Search Results - "Digigow, Reinaldo"

Putting square pegs in round holes: Why traditional pharmacokinetic principles cannot universally be applied to iron-carbohydrate complexes.

Authors: Alston, Amy Barton Digigow, Reinaldo Flühmann, Beat et al.

Source: European Journal of Pharmaceutics & Biopharmaceutics. Jul2023, Vol. 188, p6-14. 9p.

Uptake and Intracellular Fate of Peptide Surface-Functionalized Silica Hybrid Magnetic Nanoparticles In Vitro.

Authors: Digigow, Reinaldo G. Vanhecke, Dimitri Rothen‐Rutishauser, Barbara et al.

Source: Particle & Particle Systems Characterization. Feb2015, Vol. 32 Issue 2, p188-196. 9p.

Sulfide silver autometallography to differentiate the ultrastructural localization of iron-carbohydrate complexes inside macrophages.

Authors: Cao, Anne-Marinette Duruz, Jules de Almeida, Mauro Sousa et al.

Source: Scientific Reports. 12/8/2025, Vol. 15 Issue 1, p1-11. 11p.

Preparation and characterization of functional silica hybrid magnetic nanoparticles.

Authors: Digigow, Reinaldo G. Dechézelles, Jean-François Dietsch, Hervé et al.

Source: Journal of Magnetism & Magnetic Materials. Aug2014, Vol. 362, p72-79. 8p.

Subjects: Chemical sample preparation, Silica, Magnetic nanoparticles, Ethyl silicate, Amino group, Superparamagnetic materials

Magnetic Nanoparticles: Uptake and Intracellular Fate of Peptide Surface-Functionalized Silica Hybrid Magnetic Nanoparticles In Vitro (Part. Part. Syst. Charact. 2/2015).

Authors: Digigow, Reinaldo G. Vanhecke, Dimitri Rothen‐Rutishauser, Barbara et al.

Source: Particle & Particle Systems Characterization. Feb2015, Vol. 32 Issue 2, p135-135. 1p.

Challenging Traditional ADME Assumptions for Physiologically Based Pharmacokinetic Models for Intravenous Administration of Iron–Carbohydrate Nanomedicines: Potential Utility of Gold Nanoparticle Models as a Roadmap.

Authors: Alston, Amy Barton Lin, Zhoumeng Gustafson, Heather Herd et al.

Source: Clinical Pharmacokinetics. Oct2025, Vol. 64 Issue 10, p1477-1494. 18p.

Physicochemical characterization of ferric carboxymaltose and iron sucrose nanoparticles in human plasma: stability and nanoparticle-protein complex formation.

Authors: Soliman, Mahmoud G. Santana-Otero, Antonio Digigow, Reinaldo et al.

Source: Journal of Colloid & Interface Science. Dec2026, Vol. 723, pN.PAG-N.PAG. 1p.

Subjects: Colloidal stability, Nanoparticles, Blood plasma, Blood proteins, Colloid analysis

Nanoparticle‐mediated targeting of autoantigen peptide to cross‐presenting liver sinusoidal endothelial cells protects from CD8 T‐cell‐driven autoimmune cholangitis.

Authors: Carambia, Antonella Gottwick, Cornelia Schwinge, Dorothee et al.

Source: Immunology. Apr2021, Vol. 162 Issue 4, p452-463. 12p.

Iron-carbohydrate complexes treating iron anaemia: Understanding the nano-structure and interactions with proteins through orthogonal characterisation.

Authors: Krupnik, Leonard Avaro, Jonathan Liebi, Marianne et al.

Source: Journal of Controlled Release. Apr2024, Vol. 368, p566-579. 14p.

Comparing iron sucrose and ferric carboxymaltose interactions with murine and human macrophages: Focus on the lysosomal compartment.

Authors: Sousa de Almeida, Mauro Bazzoni, Amélie Balog, Sandor et al.

Source: European Journal of Pharmaceutical Sciences. Feb2026, Vol. 217, pN.PAG-N.PAG. 1p.

Understanding the kinetics of macrophage uptake and the metabolic fate of iron-carbohydrate complexes used for iron deficiency anemia treatment.

Authors: Eitner, Stephanie Kissling, Vera M. Rippl, Alexandra et al.

Source: Journal of Controlled Release. Nov2025, Vol. 387, pN.PAG-N.PAG. 1p.

Go with the flow: An in vitro model of a mature endothelium for the study of the bioresponse of IV injectable nanomedicines.

Authors: Nikravesh, Niusha Rippl, Alexandra Hoch, Tobias et al.

Source: Toxicology in Vitro. Dec2024, Vol. 101, pN.PAG-N.PAG. 1p.

Amino covalent binding approach on iron oxide nanoparticle surface: Toward biological applications

Authors: Griffete, Nébéwia Clift, Martin J.D. Lamouri, Aazdine et al.

Source: Colloids & Surfaces A: Physicochemical & Engineering Aspects. Dec2012, Vol. 415, p98-104. 7p.

Uncovering the dynamics of cellular responses induced by iron-carbohydrate complexes in human macrophages using quantitative proteomics and phosphoproteomics.

Authors: Bossart, Jonas Rippl, Alexandra Barton Alston, Amy E. et al.

Source: Biomedicine & Pharmacotherapy. Oct2023, Vol. 166, pN.PAG-N.PAG. 1p.

Critical nanomaterial attributes of iron-carbohydrate nanoparticles: Leveraging orthogonal methods to resolve the 3-dimensional structure.

Authors: Krupnik, Leonard Joshi, Prachi Kappler, Andreas et al.

Source: European Journal of Pharmaceutical Sciences. Sep2023, Vol. 188, pN.PAG-N.PAG. 1p.

Nanoparticles targeting liver sinusoidal endothelial cells improve tolerance to vector and transgene antigens through tolerance spreading.

Authors: Hardet R Wang SH Delignat S et al.

Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 Jul 01; Vol. 34 (7), pp. 3854-3871. Date of Electronic Publication: 2026 Mar 12.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

Nanoparticle platform preferentially targeting liver sinusoidal endothelial cells induces tolerance in CD4+ T cell-mediated disease models.

Authors: Wang SH Serr I Digigow R et al.

Source: Frontiers in immunology [Front Immunol] 2025 Mar 17; Vol. 16, pp. 1542380. Date of Electronic Publication: 2025 Mar 17 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE

Safety, tolerability, pharmacokinetics and pharmacodynamic effects of desmoglein 3 peptide-coupled tolerizing nanoparticles in pemphigus.

Authors: Didona D Hudemann C Garn H et al.

Source: The British journal of dermatology [Br J Dermatol] 2026 Jan 06; Vol. 194 (1), pp. 86-98.

Publication Type: Journal Article; Clinical Trial, Phase I

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0004041 Publication Model: Print Cited Medium: Internet ISSN: 1365-2133 (Electronic) Linking ISSN: 00070963 NLM ISO Abbreviation: Br J Dermatol Subsets: MEDLINE

Tracking Intracellular Labile Iron with a Genetically Encoded Fluorescent Reporter System Based on Protein Stability.

Authors: Akyol A Çimen Ş Gottschalk B et al.

Source: ACS sensors [ACS Sens] 2025 Aug 22; Vol. 10 (8), pp. 5854-5861. Date of Electronic Publication: 2025 Aug 01.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101669031 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-3694 (Electronic) Linking ISSN: 23793694 NLM ISO Abbreviation: ACS Sens Subsets: MEDLINE

Nano-scale characterization of iron-carbohydrate complexes by cryogenic scanning transmission electron microscopy: Building the bridge to biorelevant characterization.

Authors: Digigow R Burgert M Luechinger M et al.

Source: Heliyon [Heliyon] 2024 Aug 24; Vol. 10 (17), pp. e36749. Date of Electronic Publication: 2024 Aug 24 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101672560 Publication Model: eCollection Cited Medium: Print ISSN: 2405-8440 (Print) Linking ISSN: 24058440 NLM ISO Abbreviation: Heliyon Subsets: PubMed not MEDLINE