Search Results - "Costas-Insua C"

Endocannabinoid Enhancement via MAGL Inhibition in CDKL5 Deficiency: Selective Cellular Benefits and Domain-Specific Functional Effects in Adult Cdkl5 KO Mice.

Authors: Loi, Manuela Mottolese, Nicola Medici, Giorgio et al.

Source: International Journal of Molecular Sciences. Mar2026, Vol. 27 Issue 6, p2773. 26p.

GAP43 Located on Corticostriatal Terminals Restrains Novelty-Induced Hyperactivity in Mice.

Authors: Maroto IB Costas-Insua C Montero-Fernández C et al.

Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2024 Sep 25; Vol. 44 (39). Date of Electronic Publication: 2024 Sep 25.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

Restoration of CB1 receptor function in hippocampal GABAergic neurons rescues memory deficits in Huntington's disease models.

Authors: Di Franco N Bengoetxea de Tena I Sanchez-Ruiz A et al.

Source: Translational neurodegeneration [Transl Neurodegener] 2025 Aug 25; Vol. 14 (1), pp. 44. Date of Electronic Publication: 2025 Aug 25.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101591861 Publication Model: Electronic Cited Medium: Print ISSN: 2047-9158 (Print) Linking ISSN: 20479158 NLM ISO Abbreviation: Transl Neurodegener Subsets: MEDLINE

Cannabidiol in Developmental Epilepsy: Organoid-Guided Precision Medicine Across Critical Neurodevelopmental Windows.

Authors: Joo, Jin Yang, Woo Sub Koh, Hyun Jung

Source: International Journal of Molecular Sciences. Mar2026, Vol. 27 Issue 6, p2899. 25p.

The endocannabinoid system in cancer biology: a mini-review of mechanisms and therapeutic potential.

Authors: Salum, Kaio Cezar Rodrigues Miranda, Gabriel Brendo Alves Dias, Alessandra Lima et al.

Source: Oncology Reviews. 2025, p1-9. 9p.

Poly-alanine-tailing is a modifier of neurodegeneration caused by Listerin mutation.

Authors: Hung HC Costas-Insua C Holbrook SE et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 24. Date of Electronic Publication: 2024 Aug 24.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

The Neuro-Melanoma Singularity: Convergent Evolution of Neural and Melanocytic Networks in Brain Metastatic Adaptation.

Authors: Atanasescu, Vlad-Petre Breazu, Alexandru Oprea, Stefan et al.

Source: Biomolecules (2218-273X). Dec2025, Vol. 15 Issue 12, p1683. 34p.

Modeling the Effect of Cannabinoid Exposure During Human Neurodevelopment Using Bidimensional and Tridimensional Cultures.

Authors: Estudillo, Enrique Castillo-Arellano, Jorge Iván Martínez, Emilio et al.

Source: Cells (2073-4409). Jan2025, Vol. 14 Issue 2, p70. 24p.

Investigating the association between the GAP-43 concentration with diffusion tensor imaging indices in Alzheimer's dementia continuum.

Authors: Ariaei, Armin Ghorbani, Atousa Habibzadeh, Elham et al.

Source: BMC Neurology. 10/17/2024, Vol. 24 Issue 1, p1-12. 12p.

Selective inhibition of cannabinoid CB1 receptor-evoked signalling by the interacting protein GAP43.

Authors: Maroto IB Moreno E Costas-Insua C et al.

Source: Neuropharmacology [Neuropharmacology] 2023 Dec 01; Vol. 240, pp. 109712. Date of Electronic Publication: 2023 Sep 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE

Chromosome duplication causes premature aging via defects in ribosome quality control.

Authors: Escalante, Leah E. Hose, James Ahrens, Jamie M. et al.

Source: PLoS Biology. 11/17/2025, Vol. 23 Issue 11, p1-27. 27p.

The Endocannabinoid System in Human Disease: Molecular Signaling, Receptor Pharmacology, and Therapeutic Innovation.

Authors: Șerban, Matei Toader, Corneliu Covache-Busuioc, Răzvan-Adrian

Source: International Journal of Molecular Sciences. Nov2025, Vol. 26 Issue 22, p11132. 37p.

Fatty Acid Amides Suppress Proliferation via Cannabinoid Receptors and Promote the Apoptosis of C6 Glioma Cells in Association with Akt Signaling Pathway Inhibition.

Authors: Silva, Nágila Monteiro da Lopes, Izabella Carla Silva Galué-Parra, Adan Jesus et al.

Source: Pharmaceuticals (14248247). Jul2024, Vol. 17 Issue 7, p873. 16p.

Mechanism and evolutionary origins of alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10.

Authors: Patil PR Burroughs AM Misra M et al.

Source: Cell reports [Cell Rep] 2023 Sep 26; Vol. 42 (9), pp. 113100. Date of Electronic Publication: 2023 Sep 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

The GRP78-PERK axis contributes to memory and synaptic impairments in Huntington's disease R6/1 mice.

Authors: Espina M Di Franco N Brañas-Navarro M et al.

Source: Neurobiology of disease [Neurobiol Dis] 2023 Aug; Vol. 184, pp. 106225. Date of Electronic Publication: 2023 Jul 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE

Inhibition of the mitochondrial pyruvate carrier attenuates the integrated stress response activation in a cellular model of Huntington's disease.

Authors: Oliveira  Almeida LM Oliveira JMA et al.

Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2026 Jul; Vol. 481 (7), pp. 2881-2894. Date of Electronic Publication: 2026 May 21.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE

PCMT1 generates the C-terminal cyclic imide degron on CRBN substrates.

Authors: Zhao Z Xu W Feng EY et al.

Source: Nature chemical biology [Nat Chem Biol] 2026 May; Vol. 22 (5), pp. 802-812. Date of Electronic Publication: 2025 Dec 29.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

Neuronal Cannabinoid CB 1 Receptors Suppress the Growth of Melanoma Brain Metastases by Inhibiting Glutamatergic Signalling.

Authors: Costas-Insua, Carlos Seijo-Vila, Marta Blázquez, Cristina et al.

Source: Cancers. May2023, Vol. 15 Issue 9, p2439. 19p.

Deciphering the Blood–Brain Barrier Paradox in Brain Metastasis Development and Therapy.

Authors: Peters, Jens Jeshu Teng, Chubei Peng, Kang et al.

Source: Cancers. Jan2025, Vol. 17 Issue 2, p298. 29p.

The Cytotoxic Effects of Cannabidiol and Cannabigerol on Glioblastoma Stem Cells May Mostly Involve GPR55 and TRPV1 Signalling.

Authors: Lah, Tamara T. Majc, Bernarda Novak, Metka et al.

Source: Cancers. Dec2022, Vol. 14 Issue 23, p5918. 21p.