Search Results - "Burkhart DL"

EZH2-TTP-mTORC1 Axis Drives Phenotypic Plasticity and Therapeutic Vulnerability in Lethal Prostate Cancer.

Authors: German B Morel KL Noel T et al.

Source: Research square [Res Sq] 2025 Aug 21. Date of Electronic Publication: 2025 Aug 21.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE

EZH2-TTP-mTORC1 Axis Drives Phenotypic Plasticity and Therapeutic Vulnerability in Lethal Prostate Cancer.

Authors: German B Morel KL Noel T et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Aug 11. Date of Electronic Publication: 2025 Aug 11.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

The network response to Egf is tissue-specific.

Authors: Awasthi BW Paulo JA Burkhart DL et al.

Source: IScience [iScience] 2025 Mar 04; Vol. 28 (4), pp. 112146. Date of Electronic Publication: 2025 Mar 04 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice.

Authors: Morel KL Germán B Hamid AA et al.

Source: The Journal of clinical investigation [J Clin Invest] 2024 Nov 19; Vol. 135 (2). Date of Electronic Publication: 2024 Nov 19.

Publication Type: Journal Article

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

MYBL2 Drives Prostate Cancer Plasticity: Inhibiting Its Transcriptional Target CDK2 for RB1-Deficient Neuroendocrine Prostate Cancer.

Authors: German B Alaiwi SA Ho KL et al.

Source: Cancer research communications [Cancer Res Commun] 2024 Sep 01; Vol. 4 (9), pp. 2295-2307.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE

MYBL2 drives prostate cancer plasticity and identifies CDK2 as a therapeutic vulnerability in RB1-loss and neuroendocrine prostate cancer.

Authors: German B Singh JN Fonseca MA et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Feb 02. Date of Electronic Publication: 2024 Feb 02.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

In vivo imaging using surface enhanced spatially offset raman spectroscopy (SESORS): balancing sampling frequency to improve overall image acquisition.

Authors: Nicolson F Andreiuk B Lee E et al.

Source: Npj imaging [Npj Imaging] 2024; Vol. 2 (1). Date of Electronic Publication: 2024 Apr 03.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group UK Country of Publication: Switzerland NLM ID: 9918733285306676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2948-197X (Electronic) Linking ISSN: 2948197X NLM ISO Abbreviation: Npj Imaging Subsets: PubMed not MEDLINE

Prostate lineage-specific metabolism governs luminal differentiation and response to antiandrogen treatment.

Authors: Giafaglione JM Crowell PD Delcourt AML et al.

Source: Nature cell biology [Nat Cell Biol] 2023 Dec; Vol. 25 (12), pp. 1821-1832. Date of Electronic Publication: 2023 Dec 04.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE

Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity.

Authors: Bywater MJ Burkhart DL Straube J et al.

Source: Nature communications [Nat Commun] 2020 Apr 14; Vol. 11 (1), pp. 1827. Date of Electronic Publication: 2020 Apr 14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Classification of KRAS-Activating Mutations and the Implications for Therapeutic Intervention.

Authors: Johnson C Burkhart DL Haigis KM

Source: Cancer discovery [Cancer Discov] 2022 Apr 01; Vol. 12 (4), pp. 913-923.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

EZH2 inhibition activates a dsRNA-STING-interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer.

Authors: Morel KL Sheahan AV Burkhart DL et al.

Source: Nature cancer [Nat Cancer] 2021 Apr; Vol. 2 (4), pp. 444-456. Date of Electronic Publication: 2021 Mar 22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer

Evidence that EZH2 Deregulation is an Actionable Therapeutic Target for Prevention of Prostate Cancer.

Authors: Burkhart DL Morel KL Wadosky KM et al.

Source: Cancer prevention research (Philadelphia, Pa.) [Cancer Prev Res (Phila)] 2020 Dec; Vol. 13 (12), pp. 979-988. Date of Electronic Publication: 2020 Sep 11.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101479409 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1940-6215 (Electronic) Linking ISSN: 19406215 NLM ISO Abbreviation: Cancer Prev Res (Phila) Subsets: MEDLINE

Myc linked to dysregulation of cholesterol transport and storage in nonsmall cell lung cancer.

Authors: Hall Z Wilson CH Burkhart DL et al.

Source: Journal of lipid research [J Lipid Res] 2020 Nov; Vol. 61 (11), pp. 1390-1399. Date of Electronic Publication: 2020 Aug 04.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0376606 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-7262 (Electronic) Linking ISSN: 00222275 NLM ISO Abbreviation: J Lipid Res Subsets: MEDLINE

Tandem E2F binding sites in the promoter of the p107 cell cycle regulator control p107 expression and its cellular functions.

Authors: Burkhart DL Wirt SE Zmoos AF et al.

Source: PLoS genetics [PLoS Genet] 2010 Jun 24; Vol. 6 (6), pp. e1001003. Date of Electronic Publication: 2010 Jun 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: Electronic Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

Cellular mechanisms of tumour suppression by the retinoblastoma gene.

Authors: Burkhart DL Sage J

Source: Nature reviews. Cancer [Nat Rev Cancer] 2008 Sep; Vol. 8 (9), pp. 671-82.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124168 Publication Model: Print Cited Medium: Internet ISSN: 1474-1768 (Electronic) Linking ISSN: 1474175X NLM ISO Abbreviation: Nat Rev Cancer Subsets: MEDLINE

The Role of RB in Prostate Cancer Progression.

Authors: Burkhart DL Morel KL Sheahan AV et al.

Source: Advances in experimental medicine and biology [Adv Exp Med Biol] 2019; Vol. 1210, pp. 301-318.

Publication Type: Journal Article; Review

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 0121103 Publication Model: Print Cited Medium: Print ISSN: 0065-2598 (Print) Linking ISSN: 00652598 NLM ISO Abbreviation: Adv Exp Med Biol Subsets: MEDLINE

Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.

Authors: Kortlever RM Sodir NM Wilson CH et al.

Source: Cell [Cell] 2017 Nov 30; Vol. 171 (6), pp. 1301-1315.e14.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Determination of the physiological and pathological roles of E2F3 in adult tissues.

Authors: Gamper I Burkhart DL Bywater MJ et al.

Source: Scientific reports [Sci Rep] 2017 Aug 30; Vol. 7 (1), pp. 9932. Date of Electronic Publication: 2017 Aug 30.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Myc Expression Drives Aberrant Lipid Metabolism in Lung Cancer.

Authors: Hall Z Ament Z Wilson CH et al.

Source: Cancer research [Cancer Res] 2016 Aug 15; Vol. 76 (16), pp. 4608-18. Date of Electronic Publication: 2016 Jun 22.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Loss of p130 accelerates tumor development in a mouse model for human small-cell lung carcinoma.

Authors: Schaffer BE Park KS Yiu G et al.

Source: Cancer research [Cancer Res] 2010 May 15; Vol. 70 (10), pp. 3877-83. Date of Electronic Publication: 2010 Apr 20.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE