Search Results - "Burstein ES"

Discovery of novel SSRIs for a combination-treatment with pimavanserin.

Authors: Kers A Gabos B Borhade S et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2026 Aug; Vol. 137, pp. 130662. Date of Electronic Publication: 2026 Apr 17.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

Nonclinical Characterization of ACP-204, a Novel Selective 5-HT2A Receptor Inverse Agonist.

Authors: Burstein ES Olsson R Skold N et al.

Source: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2026 Jun; Vol. 393 (6), pp. 104932. Date of Electronic Publication: 2026 May 05.

Publication Type: Journal Article

Journal Info: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: Netherlands NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

Imaging the 5-HT2C receptor with PET: Evaluation of 5-HT2C and 5-HT2A affinity of pimavanserin in the primate brain.

Authors: Ridler K Rizzo G Burstein ES et al.

Source: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2025 Feb; Vol. 45 (2), pp. 352-364. Date of Electronic Publication: 2024 Aug 21.

Publication Type: Journal Article

Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE

Discovery of VU6052254: A Novel, Potent M1 Positive Allosteric Modulator.

Authors: Engers JL Bungard JD Presley CC et al.

Source: ACS chemical neuroscience [ACS Chem Neurosci] 2025 Dec 17; Vol. 16 (24), pp. 4741-4750. Date of Electronic Publication: 2025 Nov 26.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

5-HT 2A receptor inverse agonist attenuates morphine withdrawal syndrome and its aversiveness in rats.

Authors: Tsai PH Morales ER Reed YY et al.

Source: Behavioural pharmacology [Behav Pharmacol] 2025 Aug 01; Vol. 36 (5), pp. 234-245. Date of Electronic Publication: 2025 May 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Lippincott Williams and Wilkins Country of Publication: England NLM ID: 9013016 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-5849 (Electronic) Linking ISSN: 09558810 NLM ISO Abbreviation: Behav Pharmacol Subsets: MEDLINE

Application of Deuterium in an M1 Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422.

Authors: Engers JL Li J Han C et al.

Source: ACS chemical neuroscience [ACS Chem Neurosci] 2025 Apr 16; Vol. 16 (8), pp. 1582-1591. Date of Electronic Publication: 2025 Mar 25.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

The impact of pimavanserin on psychotic phenotypes and tau phosphorylation in the P301L/COMT- and rTg(P301L)4510 mouse models of Alzheimer's disease.

Authors: Jimenez H Adrien L Wolin A et al.

Source: Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2022 Feb 01; Vol. 8 (1), pp. e12247. Date of Electronic Publication: 2022 Feb 01 (Print Publication: 2022).

Publication Type: Journal Article

Journal Info: Publisher: Wiley on behalf of the Alzheimer's Association Country of Publication: United States NLM ID: 101650118 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-8737 (Electronic) Linking ISSN: 23528737 NLM ISO Abbreviation: Alzheimers Dement (N Y) Subsets: PubMed not MEDLINE

Relevance of 5-HT2A Receptor Modulation of Pyramidal Cell Excitability for Dementia-Related Psychosis: Implications for Pharmacotherapy.

Authors: Burstein ES; Acadia Pharmaceuticals Inc, 12830 El Camino Real, Suite 400, San Diego, CA, 92130, USA. eburstein@acadia-pharm.com.

Source: CNS drugs [CNS Drugs] 2021 Jul; Vol. 35 (7), pp. 727-741. Date of Electronic Publication: 2021 Jul 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9431220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1934 (Electronic) Linking ISSN: 11727047 NLM ISO Abbreviation: CNS Drugs Subsets: MEDLINE

Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease.

Authors: Yuede CM Wallace CE Davis TA et al.

Source: Journal of neurochemistry [J Neurochem] 2021 Mar; Vol. 156 (5), pp. 658-673. Date of Electronic Publication: 2021 Jan 10.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

Pimavanserin reverses multiple measures of anxiety in a rodent model of post-traumatic stress disorder.

Authors: Malin DH Tsai PH Campbell JR et al.

Source: European journal of pharmacology [Eur J Pharmacol] 2023 Jan 15; Vol. 939, pp. 175437. Date of Electronic Publication: 2022 Dec 09.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

Pimavanserin augments the efficacy of atypical antipsychotic drugs in a mouse model of treatment-refractory negative symptoms of schizophrenia.

Authors: Rajagopal L Ryan C Elzokaky A et al.

Source: Behavioural brain research [Behav Brain Res] 2022 Mar 26; Vol. 422, pp. 113710. Date of Electronic Publication: 2021 Dec 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7549 (Electronic) Linking ISSN: 01664328 NLM ISO Abbreviation: Behav Brain Res Subsets: MEDLINE

Dronedarone Modulates M1 and M3 Muscarinic Receptors with Subtype Selectivity, Functional Selectivity, and Probe Dependence.

Authors: Jayasuriya GM Elmslie G Burstein ES et al.

Source: Pharmacology [Pharmacology] 2017; Vol. 99 (3-4), pp. 128-138. Date of Electronic Publication: 2016 Dec 20.

Publication Type: Journal Article

Journal Info: Publisher: Karger Country of Publication: Switzerland NLM ID: 0152016 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1423-0313 (Electronic) Linking ISSN: 00317012 NLM ISO Abbreviation: Pharmacology Subsets: MEDLINE

Preclinical PET Neuroimaging of [11C]Bexarotene.

Authors: Rotstein BH Placzek MS Krishnan HS et al.

Source: Molecular imaging [Mol Imaging] 2016 Aug 23; Vol. 15. Date of Electronic Publication: 2016 Aug 23 (Print Publication: 2016).

Publication Type: Journal Article

Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101120118 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1536-0121 (Electronic) Linking ISSN: 15353508 NLM ISO Abbreviation: Mol Imaging Subsets: MEDLINE

Pimavanserin Promotes Trophic Factor Release and Protects Cultured Primary Dopaminergic Neurons Exposed to MPP+ in a GDNF-Dependent Manner.

Authors: Lavigne EG Buttigieg D Steinschneider R et al.

Source: ACS chemical neuroscience [ACS Chem Neurosci] 2021 Jun 16; Vol. 12 (12), pp. 2088-2098. Date of Electronic Publication: 2021 May 25.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE

Retrospective Chart Review on Real-World Use of Latanoprostene Bunod 0.024% in Treatment-Naïve Patients with Open-Angle Glaucoma.

Authors: Okeke CO Burstein ES Trubnik V et al.

Source: Ophthalmology and therapy [Ophthalmol Ther] 2020 Dec; Vol. 9 (4), pp. 1041-1053. Date of Electronic Publication: 2020 Oct 07.

Publication Type: Journal Article

Journal Info: Publisher: Springer Healthcare Country of Publication: England NLM ID: 101634502 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2193-8245 (Print) NLM ISO Abbreviation: Ophthalmol Ther Subsets: PubMed not MEDLINE

On the discovery and development of pimavanserin: a novel drug candidate for Parkinson's psychosis.

Authors: Hacksell U Burstein ES McFarland K et al.

Source: Neurochemical research [Neurochem Res] 2014 Oct; Vol. 39 (10), pp. 2008-17. Date of Electronic Publication: 2014 Mar 30.

Publication Type: Journal Article; Review

Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE

Design of a highly selective and potent class of non-planar estrogen receptor β agonists.

Authors: Sundén H Ma JN Hansen LK et al.

Source: ChemMedChem [ChemMedChem] 2013 Aug; Vol. 8 (8), pp. 1283-94. Date of Electronic Publication: 2013 Jun 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

Functional enhancement of AT1R potency in the presence of the TPαR is revealed by a comprehensive 7TM receptor co-expression screen.

Authors: Hansen JT Lyngsø C Speerschneider T et al.

Source: PloS one [PLoS One] 2013; Vol. 8 (3), pp. e58890. Date of Electronic Publication: 2013 Mar 14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Discovery of potential antipsychotic agents possessing pro-cognitive properties.

Authors: Lameh J McFarland K Ohlsson J et al.

Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2012 Mar; Vol. 385 (3), pp. 313-23. Date of Electronic Publication: 2011 Nov 15.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

I. In vivo evidence for partial agonist effects of (-)-OSU6162 and (+)-OSU6162 on 5-HT2A serotonin receptors.

Authors: Carlsson ML Burstein ES Kloberg A et al.

Source: Journal of neural transmission (Vienna, Austria : 1996) [J Neural Transm (Vienna)] 2011 Nov; Vol. 118 (11), pp. 1511-22. Date of Electronic Publication: 2011 Aug 28.

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer-Verlag Country of Publication: Austria NLM ID: 9702341 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-1463 (Electronic) Linking ISSN: 03009564 NLM ISO Abbreviation: J Neural Transm (Vienna) Subsets: MEDLINE