Search Results - "Capener JL"

PAK1 inhibitor NVS-PAK1-1 preserves dendritic spines in amyloid/tau exposed neurons and 5xFAD mice.

Authors: Yang T Huhe H Williams SP et al.

Corporate Authors: Yang T Huhe H Williams SP et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Dec; Vol. 21 (12), pp. e71033.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

Development of NanoBRET cellular target engagement assays in primary neurons for activating mutants of p21-activated kinase 1.

Authors: Capener JL Badillo-Martinez A Awada B et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 06. Date of Electronic Publication: 2026 May 06.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Advances in BRET probes for intracellular target engagement studies.

Authors: Capener JL Schwalm MP Vasta JD et al.

Source: Nature chemical biology [Nat Chem Biol] 2026 May; Vol. 22 (5), pp. 691-701. Date of Electronic Publication: 2026 Jan 06.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

Development of a Chemical Probe to Enable Characterization of the Casein Kinase 1γ Subfamily.

Authors: Capener JL Kramer TW Bashore FM et al.

Source: Journal of medicinal chemistry [J Med Chem] 2026 Feb 12; Vol. 69 (3), pp. 2666-2684. Date of Electronic Publication: 2026 Jan 26.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Development of a chemical probe to enable characterization of the casein kinase 1γ subfamily.

Authors: Capener JL Kramer TW Bashore FM et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Sep 16. Date of Electronic Publication: 2025 Sep 16.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Illumination of understudied ciliary kinases.

Authors: Flax RG Rosston P Rocha C et al.

Source: Frontiers in molecular biosciences [Front Mol Biosci] 2024 Mar 08; Vol. 11, pp. 1352781. Date of Electronic Publication: 2024 Mar 08 (Print Publication: 2024).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101653173 Publication Model: eCollection Cited Medium: Print ISSN: 2296-889X (Print) Linking ISSN: 2296889X NLM ISO Abbreviation: Front Mol Biosci Subsets: PubMed not MEDLINE

More than an Amide Bioisostere: Discovery of 1,2,4-Triazole-containing Pyrazolo[1,5-a]pyrimidine Host CSNK2 Inhibitors for Combatting β-Coronavirus Replication.

Authors: Ong HW Yang X Smith JL et al.

Source: Journal of medicinal chemistry [J Med Chem] 2024 Jul 25; Vol. 67 (14), pp. 12261-12313. Date of Electronic Publication: 2024 Jul 03.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Development of SYK NanoBRET Cellular Target Engagement Assays for Gain-of-Function Variants.

Authors: Capener JL Vasta JD Katis VL et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jun 13. Date of Electronic Publication: 2024 Jun 13.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits.

Authors: Arveseth CD Happ JT Hedeen DS et al.

Source: PLoS biology [PLoS Biol] 2021 Apr 22; Vol. 19 (4), pp. e3001191. Date of Electronic Publication: 2021 Apr 22 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

Development of SYK NanoBRET cellular target engagement assays for gain-of-function variants.

Authors: Capener JL Vasta JD Katis VL et al.

Source: Frontiers in chemical biology [Front Chem Biol] 2024; Vol. 3. Date of Electronic Publication: 2024 Jul 28.

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 9918716583206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2813-530X (Electronic) Linking ISSN: 2813530X NLM ISO Abbreviation: Front Chem Biol Subsets: PubMed not MEDLINE

A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction.

Authors: Happ JT Arveseth CD Bruystens J et al.

Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2022 Oct; Vol. 29 (10), pp. 990-999. Date of Electronic Publication: 2022 Oct 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE