Search Results - "Defelipe LA"

Sla2 is a core interaction hub for clathrin light chain and the Pan1/End3/Sla1 complex.

Authors: Draper-Barr G Defelipe LA Ruiz-Carrillo D et al.

Source: Structure (London, England : 1993) [Structure] 2025 Jul 03; Vol. 33 (7), pp. 1193-1207.e5. Date of Electronic Publication: 2025 May 09.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE

Molecular modeling of highly selective CDK1 Inhibitors based on pyrazolo-pyrimidines using 3D-QSAR, docking, and molecular dynamics simulations.

Authors: Tahir, Muhammad Afaq Chohan, Tahir Ali Qayyum, Aisha et al.

Source: PLoS ONE. 6/22/2026, Vol. 21 Issue 6, p1-26. 26p.

A novel targeting domain directs essential components of the cytosolic iron–sulfur cluster assembly pathway to the mitochondrion of Toxoplasma parasites.

Authors: Hodgson, Evie R. Hayward, Jenni A. Leonard, Rachel A. et al.

Source: PLoS Biology. 11/25/2025, Vol. 23 Issue 11, p1-39. 39p.

In silico evaluation of 4-quinolone ligands interacting with human G protein-coupled receptor kinase 5 (GRK5) using message passing neural networks (MPNNs), molecular docking, and dynamics simulation.

Authors: Anthony, Godswill Imolele Ogbozor, Festus Ikechukwu Atanda, David Ololade et al.

Source: Egyptian Journal of Medical Human Genetics. 9/22/2025, Vol. 26 Issue 1, p1-16. 16p.

Broad host range phage LPC-1 reduce the risk of Listeria monocytogenes contamination in different food matrices.

Authors: Chong, Qian Fan, Ziqiu Ma, Yonghui et al.

Source: Archives of Microbiology. Jul2025, Vol. 207 Issue 7, p1-14. 14p.

Allosteric modulation of Plasmodium falciparum Isoleucyl tRNA synthetase by South African natural compounds.

Authors: Chepsiror, Curtis Veldman, Wayde Olotu, Fisayo et al.

Source: PLoS ONE. 5/14/2025, Vol. 20 Issue 5, p1-34. 34p.

A synonymous KCNH2 polymorphism and methadone trough level influence QTc prolongation in Kelantanese Malay recipients of methadone maintenance therapy (MMT) in Malaysia.

Authors: Abdul Jalal, Muhammad Irfan Abdullah-Zawawi, Muhammad-Redha Musa, Nurfadhlina et al.

Source: PLoS ONE. 5/5/2025, Vol. 20 Issue 5, p1-22. 22p.

Omeprazole exacerbates intervertebral disc degeneration through Caspase-3 mediated apoptosis of nucleus pulposus cells: a Mendelian randomization, network toxicology, and in vitro experimental study.

Authors: Jia, Yuchao Zhao, Haifan Huang, Shengbo et al.

Source: Journal of Orthopaedic Surgery & Research. 5/3/2025, Vol. 20 Issue 1, p1-11. 11p.

Inter-organelle communication dynamically orchestrates juvenile hormone biosynthesis and female reproduction.

Authors: Zhu, Shiming Liu, Fangfang Chen, Xiaoyi et al.

Source: National Science Review. Mar2025, Vol. 12 Issue 3, p1-17. 17p.

Sex-biased juvenile hormone and gene expression underlie sex difference of stress resistance in the American cockroach.

Authors: Liu, Fangfang Zhang, Shudian Chen, Ping et al.

Source: Journal of Pest Science. Mar2025, Vol. 98 Issue 2, p973-985. 13p.

Metagenomic analysis of hot spring soil for mining a novel thermostable enzybiotic.

Authors: Pantiora, Panagiota D. Georgakis, Nikolaos D. Premetis, Georgios E. et al.

Source: Applied Microbiology & Biotechnology; 1/22/2024, Vol. 108 Issue 1, p1-20, 20p

Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97.

Authors: Bothe, Sebastian Hänzelmann, Petra Böhler, Stephan et al.

Source: Communications Chemistry. 12/7/2022, Vol. 5 Issue 1, p1-15. 15p.

Amyloid accelerator polyphosphate fits as the mystery density in α-synuclein fibrils.

Authors: Huettemann, Philipp Mahadevan, Pavithra Lempart, Justine et al.

Source: PLoS Biology. 10/31/2024, Vol. 22 Issue 10, p1-20. 20p.

Cyp6g2 is the major P450 epoxidase responsible for juvenile hormone biosynthesis in Drosophila melanogaster.

Authors: Jia, Qiangqiang Yang, Liu Wen, Jiamin et al.

Source: BMC Biology. 5/13/2024, Vol. 22 Issue 1, p1-14. 14p.

Efficacy and underlying mechanisms of the essential oil derived from Rosmarinus officinalis against Aleuroglyphus ovatus (Acari: Acaridae).

Authors: Zhang, Luoling Teng, Qiao Guo, Junjie et al.

Source: International Journal of Acarology. Apr2024, Vol. 50 Issue 3, p209-221. 13p.

Modifications of diketopiperazines assembled by cyclodipeptide synthases with cytochrome P450 enzymes.

Authors: Harken, Lauritz Li, Shu-Ming

Source: Applied Microbiology & Biotechnology; Mar2021, Vol. 105 Issue 6, p2277-2285, 9p

Evaluating the use of absolute binding free energy in the fragment optimisation process.

Authors: Alibay, Irfan Magarkar, Aniket Seeliger, Daniel et al.

Source: Communications Chemistry. 9/5/2022, Vol. 5 Issue 1, p1-13. 13p.

New molecules candidates with a semicarbazide scaffold - anticancer potential in view of research on their physicochemical properties, antioxidant activity, and preliminary biological activity.

Authors: Walczak ŁJ Arczewska M Karczmarzyk Z et al.

Source: Pharmacological reports : PR [Pharmacol Rep] 2026 Jun; Vol. 78 (3), pp. 826-848. Date of Electronic Publication: 2026 Mar 05.

Publication Type: Journal Article

Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101234999 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2299-5684 (Electronic) Linking ISSN: 17341140 NLM ISO Abbreviation: Pharmacol Rep Subsets: MEDLINE

In silico identification of promising PD-L1 inhibitors from selected indian medicinal plants for treatment of triple negative breast cancer.

Authors: Ahmed, Sk. Faisal Hossain, Md. Shohel Mondal, Amalesh et al.

Source: PLoS ONE. 7/10/2025, Vol. 20 Issue 7, p1-26. 26p.

DrugProtAI: A machine learning–driven approach for predicting protein druggability through feature engineering and robust partition-based ensemble methods.

Authors: Halder, Ankit Samantaray, Sabyasachi Barbade, Sahil et al.

Source: Briefings in Bioinformatics. Jul2025, Vol. 26 Issue 4, p1-11. 11p.