Search Results - "Burris, Thomas P."

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REV-ERB and ROR nuclear receptors as drug targets.

Authors: Kojetin, Douglas J. Burris, Thomas P.

Source: Nature Reviews Drug Discovery. Mar2014, Vol. 13 Issue 3, p197-216. 20p. 6 Diagrams, 3 Charts, 1 Graph.

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists.

Authors: Solt, Laura A. Wang, Yongjun Banerjee, Subhashis et al.

Source: Nature. 5/3/2012, Vol. 485 Issue 7396, p62-68. 7p.

Subjects: Circadian rhythms, Metabolic disorders, Cardiovascular system abnormality prevention, Skeletal muscle, Adipose tissues, Substance P, Laboratory mice, Chemical agonists

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Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand.

Authors: Solt, Laura A. Kumar, Naresh Nuhant, Philippe et al.

Source: Nature. 4/28/2011, Vol. 472 Issue 7344, p491-494. 4p. 4 Graphs.

Subjects: Interleukins, Nuclear receptors (Biochemistry), Cytokines, Autoimmune disease treatment, Acetamide, Cell differentiation, T-cell receptor genes, Therapeutics

Direct Regulation of CLOCK Expression by REV-ERB.

Authors: Crumbley, Christine Burris, Thomas P.

Source: PLoS ONE. 2011, Vol. 6 Issue 3, p1-6. 6p.

STL1267 inhibits myofibroblast differentiation in a TGFβ1-driven human lung fibroblast model.

Authors: Prasad, Chandrashekhar Huang, Steven K. Burris, Thomas P. et al.

Source: American Journal of Physiology: Cell Physiology. Mar2026, Vol. 330 Issue 3, p1-19. 19p.

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA.

Authors: Chandra, Vikas Huang, Pengxiang Hamuro, Yoshitomo et al.

Source: Nature. 11/20/2008, Vol. 456 Issue 7220, p350-356. 7p. 5 Diagrams.

Subjects: Molecular structure, Nuclear receptors (Biochemistry), Gene expression, Transcription factors, Ligand binding (Biochemistry), DNA-binding proteins, Peroxisomes, Scientific method

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COMPLEX GLYCEROL KINASE DEFICIENCY: A CONTIGUOUS GENE SYNDROME INVOLVING THE DUCHENNE MUSCULAR DYSTROPHY, GLYCEROL KINASE, AND ADRENAL HYPOPLASIA CONGENITA LOCI.

Authors: McCabe, Edward R. B. Guo, Weiwen Burris, Thomas P.

Source: Mental Retardation & Developmental Disabilities Research Reviews. 1996, Vol. 2 Issue 3, p160-166. 7p.

Subjects: Genetic disorders, Duchenne muscular dystrophy, Glyceryl ethers, Molecular cloning, Genes, Adrenaline

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Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease.

Authors: Griffett, Kristine Burris, Thomas P.

Source: Biochemical & Biophysical Research Communications. Oct2016, Vol. 479 Issue 3, p424-428. 5p.

Unique Ligand Binding Patterns between Estrogen Receptor α and β Revealed by HydrogenβDeuterium Exchange.

Authors: Dai, Susie Y. Burris, Thomas P. Dodge, Jeffrey A. et al.

Source: Biochemistry. 10/13/2009, Vol. 48 Issue 40, p9668-9676. 9p.

Subjects: Mass spectrometry, Ligand binding (Biochemistry), Quantum perturbations, Chemical structure, Physical & theoretical chemistry

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