Search Results - "Burstein, E. S."

The role of M1 muscarinic receptor agonism ofN-desmethylclozapine in the unique clinical effects of clozapine.

Authors: Weiner, D. M. Meltzer, H. Y. Veinbergs, I. et al.

Source: Psychopharmacology. 2004, Vol. 177 Issue 1/2, p207-216. 10p. 1 Color Photograph, 3 Charts, 2 Graphs.

Subjects: Muscarinic receptors, Cholinergic receptors, Clozapine, Antidepressants, Schizophrenia

Pimavanserin augments the efficacy of atypical antipsychotic drugs in a mouse model of treatment-refractory negative symptoms of schizophrenia.

Authors: Rajagopal L Ryan C Elzokaky A et al.

Source: Behavioural brain research [Behav Brain Res] 2022 Mar 26; Vol. 422, pp. 113710. Date of Electronic Publication: 2021 Dec 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7549 (Electronic) Linking ISSN: 01664328 NLM ISO Abbreviation: Behav Brain Res Subsets: MEDLINE

The ras-related GTPase rac1 regulates a proliferative pathway selectively utilized by G-protein coupled receptors.

Authors: Burstein ES Hesterberg DJ Gutkind JS et al.

Source: Oncogene [Oncogene] 1998 Sep 24; Vol. 17 (12), pp. 1617-23.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232 (Print) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

In vitro pharmacology of clinically used central nervous system-active drugs as inverse H(1) receptor agonists.

Authors: Bakker RA Nicholas MW Smith TT et al.

Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2007 Jul; Vol. 322 (1), pp. 172-9. Date of Electronic Publication: 2007 Apr 02.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0022-3565 (Print) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist.

Authors: Burstein ES Ma J Wong S et al.

Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2005 Dec; Vol. 315 (3), pp. 1278-87. Date of Electronic Publication: 2005 Aug 31.

Publication Type: Comparative Study; Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0022-3565 (Print) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

Molecular cloning and pharmacology of functionally distinct isoforms of the human histamine H(3) receptor.

Authors: Wellendorph P Goodman MW Burstein ES et al.

Source: Neuropharmacology [Neuropharmacology] 2002 Jun; Vol. 42 (7), pp. 929-40.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print Cited Medium: Print ISSN: 0028-3908 (Print) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

5-hydroxytryptamine2A receptor inverse agonists as antipsychotics.

Authors: Weiner DM Burstein ES Nash N et al.

Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2001 Oct; Vol. 299 (1), pp. 268-76.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0376362 Publication Model: Print Cited Medium: Print ISSN: 0022-3565 (Print) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

Constitutively active muscarinic receptors.

Authors: Spalding TA Burstein ES

Source: Life sciences [Life Sci] 2001 Apr 27; Vol. 68 (22-23), pp. 2511-6.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print Cited Medium: Print ISSN: 0024-3205 (Print) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE

Functional importance of the Ala(116)-Pro(136) region in the calcium-sensing receptor. Constitutive activity and inverse agonism in a family C G-protein-coupled receptor.

Authors: Jensen AA Spalding TA Burstein ES et al.

Source: The Journal of biological chemistry [J Biol Chem] 2000 Sep 22; Vol. 275 (38), pp. 29547-55.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling.

Authors: Burstein ES Spalding TA Brann MR

Source: The Journal of biological chemistry [J Biol Chem] 1998 Sep 18; Vol. 273 (38), pp. 24322-7.

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Identification of a ligand-dependent switch within a muscarinic receptor.

Authors: Spalding TA Burstein ES Henderson SC et al.

Source: The Journal of biological chemistry [J Biol Chem] 1998 Aug 21; Vol. 273 (34), pp. 21563-8.

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Structure/function relationships of a G-protein coupling pocket formed by the third intracellular loop of the m5 muscarinic receptor.

Authors: Burstein ES Spalding TA Brann MR

Source: Biochemistry [Biochemistry] 1998 Mar 24; Vol. 37 (12), pp. 4052-8.

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN: 0006-2960 (Print) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

Constitutive activation of the m5 muscarinic receptor by a series of mutations at the extracellular end of transmembrane 6.

Authors: Spalding TA Burstein ES Wells JW et al.

Source: Biochemistry [Biochemistry] 1997 Aug 19; Vol. 36 (33), pp. 10109-16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print Cited Medium: Print ISSN: 0006-2960 (Print) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

Pharmacology of muscarinic receptor subtypes constitutively activated by G proteins.

Authors: Burstein ES Spalding TA Brann MR

Source: Molecular pharmacology [Mol Pharmacol] 1997 Feb; Vol. 51 (2), pp. 312-9.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print Cited Medium: Print ISSN: 0026-895X (Print) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE

Interactions of muscarinic receptors with the heterotrimeric G proteins Gq and G12: transduction of proliferative signals.

Authors: Burstein ES Bräuner-Osborne H Spalding TA et al.

Source: Journal of neurochemistry [J Neurochem] 1997 Feb; Vol. 68 (2), pp. 525-33.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print Cited Medium: Print ISSN: 0022-3042 (Print) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

Use of random-saturation mutagenesis to study receptor-G protein coupling.

Authors: Burstein ES Spalding TA Brann MR

Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 1997; Vol. 83, pp. 143-57.

Publication Type: Journal Article; Review

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Print ISSN: 1064-3745 (Print) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

Constitutive activation of chimeric m2/m5 muscarinic receptors and delineation of G-protein coupling selectivity domains.

Authors: Burstein ES Spalding TA Brann MR

Source: Biochemical pharmacology [Biochem Pharmacol] 1996 Feb 23; Vol. 51 (4), pp. 539-44.

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print Cited Medium: Print ISSN: 0006-2952 (Print) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

Structure of a G-protein-coupling domain of a muscarinic receptor predicted by random saturation mutagenesis.

Authors: Hill-Eubanks D Burstein ES Spalding TA et al.

Source: The Journal of biological chemistry [J Biol Chem] 1996 Feb 09; Vol. 271 (6), pp. 3058-65.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Amino acid side chains that define muscarinic receptor/G-protein coupling. Studies of the third intracellular loop.

Authors: Burstein ES Spalding TA Brann MR

Source: The Journal of biological chemistry [J Biol Chem] 1996 Feb 09; Vol. 271 (6), pp. 2882-5.

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Pharmacology of a constitutively active muscarinic receptor generated by random mutagenesis.

Authors: Spalding TA Burstein ES Brauner-Osborne H et al.

Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 1995 Dec; Vol. 275 (3), pp. 1274-9.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0376362 Publication Model: Print Cited Medium: Print ISSN: 0022-3565 (Print) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE