Search Results - "Castaldi MP"

Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance.

Authors: Wrobel L Hill SM Djajadikerta A et al.

Source: Nature communications [Nat Commun] 2022 Jul 16; Vol. 13 (1), pp. 4146. Date of Electronic Publication: 2022 Jul 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Genomic Discovery and Structure-Activity Exploration of a Novel Family of Enzyme-Activated Covalent Cyclin-Dependent Kinase Inhibitors.

Authors: Davison JR Hadjithomas M Romeril SP et al.

Source: Journal of medicinal chemistry [J Med Chem] 2024 Aug 08; Vol. 67 (15), pp. 13147-13173. Date of Electronic Publication: 2024 Jul 30.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Proteolysis-targeting chimeras in drug development: A safety perspective.

Authors: Moreau K Coen M Zhang AX et al.

Source: British journal of pharmacology [Br J Pharmacol] 2020 Apr; Vol. 177 (8), pp. 1709-1718. Date of Electronic Publication: 2020 Feb 25.

Publication Type: Journal Article; Review

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners.

Authors: Doshi AS Cantin S Hernandez M et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2023 May 04; Vol. 22 (5), pp. 630-645.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

Chemical Biology Approaches Confirm MCT4 as the Therapeutic Target of a Cellular Optimized Hit.

Authors: Kawatkar A Clark RA Hopcroft L et al.

Source: ACS chemical biology [ACS Chem Biol] 2023 Feb 17; Vol. 18 (2), pp. 296-303. Date of Electronic Publication: 2023 Jan 05.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Small-molecule stabilization of the p53 - 14-3-3 protein-protein interaction.

Authors: Doveston RG Kuusk A Andrei SA et al.

Source: FEBS letters [FEBS Lett] 2017 Aug; Vol. 591 (16), pp. 2449-2457. Date of Electronic Publication: 2017 Aug 06.

Publication Type: Letter; Research Support, Non-U.S. Gov't

Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3468 (Electronic) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE

Mechanistic Insights into a CDK9 Inhibitor Via Orthogonal Proteomics Methods.

Authors: Hendricks JA Beaton N Chernobrovkin A et al.

Source: ACS chemical biology [ACS Chem Biol] 2022 Jan 21; Vol. 17 (1), pp. 54-67. Date of Electronic Publication: 2021 Dec 25.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2.

Authors: Casás-Selves M Zhang AX Dowling JE et al.

Source: ChemMedChem [ChemMedChem] 2017 Jun 21; Vol. 12 (12), pp. 917-924. Date of Electronic Publication: 2017 Apr 26.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

Advances in Protein Degradation.

Authors: Castaldi MP Fisher SL

Source: SLAS discovery : advancing life sciences R & D [SLAS Discov] 2021 Apr; Vol. 26 (4), pp. 471-473.

Publication Type: Editorial; Introductory Journal Article

Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101697563 Publication Model: Print Cited Medium: Internet ISSN: 2472-5560 (Electronic) Linking ISSN: 24725552 NLM ISO Abbreviation: SLAS Discov Subsets: MEDLINE

'Design, synthesis, and strategic use of small chemical probes toward identification of novel targets for drug development'.

Authors: Castaldi MP Hendricks JA Zhang AX

Source: Current opinion in chemical biology [Curr Opin Chem Biol] 2020 Jun; Vol. 56, pp. 91-97. Date of Electronic Publication: 2020 May 03.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9811312 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0402 (Electronic) Linking ISSN: 13675931 NLM ISO Abbreviation: Curr Opin Chem Biol Subsets: MEDLINE

Affinity-Bead Assisted Mass Spectrometry (Affi-BAMS): A Multiplexed Microarray Platform for Targeted Proteomics.

Authors: Hamza GM Bergo VB Mamaev S et al.

Source: International journal of molecular sciences [Int J Mol Sci] 2020 Mar 16; Vol. 21 (6). Date of Electronic Publication: 2020 Mar 16.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex.

Authors: Hsu JH Rasmusson T Robinson J et al.

Source: Cell chemical biology [Cell Chem Biol] 2020 Jan 16; Vol. 27 (1), pp. 41-46.e17. Date of Electronic Publication: 2019 Nov 27.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

CETSA beyond Soluble Targets: a Broad Application to Multipass Transmembrane Proteins.

Authors: Kawatkar A Schefter M Hermansson NO et al.

Source: ACS chemical biology [ACS Chem Biol] 2019 Sep 20; Vol. 14 (9), pp. 1913-1920. Date of Electronic Publication: 2019 Aug 16.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Conformational inhibition of the hepatitis C virus internal ribosome entry site RNA.

Authors: Parsons J Castaldi MP Dutta S et al.

Source: Nature chemical biology [Nat Chem Biol] 2009 Nov; Vol. 5 (11), pp. 823-5. Date of Electronic Publication: 2009 Sep 20.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6.

Authors: McCoull W Cheung T Anderson E et al.

Source: ACS chemical biology [ACS Chem Biol] 2018 Nov 16; Vol. 13 (11), pp. 3131-3141. Date of Electronic Publication: 2018 Oct 17.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Chemical Instability and Promiscuity of Arylmethylidenepyrazolinone-Based MDMX Inhibitors.

Authors: Stefaniak J Lewis AM Conole D et al.

Source: ACS chemical biology [ACS Chem Biol] 2018 Oct 19; Vol. 13 (10), pp. 2849-2854. Date of Electronic Publication: 2018 Sep 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers.

Authors: Koundinya M Sudhalter J Courjaud A et al.

Source: Cell chemical biology [Cell Chem Biol] 2018 Jun 21; Vol. 25 (6), pp. 705-717.e11. Date of Electronic Publication: 2018 Apr 05.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE

Modulating Antibody Structure and Function through Directed Mutations and Chemical Rescue.

Authors: Kaiser CE Rincon Pabon JP Khowsathit J et al.

Source: ACS synthetic biology [ACS Synth Biol] 2018 Apr 20; Vol. 7 (4), pp. 1152-1162. Date of Electronic Publication: 2018 Apr 09.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE

Hepatitis C virus translation inhibitors targeting the internal ribosomal entry site.

Authors: Dibrov SM Parsons J Carnevali M et al.

Source: Journal of medicinal chemistry [J Med Chem] 2014 Mar 13; Vol. 57 (5), pp. 1694-707. Date of Electronic Publication: 2013 Nov 05.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Review

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Stereoselective synthesis of spirocyclic oxindoles via Prins cyclizations.

Authors: Castaldi MP Troast DM Porco JA Jr

Source: Organic letters [Org Lett] 2009 Aug 06; Vol. 11 (15), pp. 3362-5.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE