Search Results - "Cluse LA"

Dual Bcl-2/Bcl-xl inhibition via AZD0466 combines with immune checkpoint blockade to enhance anti-tumour activity.

Authors: Newman DM Andersen CL Cluse LA et al.

Source: Cell death & disease [Cell Death Dis] 2026 Jan 06; Vol. 17 (1), pp. 177. Date of Electronic Publication: 2026 Jan 06.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

Enhanced efficacy of a specific HDAC3 inhibitor in combination with 5-azacitidine against diffuse large B-cell lymphoma.

Authors: Calaud C Serrano-Lopez EM Cluse LA et al.

Source: Blood neoplasia [Blood Neoplasia] 2026 Mar 02; Vol. 3 (2), pp. 100214. Date of Electronic Publication: 2026 Mar 02 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918841988906676 Publication Model: eCollection Cited Medium: Internet ISSN: 2950-3280 (Electronic) Linking ISSN: 29503280 NLM ISO Abbreviation: Blood Neoplasia Subsets: PubMed not MEDLINE

Discovery and Characterization of VPRBP/DCAF1 Kinase Inhibitor Analogs as Microtubular Destabilizing Agents with Potent Antimyeloma Activity.

Authors: Susanto O Gruber E Wun CM et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2026 Mar 02; Vol. 25 (3), pp. 416-434.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression.

Authors: Gago da Graça C Sheikh AA Newman DM et al.

Source: Science immunology [Sci Immunol] 2025 Jan 31; Vol. 10 (103), pp. eadn1945. Date of Electronic Publication: 2025 Jan 31.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE

Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML.

Authors: Salmon JM Todorovski I Stanley KL et al.

Source: Cancer discovery [Cancer Discov] 2022 Jun 02; Vol. 12 (6), pp. 1560-1579.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

BET Inhibition Enhances TNF-Mediated Antitumor Immunity.

Authors: Wellinger LC Hogg SJ Newman DM et al.

Source: Cancer immunology research [Cancer Immunol Res] 2022 Jan; Vol. 10 (1), pp. 87-107. Date of Electronic Publication: 2021 Nov 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

Authors: Hogg SJ Motorna O Cluse LA et al.

Source: Molecular cell [Mol Cell] 2021 May 20; Vol. 81 (10), pp. 2183-2200.e13.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity.

Authors: Fan Z Devlin JR Hogg SJ et al.

Source: Science advances [Sci Adv] 2020 Apr 29; Vol. 6 (18). Date of Electronic Publication: 2020 Apr 29 (Print Publication: 2020).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE; PubMed not MEDLINE

Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in T(H)1 responses.

Authors: Croker BA Handman E Hayball JD et al.

Source: Immunology and cell biology [Immunol Cell Biol] 2002 Jun; Vol. 80 (3), pp. 231-40.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 8706300 Publication Model: Print Cited Medium: Print ISSN: 0818-9641 (Print) Linking ISSN: 08189641 NLM ISO Abbreviation: Immunol Cell Biol Subsets: MEDLINE

A Comprehensive Protocol Resource for Performing Pooled shRNA and CRISPR Screens.

Authors: Cluse LA Nikolic I Knight D et al.

Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2018; Vol. 1725, pp. 201-227.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.

Authors: Hogg SJ Vervoort SJ Deswal S et al.

Source: Cell reports [Cell Rep] 2017 Feb 28; Vol. 18 (9), pp. 2162-2174.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

BET Inhibition Induces Apoptosis in Aggressive B-Cell Lymphoma via Epigenetic Regulation of BCL-2 Family Members.

Authors: Hogg SJ Newbold A Vervoort SJ et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2016 Sep; Vol. 15 (9), pp. 2030-41. Date of Electronic Publication: 2016 Jul 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.

Authors: Matthews GM Mehdipour P Cluse LA et al.

Source: Blood [Blood] 2015 Nov 19; Vol. 126 (21), pp. 2392-403. Date of Electronic Publication: 2015 Oct 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

An intact immune system is required for the anticancer activities of histone deacetylase inhibitors.

Authors: West AC Mattarollo SR Shortt J et al.

Source: Cancer research [Cancer Res] 2013 Dec 15; Vol. 73 (24), pp. 7265-76. Date of Electronic Publication: 2013 Oct 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Molecular and biologic analysis of histone deacetylase inhibitors with diverse specificities.

Authors: Newbold A Matthews GM Bots M et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2013 Dec; Vol. 12 (12), pp. 2709-21. Date of Electronic Publication: 2013 Oct 03.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

Deciphering the molecular events necessary for synergistic tumor cell apoptosis mediated by the histone deacetylase inhibitor vorinostat and the BH3 mimetic ABT-737.

Authors: Wiegmans AP Alsop AE Bots M et al.

Source: Cancer research [Cancer Res] 2011 May 15; Vol. 71 (10), pp. 3603-15. Date of Electronic Publication: 2011 Mar 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms.

Authors: Oliaro J Van Ham V Sacirbegovic F et al.

Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2010 Jul 01; Vol. 185 (1), pp. 367-75. Date of Electronic Publication: 2010 Jun 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy.

Authors: Ellis L Bots M Lindemann RK et al.

Source: Blood [Blood] 2009 Jul 09; Vol. 114 (2), pp. 380-93. Date of Electronic Publication: 2009 Apr 21.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors.

Authors: Whitecross KF Alsop AE Cluse LA et al.

Source: Blood [Blood] 2009 Feb 26; Vol. 113 (9), pp. 1982-91. Date of Electronic Publication: 2008 Dec 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin.

Authors: Newbold A Lindemann RK Cluse LA et al.

Source: Molecular cancer therapeutics [Mol Cancer Ther] 2008 May; Vol. 7 (5), pp. 1066-79.

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Print ISSN: 1535-7163 (Print) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE