Search Results - "Cookson, Mark R."

Sex effects on gene expression across the human cerebral cortex at cell type resolution.

Authors: DeCasien, Alex R. Auluck, Pavan Liu, Siyuan et al.

Source: Science. 4/16/2026, Vol. 392 Issue 6795, p1-17. 17p.

Subjects: Gene expression, Cerebral cortex, Motor neurons, Sexual dimorphism, Sex chromosomes, Cognition disorders, Neurobehavioral disorders, Transcriptomes

How Parkinson's Disease-Linked LRRK2 Mutations Affect Different CNS Cell Types.

Authors: Bailey, Hannah M. Cookson, Mark R.

Source: Journal of Parkinson's Disease. 2024, Vol. 14 Issue 7, p1331-1352. 22p.

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LRRK2 recruitment, activity, and function in organelles.

Authors: Bonet‐Ponce, Luis Cookson, Mark R.

Source: FEBS Journal. Nov2022, Vol. 289 Issue 22, p6871-6890. 20p.

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LRRK2 at the interface of autophagosomes, endosomes and lysosomes.

Authors: Roosen, Dorien A. Cookson, Mark R.

Source: Molecular Neurodegeneration. 12/7/2016, Vol. 11, p1-10. 10p. 2 Diagrams, 1 Chart.

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Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at 16q11.2 and MAPT H1 loci.

Authors: Soutar, Marc P M Melandri, Daniela O'Callaghan, Benjamin et al.

Source: Brain: A Journal of Neurology; Dec2022, Vol. 145 Issue 12, p4349-4367, 19p

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Genetic variability in the regulation of gene expression in ten regions of the human brain.

Authors: Ramasamy, Adaikalavan Trabzuni, Daniah Guelfi, Sebastian et al.

Source: Nature Neuroscience. Oct2014, Vol. 17 Issue 10, p1418-1428. 11p.

Subjects: Brain, Gene expression, Genes, Genomes, Exons (Genetics)

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mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex.

Authors: Dillman, Allissa A Hauser, David N Gibbs, J Raphael et al.

Source: Nature Neuroscience. Apr2013, Vol. 16 Issue 4, p499-506. 8p.

Subjects: Neural development, Gene expression, Nucleotide sequence, Cerebral cortex, Embryology

The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease.

Authors: Cookson, Mark R.

Source: Nature Reviews Neuroscience. Dec2010, Vol. 11 Issue 12, p791-797. 7p. 2 Diagrams.

Subjects: Leucine, Parkinson's disease & genetics, Physiological effects of proteins, Genetic mutation, Guanosine triphosphatase, Biological models, Central nervous system, Disease susceptibility, Dopamine, Nerve tissue proteins, Parkinson's disease, Transferases

α-Synuclein and neuronal cell death.

Authors: Cookson, Mark R.¹ cookson@mail.nih.gov

Source: Molecular Neurodegeneration. 2009, Vol. 4, p1-14. 14p. 1 Diagram.