Search Results - "Burghardt TP"

Neural-symbolic hybrid model for myosin complex in cardiac ventriculum decodes structural bases for inheritable heart disease from its genetic encoding.

Authors: Burghardt TP; Department of Biochemistry and Molecular Biology, 200 First St. SW, Mayo Clinic Rochester, Rochester, MN, 55905, USA. Electronic address: burghardt@mayo.edu.

Source: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2025 Mar; Vol. 765, pp. 110323. Date of Electronic Publication: 2025 Jan 30.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

Hypercontractile mutant of ventricular myosin essential light chain leads to disruption of sarcomeric structure and function and results in restrictive cardiomyopathy in mice.

Authors: Yuan CC Kazmierczak K Liang J et al.

Source: Cardiovascular research [Cardiovasc Res] 2017 Aug 01; Vol. 113 (10), pp. 1124-1136.

Publication Type: Journal Article

Journal Info: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

Natural variant frequencies across domains from different sarcomere proteins cross-correlate to identify inter-protein contacts associated with cardiac muscle function and disease.

Authors: Burghardt TP; Department of Biochemistry and Molecular Biology, Mayo Clinic Rochester, 200 First St. SW, Rochester, MN, 55905, USA. burghardt@mayo.edu.

Source: Molecular biomedicine [Mol Biomed] 2021 Nov 15; Vol. 2 (1), pp. 35. Date of Electronic Publication: 2021 Nov 15.

Publication Type: Journal Article

Journal Info: Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 9918283581406676 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-8651 (Electronic) Linking ISSN: 26628651 NLM ISO Abbreviation: Mol Biomed Subsets: PubMed not MEDLINE

Auxotonic to isometric contraction transitioning in a beating heart causes myosin step-size to down shift.

Authors: Burghardt TP Sun X Wang Y et al.

Source: PloS one [PLoS One] 2017 Apr 19; Vol. 12 (4), pp. e0174690. Date of Electronic Publication: 2017 Apr 19 (Print Publication: 2017).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

In vitro and in vivo single myosin step-sizes in striated muscle.

Authors: Burghardt TP Sun X Wang Y et al.

Source: Journal of muscle research and cell motility [J Muscle Res Cell Motil] 2015 Dec; Vol. 36 (6), pp. 463-77. Date of Electronic Publication: 2016 Jan 04.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Springer Netherlands Country of Publication: Netherlands NLM ID: 8006298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2657 (Electronic) Linking ISSN: 01424319 NLM ISO Abbreviation: J Muscle Res Cell Motil Subsets: MEDLINE

The frequency-dependent effect of electrical fields on the mobility of intracellular vesicles in astrocytes.

Authors: Wang Y Burghardt TP Worrell GA et al.

Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Jan 01; Vol. 534, pp. 429-435. Date of Electronic Publication: 2020 Dec 03.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Cell biology. Heart brakes.

Authors: Burghardt TP Ajtai K

Source: Science (New York, N.Y.) [Science] 2012 Sep 07; Vol. 337 (6099), pp. 1182-3.

Publication Type: Journal Article; Comment

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Single molecule fluorescence image patterns linked to dipole orientation and axial position: application to myosin cross-bridges in muscle fibers.

Authors: Burghardt TP; Department of Biochemistry and Molecular Biology, Mayo Clinic Rochester, Rochester, Minnesota, United States of America. burghardt@mayo.edu

Source: PloS one [PLoS One] 2011 Feb 08; Vol. 6 (2), pp. e16772. Date of Electronic Publication: 2011 Feb 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Myosin individualized: single nucleotide polymorphisms in energy transduction.

Authors: Burghardt TP Neff KL Wieben ED et al.

Source: BMC genomics [BMC Genomics] 2010 Mar 15; Vol. 11, pp. 172. Date of Electronic Publication: 2010 Mar 15.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164 (Electronic) Linking ISSN: 14712164 NLM ISO Abbreviation: BMC Genomics Subsets: MEDLINE

Demographic model for inheritable cardiac disease.

Authors: Burghardt TP; Department of Biochemistry and Molecular Biology and Physiology and Biomedical Engineering, 200 First St. SW, Mayo Clinic Rochester, Rochester, MN, 55905, USA. Electronic address: burghardt@mayo.edu.

Source: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2019 Sep 15; Vol. 672, pp. 108056. Date of Electronic Publication: 2019 Jul 26.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

PDLIM4, an actin binding protein, suppresses prostate cancer cell growth.

Authors: Vanaja DK Grossmann ME Cheville JC et al.

Source: Cancer investigation [Cancer Invest] 2009 Mar; Vol. 27 (3), pp. 264-72.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8307154 Publication Model: Print Cited Medium: Internet ISSN: 1532-4192 (Electronic) Linking ISSN: 07357907 NLM ISO Abbreviation: Cancer Invest Subsets: MEDLINE

Uncured PDMS inhibits myosin in vitro motility in a microfluidic flow cell.

Authors: Wang Y Burghardt TP

Source: Analytical biochemistry [Anal Biochem] 2018 Dec 15; Vol. 563, pp. 56-60. Date of Electronic Publication: 2018 Oct 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0370535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0309 (Electronic) Linking ISSN: 00032697 NLM ISO Abbreviation: Anal Biochem

Cardiac and skeletal actin substrates uniquely tune cardiac myosin strain-dependent mechanics.

Authors: Wang Y Ajtai K Burghardt TP

Source: Open biology [Open Biol] 2018 Nov 21; Vol. 8 (11). Date of Electronic Publication: 2018 Nov 21.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Royal Society Pub Country of Publication: England NLM ID: 101580419 Publication Model: Electronic Cited Medium: Internet ISSN: 2046-2441 (Electronic) Linking ISSN: 20462441 NLM ISO Abbreviation: Open Biol Subsets: MEDLINE

Neural/Bayes network predictor for inheritable cardiac disease pathogenicity and phenotype.

Authors: Burghardt TP Ajtai K

Source: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2018 Jun; Vol. 119, pp. 19-27. Date of Electronic Publication: 2018 Apr 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Academic Press Country of Publication: England NLM ID: 0262322 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8584 (Electronic) Linking ISSN: 00222828 NLM ISO Abbreviation: J Mol Cell Cardiol Subsets: MEDLINE

Single cardiac ventricular myosins are autonomous motors.

Authors: Wang Y Yuan CC Kazmierczak K et al.

Source: Open biology [Open Biol] 2018 Apr; Vol. 8 (4).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Royal Society Pub Country of Publication: England NLM ID: 101580419 Publication Model: Print Cited Medium: Internet ISSN: 2046-2441 (Electronic) Linking ISSN: 20462441 NLM ISO Abbreviation: Open Biol Subsets: MEDLINE

In vitro actin motility velocity varies linearly with the number of myosin impellers.

Authors: Wang Y Burghardt TP

Source: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2017 Mar 15; Vol. 618, pp. 1-8. Date of Electronic Publication: 2017 Jan 25.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

In vivo myosin step-size from zebrafish skeletal muscle.

Authors: Burghardt TP Ajtai K Sun X et al.

Source: Open biology [Open Biol] 2016 May; Vol. 6 (5). Date of Electronic Publication: 2016 May 25.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Royal Society Pub Country of Publication: England NLM ID: 101580419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2046-2441 (Electronic) Linking ISSN: 20462441 NLM ISO Abbreviation: Open Biol Subsets: MEDLINE

N-Terminus of Cardiac Myosin Essential Light Chain Modulates Myosin Step-Size.

Authors: Wang Y Ajtai K Kazmierczak K et al.

Source: Biochemistry [Biochemistry] 2016 Jan 12; Vol. 55 (1), pp. 186-98. Date of Electronic Publication: 2015 Dec 29.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

In vivo orientation of single myosin lever arms in zebrafish skeletal muscle.

Authors: Sun X Ekker SC Shelden EA et al.

Source: Biophysical journal [Biophys J] 2014 Sep 16; Vol. 107 (6), pp. 1403-14.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0370626 Publication Model: Print Cited Medium: Internet ISSN: 1542-0086 (Electronic) Linking ISSN: 00063495 NLM ISO Abbreviation: Biophys J Subsets: MEDLINE

Analytical comparison of natural and pharmaceutical ventricular myosin activators.

Authors: Wang Y Ajtai K Burghardt TP

Source: Biochemistry [Biochemistry] 2014 Aug 19; Vol. 53 (32), pp. 5298-306. Date of Electronic Publication: 2014 Aug 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE