Search Results - "Burkin DJ"

A molecular makeover of laminin-α4 with linker proteins to mimic the function of laminin-α2 for the treatment of LAMA2-CMD.

Authors: Hermann HJ McDermott S Burkin DJ

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 May 06; Vol. 34 (5), pp. 2544-2546. Date of Electronic Publication: 2026 Apr 15.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE; In Process

Spatial proteomics reveals recombinant human laminin-111 restores adhesion signaling to laminin-α2-deficient muscle.

Authors: Hermann HJ Wuebbles RD Dagda M et al.

Source: JCI insight [JCI Insight] 2025 Oct 16; Vol. 10 (22). Date of Electronic Publication: 2025 Oct 16 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

Integrin α7 Mutations Are Associated With Adult-Onset Cardiac Dysfunction in Humans and Mice.

Authors: Bugiardini E Nunes AM Oliveira-Santos A et al.

Source: Journal of the American Heart Association [J Am Heart Assoc] 2022 Dec 06; Vol. 11 (23), pp. e026494. Date of Electronic Publication: 2022 Nov 29.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE

Sunitinib inhibits STAT3 phosphorylation in cardiac muscle and prevents cardiomyopathy in the mdx mouse model of Duchenne muscular dystrophy.

Authors: Oliveira-Santos A Dagda M Burkin DJ

Source: Human molecular genetics [Hum Mol Genet] 2022 Jul 21; Vol. 31 (14), pp. 2358-2369.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

Tetrahydrobiopterin shifts the balance from oxidative stress to NO signalling in Duchenne muscular dystrophy.

Authors: Wuebbles RD Oliveira-Santos A Burkin DJ

Source: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2021 Jul; Vol. 232 (3), pp. e13675. Date of Electronic Publication: 2021 May 26.

Publication Type: Editorial; Comment

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262545 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1748-1716 (Electronic) Linking ISSN: 17481708 NLM ISO Abbreviation: Acta Physiol (Oxf) Subsets: MEDLINE

Laminin-111 Improves the Anabolic Response to Mechanical Load in Aged Skeletal Muscle.

Authors: Garg K Mahmassani ZS Dvoretskiy S et al.

Source: The journals of gerontology. Series A, Biological sciences and medical sciences [J Gerontol A Biol Sci Med Sci] 2021 Mar 31; Vol. 76 (4), pp. 586-590.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: published on behalf of the Gerontological Society of America by Oxford University Press Country of Publication: United States NLM ID: 9502837 Publication Model: Print Cited Medium: Internet ISSN: 1758-535X (Electronic) Linking ISSN: 10795006 NLM ISO Abbreviation: J Gerontol A Biol Sci Med Sci Subsets: MEDLINE

Laminin-111 protein therapy after disease onset slows muscle disease in a mouse model of laminin-α2 related congenital muscular dystrophy.

Authors: Barraza-Flores P Bukovec KE Dagda M et al.

Source: Human molecular genetics [Hum Mol Genet] 2020 Aug 03; Vol. 29 (13), pp. 2162-2170.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

Laminin and Integrin in LAMA2-Related Congenital Muscular Dystrophy: From Disease to Therapeutics.

Authors: Barraza-Flores P Bates CR Oliveira-Santos A et al.

Source: Frontiers in molecular neuroscience [Front Mol Neurosci] 2020 Feb 11; Vol. 13, pp. 1. Date of Electronic Publication: 2020 Feb 11 (Print Publication: 2020).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477914 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5099 (Print) Linking ISSN: 16625099 NLM ISO Abbreviation: Front Mol Neurosci Subsets: PubMed not MEDLINE

Laminin-111 protein therapy enhances muscle regeneration and repair in the GRMD dog model of Duchenne muscular dystrophy.

Authors: Barraza-Flores P Fontelonga TM Wuebbles RD et al.

Source: Human molecular genetics [Hum Mol Genet] 2019 Aug 15; Vol. 28 (16), pp. 2686-2695.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy.

Authors: Oliveira-Santos A Dagda M Wittmann J et al.

Source: Disease models & mechanisms [Dis Model Mech] 2023 Jun 01; Vol. 16 (6). Date of Electronic Publication: 2023 May 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101483332 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1754-8411 (Electronic) Linking ISSN: 17548403 NLM ISO Abbreviation: Dis Model Mech Subsets: MEDLINE

A gene therapy approach for the treatment of limb-girdle muscular dystrophy 2C/R5.

Authors: Hermann H Wuebbles RD Burkin DJ

Source: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2023 Mar 30; Vol. 29, pp. 160-161. Date of Electronic Publication: 2023 Mar 30 (Print Publication: 2023).

Publication Type: News

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101624857 Publication Model: eCollection Cited Medium: Print ISSN: 2329-0501 (Print) Linking ISSN: 23290501 NLM ISO Abbreviation: Mol Ther Methods Clin Dev Subsets: PubMed not MEDLINE

The alpha7 integrin subunit in astrocytes promotes endothelial blood-brain barrier integrity.

Authors: Chen Z Kelly JR Morales JE et al.

Source: Development (Cambridge, England) [Development] 2023 Mar 15; Vol. 150 (6). Date of Electronic Publication: 2023 Mar 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

Sunitinib promotes myogenic regeneration and mitigates disease progression in the mdx mouse model of Duchenne muscular dystrophy.

Authors: Fontelonga TM Jordan B Nunes AM et al.

Source: Human molecular genetics [Hum Mol Genet] 2019 Jul 01; Vol. 28 (13), pp. 2120-2132.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

Transgenic overexpression of α7 integrin in smooth muscle attenuates allergen-induced airway inflammation in a murine model of asthma.

Authors: Ba MA Aiyuk A Hernández K et al.

Source: FASEB bioAdvances [FASEB Bioadv] 2022 Sep 12; Vol. 4 (11), pp. 724-740. Date of Electronic Publication: 2022 Sep 12 (Print Publication: 2022).

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101733210 Publication Model: eCollection Cited Medium: Internet ISSN: 2573-9832 (Electronic) Linking ISSN: 25739832 NLM ISO Abbreviation: FASEB Bioadv Subsets: PubMed not MEDLINE

Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.

Authors: Nunes AM Wuebbles RD Sarathy A et al.

Source: Human molecular genetics [Hum Mol Genet] 2017 Jun 01; Vol. 26 (11), pp. 2018-2033.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

PTRH2 gene mutation causes progressive congenital skeletal muscle pathology.

Authors: Doe J Kaindl AM Jijiwa M et al.

Source: Human molecular genetics [Hum Mol Genet] 2017 Apr 15; Vol. 26 (8), pp. 1458-1464.

Publication Type: Journal Article

Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

Mesothelioma cells breaking bad: loss of integrin α7 promotes cell motility and poor clinical outcomes in patients.

Authors: Burkin DJ Fontelonga TM

Source: The Journal of pathology [J Pathol] 2015 Nov; Vol. 237 (3), pp. 282-4. Date of Electronic Publication: 2015 Aug 26.

Publication Type: Journal Article; Comment

Journal Info: Publisher: John Wiley And Sons Country of Publication: England NLM ID: 0204634 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9896 (Electronic) Linking ISSN: 00223417 NLM ISO Abbreviation: J Pathol Subsets: MEDLINE

Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy.

Authors: Van Ry PM Wuebbles RD Key M et al.

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2015 Aug; Vol. 23 (8), pp. 1285-1297. Date of Electronic Publication: 2015 Jun 08.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

A retooled drug that restores ionic balance and cardiac function in dystrophin deficient hearts.

Authors: Wuebbles RD Burkin DJ

Source: International journal of cardiology [Int J Cardiol] 2020 Nov 15; Vol. 319, pp. 115-116. Date of Electronic Publication: 2020 Jun 03.

Publication Type: Editorial; Comment

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE

Sarcospan integration into laminin-binding adhesion complexes that ameliorate muscular dystrophy requires utrophin and α7 integrin.

Authors: Marshall JL Oh J Chou E et al.

Source: Human molecular genetics [Hum Mol Genet] 2015 Apr 01; Vol. 24 (7), pp. 2011-22. Date of Electronic Publication: 2014 Dec 11.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE