Search Results - "Burkhardt, Daniel B."

Active learning framework leveraging transcriptomics identifies modulators of disease phenotypes.

Authors: DeMeo, Benjamin Nesbitt, Charlotte Miller, Samuel A. et al.

Source: Science. 11/27/2025, Vol. 390 Issue 6776, p1-13. 13p.

Subjects: Transcriptomes, Drug discovery, Active learning, Machine learning, Therapeutics, Phenotypes, Drugs

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Quantifying the effect of experimental perturbations at single-cell resolution.

Authors: Burkhardt, Daniel B. Stanley III, Jay S. Tong, Alexander et al.

Source: Nature Biotechnology. May2021, Vol. 39 Issue 5, p619-629. 11p.

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AAnet Resolves a Continuum of Spatially Localized Cell States to Unveil Intratumoral Heterogeneity.

Authors: Venkat A Youlten SE San Juan BP et al.

Source: Cancer discovery [Cancer Discov] 2025 Oct 06; Vol. 15 (10), pp. 2139-2165.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

Modeling uniquely human gene regulatory function via targeted humanization of the mouse genome.

Authors: Dutrow EV Emera D Yim K et al.

Source: Nature communications [Nat Commun] 2022 Jan 13; Vol. 13 (1), pp. 304. Date of Electronic Publication: 2022 Jan 13.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

How to Build the Virtual Cell with Artificial Intelligence: Priorities and Opportunities.

Authors: Bunne C Roohani Y Rosen Y et al.

Source: ArXiv [ArXiv] 2024 Oct 14. Date of Electronic Publication: 2024 Oct 14.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101759493 Publication Model: Electronic Cited Medium: Internet ISSN: 2331-8422 (Electronic) Linking ISSN: 23318422 NLM ISO Abbreviation: ArXiv Subsets: PubMed not MEDLINE

Defining and benchmarking open problems in single-cell analysis.

Authors: Luecken MD Gigante S Burkhardt DB et al.

Corporate Authors: Luecken MD Gigante S Burkhardt DB et al.

Source: Research square [Res Sq] 2024 Apr 04. Date of Electronic Publication: 2024 Apr 04.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE

Publisher Correction: MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors.

Authors: Chen X Burkhardt DB Hartman AA et al.

Source: Nature communications [Nat Commun] 2020 Jan 29; Vol. 11 (1), pp. 681. Date of Electronic Publication: 2020 Jan 29.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE; PubMed not MEDLINE

MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors.

Authors: Chen X Burkhardt DB Hartman AA et al.

Source: Nature communications [Nat Commun] 2019 Dec 18; Vol. 10 (1), pp. 5767. Date of Electronic Publication: 2019 Dec 18.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Immune cells and their inflammatory mediators modify β cells and cause checkpoint inhibitor-induced diabetes.

Authors: Perdigoto AL Deng S Du KC et al.

Source: JCI insight [JCI Insight] 2022 Sep 08; Vol. 7 (17). Date of Electronic Publication: 2022 Sep 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

Mapping Phenotypic Plasticity upon the Cancer Cell State Landscape Using Manifold Learning.

Authors: Burkhardt DB San Juan BP Lock JG et al.

Source: Cancer discovery [Cancer Discov] 2022 Aug 05; Vol. 12 (8), pp. 1847-1859.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

Generating hard-to-obtain information from easy-to-obtain information: Applications in drug discovery and clinical inference.

Authors: Amodio M Shung D Burkhardt DB et al.

Source: Patterns (New York, N.Y.) [Patterns (N Y)] 2021 Jun 17; Vol. 2 (7), pp. 100288. Date of Electronic Publication: 2021 Jun 17 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101767765 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-3899 (Electronic) Linking ISSN: 26663899 NLM ISO Abbreviation: Patterns (N Y) Subsets: PubMed not MEDLINE