Search Results - "Burghaus R"

Good Practices in Model-Informed Drug Discovery and Development: Practice, Application, and Documentation.

Authors: Marshall, SF Burghaus, R Cosson, V et al.

Source: CPT: Pharmacometrics & Systems Pharmacology. Mar2016, Vol. 5 Issue 3, p93-122. 30p.

Polycystic ovary syndrome and elevated body mass index independently increase type 2 diabetes risk with obesity-mediated risk dominating: a real-world data analysis of US patients.

Authors: Sharafutdinov K Hilpert J Burghaus R et al.

Source: Fertility and sterility [Fertil Steril] 2026 Mar; Vol. 125 (3), pp. 506-514. Date of Electronic Publication: 2025 Sep 12.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier for the American Society for Reproductive Medicine Country of Publication: United States NLM ID: 0372772 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-5653 (Electronic) Linking ISSN: 00150282 NLM ISO Abbreviation: Fertil Steril Subsets: MEDLINE

In-Depth Analysis of the Selection of PBPK Modeling Tools: Bibliometric and Social Network Analysis of the Open Systems Pharmacology Community.

Authors: Dallmann A Teutonico D Schaller S et al.

Source: Journal of clinical pharmacology [J Clin Pharmacol] 2024 Sep; Vol. 64 (9), pp. 1055-1067. Date of Electronic Publication: 2024 May 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

Harnessing Open-Source Solutions: Insights From the First Open Systems Pharmacology (OSP) Community Conference.

Authors: Dallmann A Feick D Balazki P et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2025 May; Vol. 14 (5), pp. 822-827. Date of Electronic Publication: 2025 Apr 03.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

Model-informed approach to support pediatric dosing for the pan-PI3K inhibitor copanlisib in children and adolescents with relapsed/refractory solid tumors.

Authors: Morcos PN Schlender J Burghaus R et al.

Source: Clinical and translational science [Clin Transl Sci] 2023 Jul; Vol. 16 (7), pp. 1197-1209. Date of Electronic Publication: 2023 Apr 18.

Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

Early prediction of decompensation (EPOD) score: Non-invasive determination of cirrhosis decompensation risk.

Authors: Schneider ARP Schneider CV Schneider KM et al.

Source: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2022 Mar; Vol. 42 (3), pp. 640-650. Date of Electronic Publication: 2022 Feb 03.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE

NT-proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure.

Authors: Schmitt W Rühs H Burghaus R et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Aug; Vol. 110 (2), pp. 498-507. Date of Electronic Publication: 2021 Mar 27.

Publication Type: Journal Article; Meta-Analysis

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small-Molecule Compounds in Children.

Authors: Ince I Dallmann A Frechen S et al.

Source: Journal of clinical pharmacology [J Clin Pharmacol] 2021 Jun; Vol. 61 Suppl 1, pp. S70-S82.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

Quantitative Systems Pharmacology Approaches for Immuno-Oncology: Adding Virtual Patients to the Development Paradigm.

Authors: Chelliah V Lazarou G Bhatnagar S et al.

Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Mar; Vol. 109 (3), pp. 605-618. Date of Electronic Publication: 2020 Aug 14.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE

Applied physiologically-based pharmacokinetic modeling to assess uridine diphosphate-glucuronosyltransferase-mediated drug-drug interactions for Vericiguat.

Authors: Frechen S Ince I Dallmann A et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Jan; Vol. 13 (1), pp. 79-92. Date of Electronic Publication: 2023 Oct 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

Predictive Pediatric Modeling and Simulation Using Ontogeny Information.

Authors: Ince I Solodenko J Frechen S et al.

Source: Journal of clinical pharmacology [J Clin Pharmacol] 2019 Sep; Vol. 59 Suppl 1, pp. S95-S103.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

Baseline clusters and the response to positive airway pressure treatment in obstructive sleep apnoea patients: longitudinal data from the European Sleep Apnea Database cohort.

Authors: Yassen A Coboeken K Bailly S et al.

Source: ERJ open research [ERJ Open Res] 2022 Oct 31; Vol. 8 (4). Date of Electronic Publication: 2022 Oct 31 (Print Publication: 2022).

Publication Type: Journal Article

Journal Info: Publisher: European Respiratory Society Country of Publication: England NLM ID: 101671641 Publication Model: eCollection Cited Medium: Print ISSN: 2312-0541 (Print) Linking ISSN: 23120541 NLM ISO Abbreviation: ERJ Open Res Subsets: PubMed not MEDLINE

Data-driven identification of heart failure disease states and progression pathways using electronic health records.

Authors: Nagamine T Gillette B Kahoun J et al.

Source: Scientific reports [Sci Rep] 2022 Oct 25; Vol. 12 (1), pp. 17871. Date of Electronic Publication: 2022 Oct 25.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

CKD subpopulations defined by risk-factors: A longitudinal analysis of electronic health records.

Authors: Ramaswamy R Wee SN George K et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2021 Nov; Vol. 10 (11), pp. 1343-1356. Date of Electronic Publication: 2021 Sep 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

Data-driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment.

Authors: Fendt R Hofmann U Schneider ARP et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2021 Jul; Vol. 10 (7), pp. 782-793. Date of Electronic Publication: 2021 Jun 26.

Publication Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions.

Authors: Frechen S Solodenko J Wendl T et al.

Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2021 Jun; Vol. 10 (6), pp. 633-644. Date of Electronic Publication: 2021 May 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE

Algorithmic surveillance of ICU patients with acute respiratory distress syndrome (ASIC): protocol for a multicentre stepped-wedge cluster randomised quality improvement strategy.

Authors: Marx G Bickenbach J Fritsch SJ et al.

Source: BMJ open [BMJ Open] 2021 Apr 08; Vol. 11 (4), pp. e045589. Date of Electronic Publication: 2021 Apr 08.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE

Multiscale classification of heart failure phenotypes by unsupervised clustering of unstructured electronic medical record data.

Authors: Nagamine T Gillette B Pakhomov A et al.

Source: Scientific reports [Sci Rep] 2020 Dec 07; Vol. 10 (1), pp. 21340. Date of Electronic Publication: 2020 Dec 07.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Contribution of rivaroxaban to the international normalized ratio when switching to warfarin for anticoagulation as determined by simulation studies.

Authors: Siegmund HU Burghaus R Kubitza D et al.

Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2015 Jun; Vol. 79 (6), pp. 959-66.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

Computational investigation of potential dosing schedules for a switch of medication from warfarin to rivaroxaban-an oral, direct Factor Xa inhibitor.

Authors: Burghaus R Coboeken K Gaub T et al.

Source: Frontiers in physiology [Front Physiol] 2014 Nov 07; Vol. 5, pp. 417. Date of Electronic Publication: 2014 Nov 07 (Print Publication: 2014).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101549006 Publication Model: eCollection Cited Medium: Print ISSN: 1664-042X (Print) Linking ISSN: 1664042X NLM ISO Abbreviation: Front Physiol Subsets: PubMed not MEDLINE