Search Results - "Burlein C"

Structure and flexibility of the DNA polymerase holoenzyme of vaccinia virus.

Authors: Burmeister, Wim P. Boutin, Laetitia Balestra, Aurelia C. et al.

Source: PLoS Pathogens. 5/20/2024, Vol. 20 Issue 5, p1-22. 22p.

Analysis of SalHV-1 Genes by Structure Prediction and Comparison Shows an Expanded Core Gene Set of the Order Herpesvirales.

Authors: Roller, Richard J. Martí-Carreras, Joan Maes, Piet

Source: Viruses (1999-4915). Mar2026, Vol. 18 Issue 3, p372. 22p.

Synthesis of novel azasugar-containing 2'β-C-Me 9-deaza nucleosides as potential anti-hepatitis C virus agents.

Authors: Kotian, Pravin L. Wu, Minwan Ghosh, Ajit et al.

Source: Nucleosides, Nucleotides & Nucleic Acids. 2023, Vol. 42 Issue 4, p317-327. 11p.

Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure-Activity Relationships.

Authors: Plotkin MA Labroli M Schubert J et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2024 Jul 09; Vol. 15 (8), pp. 1232-1241. Date of Electronic Publication: 2024 Jul 09 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

The Integrase: An Overview of a Key Player Enzyme in the Antiviral Scenario.

Authors: Renzi, Gioele Carta, Fabrizio Supuran, Claudiu T.

Source: International Journal of Molecular Sciences. Aug2023, Vol. 24 Issue 15, p12187. 22p.

Fluorinated Isoindolinone-Based Glucosylceramide Synthase Inhibitors with Low Human Dose Projections.

Authors: Loughran HM Schirripa KM Roecker AJ et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2023 Dec 21; Vol. 15 (1), pp. 123-131. Date of Electronic Publication: 2023 Dec 21 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

Discovery of arylsulfonamides as a novel class of allosteric integrase inhibitors with antiviral activity.

Authors: Wang C Adam GC Burlein C et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2023 Jun 01; Vol. 89, pp. 129303. Date of Electronic Publication: 2023 May 03.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor Interaction.

Authors: Beshore DC Adam GC Barnard RJO et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2021 Mar 07; Vol. 12 (4), pp. 540-547. Date of Electronic Publication: 2021 Mar 07 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

Pyrazole Ureas as Low Dose, CNS Penetrant Glucosylceramide Synthase Inhibitors for the Treatment of Parkinson's Disease.

Authors: Roecker AJ Schirripa KM Loughran HM et al.

Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2023 Jan 12; Vol. 14 (2), pp. 146-155. Date of Electronic Publication: 2023 Jan 12 (Print Publication: 2023).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE

Expanding Heteroaromatic and 2-Aminosugar Chemical Space Accessible from the Biopolymer Chitin.

Authors: Rossa, Thaís A. Neville, Jessica C. Jun, Seongmin Paul et al.

Source: Chemistry (2624-8549). Sep2023, Vol. 5 Issue 3, p1998-2008. 11p.

Complete and Prolonged Inhibition of Herpes Simplex Virus Type 1 Infection In Vitro by CRISPR/Cas9 and CRISPR/CasX Systems.

Authors: Karpov, Dmitry S. Demidova, Natalia A. Kulagin, Kirill A. et al.

Source: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 23, p14847. 16p.

Asymmetric Synthesis of Cyclopropyl-fused 2'-C-Methylcarbanucleosides as Potential Anti-HCV Agents.

Authors: Jeong, LakShin Lee, JeongA. Kim, HeaOk et al.

Source: Nucleosides, Nucleotides & Nucleic Acids. Aug2007, Vol. 26 Issue 8/9, p1021-1024. 4p. 3 Diagrams.

Progress in the Stereoselective Synthesis Methods of Pyrrolidine-Containing Drugs and Their Precursors.

Authors: Smolobochkin, Andrey Gazizov, Almir Appazov, Nurbol et al.

Source: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 20, p11158. 27p.

Pharmacophore-Assisted Covalent Docking Identifies a Potential Covalent Inhibitor for Drug-Resistant Genotype 3 Variants of Hepatitis C Viral NS3/4A Serine Protease.

Authors: Iman, Kanzal Mirza, Muhammad Usman Sadia, Fazila et al.

Source: Viruses (1999-4915). Aug2024, Vol. 16 Issue 8, p1250. 28p.

Investigating Potential Cancer Therapeutics: Insight into Histone Deacetylases (HDACs) Inhibitions.

Authors: Ahmad, Basharat Saeed, Aamir Al-Amery, Ahmed et al.

Source: Pharmaceuticals (14248247). Apr2024, Vol. 17 Issue 4, p444. 23p.

VSpipe-GUI, an Interactive Graphical User Interface for Virtual Screening and Hit Selection.

Authors: Hussain, Rashid Hackett, Andrew Scott Álvarez-Carretero, Sandra et al.

Source: International Journal of Molecular Sciences. Feb2024, Vol. 25 Issue 4, p2002. 16p.

2′-Modified Guanosine Analogs for the Treatment of HCV.

Authors: Girijavallabhan, Vinay Arasappan, Ashok Bennett, Frank et al.

Source: Nucleosides, Nucleotides & Nucleic Acids. 2016, Vol. 35 Issue 6, p277-294. 18p.

Research Progress in HIV and Mycobacterium tuberculosis Inhibitors Containing Sulfonamide Moiety.

Authors: Salubi, Christiana Abimbola¹ (AUTHOR)

Source: Journal of Chemistry. 12/7/2023, p1-22. 22p.

Synthesis And Anti-Hcv Activity Of 2''-β-Hydroxymethylated Nucleosides.

Authors: Jeong, LakShin Yoo, ByulNae Kim, HeaOk et al.

Source: Nucleosides, Nucleotides & Nucleic Acids. Jun2007, Vol. 26 Issue 6/7, p725-728. 4p. 4 Diagrams.

Design and Synthesis of Novel 5-((3-(Trifluoromethyl)piperidin-1-yl)sulfonyl)indoline-2,3-dione Derivatives as Promising Antiviral Agents: In Vitro, In Silico, and Structure–Activity Relationship Studies.

Authors: Ezz Eldin, Rogy R. Saleh, Marwa A. Alwarsh, Sefat A. et al.

Source: Pharmaceuticals (14248247). Sep2023, Vol. 16 Issue 9, p1247. 24p.