gen Physiol Subsets: MEDLINE; PubMed not MEDLINE

Positive allosteric modulation of a GPCR ternary complex.

Authors: Burger WAC Draper-Joyce CJ Valant C et al.

Source: Science advances [Sci Adv] 2024 Sep 13; Vol. 10 (37), pp. eadp7040. Date of Electronic Publication: 2024 Sep 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors.

Authors: Mobbs JI Black KA Tran M et al.

Source: Blood [Blood] 2023 Oct 05; Vol. 142 (14), pp. 1233-1242.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

Structural basis of efficacy-driven ligand selectivity at GPCRs.

Authors: Powers AS Pham V Burger WAC et al.

Source: Nature chemical biology [Nat Chem Biol] 2023 Jul; Vol. 19 (7), pp. 805-814. Date of Electronic Publication: 2023 Feb 13.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

Author Correction: Structural basis of efficacy-driven ligand selectivity at GPCRs.

Authors: Powers AS Pham V Burger WAC et al.

Source: Nature chemical biology [Nat Chem Biol] 2023 Apr; Vol. 19 (4), pp. 529.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE; PubMed not MEDLINE

Identification of a Novel Allosteric Site at the M5 Muscarinic Acetylcholine Receptor.

Authors: Burger WAC Gentry PR Berizzi AE et al.

Source: ACS chemical neuroscience [ACS Chem Neurosci] 2021 Aug 18; Vol. 12 (16), pp. 3112-3123. Date of Electronic Publication: 2021 Aug 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

Crystal structure of the M5 muscarinic acetylcholine receptor.

Authors: Vuckovic Z Gentry PR Berizzi AE et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Dec 17; Vol. 116 (51), pp. 26001-26007. Date of Electronic Publication: 2019 Nov 26.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity.

Authors: Jörg M van der Westhuizen ET Khajehali E et al.

Source: ACS chemical neuroscience [ACS Chem Neurosci] 2019 Mar 20; Vol. 10 (3), pp. 1099-1114. Date of Electronic Publication: 2018 Dec 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

Toward an understanding of the structural basis of allostery in muscarinic acetylcholine receptors.

Authors: Burger WAC Sexton PM Christopoulos A et al.

Source: The Journal of general physiology [J Gen Physiol] 2018 Oct 01; Vol. 150 (10), pp. 1360-1372. Date of Electronic Publication: 2018 Sep 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985110R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-7748 (Electronic) Linking ISSN: 00221295 NLM ISO Abbreviation: J Gen Physiol Subsets: MEDLINE

Structure-Affinity Relationships and Structure-Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A3 Receptor Antagonists.

Authors: Xia L Burger WAC van Veldhoven JPD et al.

Source: Journal of medicinal chemistry [J Med Chem] 2017 Sep 14; Vol. 60 (17), pp. 7555-7568. Date of Electronic Publication: 2017 Aug 30.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE