Search Results - "Durrant CS"

Emerging directions in tauopathy research.

Authors: Buée L Wildsmith KR Alladi S et al.

Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Jun; Vol. 22 (6), pp. e71431.

Publication Type: Journal Article; Review

Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE

GABAB Receptor signaling in CA1 Pyramidal Cells is not Regulated by Aging in the APP/PS1 Mouse Model of Amyloid Pathology.

Authors: Meftah S Wilson MA Elliott J et al.

Source: ENeuro [eNeuro] 2026 Feb 06; Vol. 13 (2). Date of Electronic Publication: 2026 Feb 06 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 101647362 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2822 (Electronic) Linking ISSN: 23732822 NLM ISO Abbreviation: eNeuro Subsets: MEDLINE

A timeline of tau-mediated synaptotoxicity.

Authors: Bonthron CK Durrant CS

Source: Trends in neurosciences [Trends Neurosci] 2026 May; Vol. 49 (5), pp. 321-323. Date of Electronic Publication: 2026 Apr 11.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Applied Science Publishing Country of Publication: England NLM ID: 7808616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-108X (Electronic) Linking ISSN: 01662236 NLM ISO Abbreviation: Trends Neurosci Subsets: MEDLINE

Confirmation of p-tau Ser356's association with Alzheimer's disease pathology and lowering in response to WZ4003 treatment in brain slice cultures. Reply to: "Phospho-tau Ser356 is mostly confined to pre-NFT neurons in Alzheimer's pathology".

Authors: Taylor LW Simzer EM Young LFP et al.

Source: Acta neuropathologica [Acta Neuropathol] 2025 Dec 11; Vol. 150 (1), pp. 63. Date of Electronic Publication: 2025 Dec 11.

Publication Type: Letter

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE; In Process

Drosophila appear resistant to trans-synaptic tau propagation.

Authors: Catterson JH Mouofo EN López De Toledo Soler I et al.

Source: Brain communications [Brain Commun] 2024 Aug 08; Vol. 6 (4), pp. fcae256. Date of Electronic Publication: 2024 Aug 08 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE

A nose for tau.

Authors: Meftah S Durrant CS Spires-Jones TL

Source: Science translational medicine [Sci Transl Med] 2024 Jul 03; Vol. 16 (754), pp. eadq6489. Date of Electronic Publication: 2024 Jul 03.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Evidence for trans-synaptic propagation of oligomeric tau in human progressive supranuclear palsy.

Authors: McGeachan RI Keavey L Simzer EM et al.

Source: Nature neuroscience [Nat Neurosci] 2025 Aug; Vol. 28 (8), pp. 1622-1634. Date of Electronic Publication: 2025 Jul 16.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE

Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease.

Authors: Colom-Cadena M Toombs J Simzer E et al.

Source: Acta neuropathologica [Acta Neuropathol] 2024 Feb 06; Vol. 147 (1), pp. 32. Date of Electronic Publication: 2024 Feb 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

p-tau Ser356 is associated with Alzheimer's disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003.

Authors: Taylor LW Simzer EM Pimblett C et al.

Source: Acta neuropathologica [Acta Neuropathol] 2024 Jan 04; Vol. 147 (1), pp. 7. Date of Electronic Publication: 2024 Jan 04.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

Phylogenetic divergence of GABAB receptor signaling in neocortical networks over adult life.

Authors: Wilson MA Sumera A Taylor LW et al.

Source: Nature communications [Nat Commun] 2025 May 06; Vol. 16 (1), pp. 4194. Date of Electronic Publication: 2025 May 06.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Divergent actions of physiological and pathological amyloid-β on synapses in live human brain slice cultures.

Authors: McGeachan RI Meftah S Taylor LW et al.

Source: Nature communications [Nat Commun] 2025 Apr 30; Vol. 16 (1), pp. 3753. Date of Electronic Publication: 2025 Apr 30.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Alzheimer's disease-like neuropathology in three species of oceanic dolphin.

Authors: Vacher MC Durrant CS Rose J et al.

Source: The European journal of neuroscience [Eur J Neurosci] 2023 Apr; Vol. 57 (7), pp. 1161-1179. Date of Electronic Publication: 2022 Dec 27.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: France NLM ID: 8918110 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-9568 (Electronic) Linking ISSN: 0953816X NLM ISO Abbreviation: Eur J Neurosci Subsets: MEDLINE

Is amyloid-β a friend or foe?

Authors: Durrant CS; Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK. claire.durrant@ed.ac.uk.; UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK. claire.durrant@ed.ac.uk.

Source: Nature reviews. Molecular cell biology [Nat Rev Mol Cell Biol] 2024 Jul; Vol. 25 (7), pp. 516.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100962782 Publication Model: Print Cited Medium: Internet ISSN: 1471-0080 (Electronic) Linking ISSN: 14710072 NLM ISO Abbreviation: Nat Rev Mol Cell Biol Subsets: MEDLINE

The physiological roles of tau and Aβ: implications for Alzheimer's disease pathology and therapeutics.

Authors: Kent SA Spires-Jones TL Durrant CS

Source: Acta neuropathologica [Acta Neuropathol] 2020 Oct; Vol. 140 (4), pp. 417-447. Date of Electronic Publication: 2020 Jul 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

Protein retention in the endoplasmic reticulum rescues Aβ toxicity in Drosophila.

Authors: Catterson JH Minkley L Aspe S et al.

Source: Neurobiology of aging [Neurobiol Aging] 2023 Dec; Vol. 132, pp. 154-174. Date of Electronic Publication: 2023 Sep 21.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8100437 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-1497 (Electronic) Linking ISSN: 01974580 NLM ISO Abbreviation: Neurobiol Aging Subsets: MEDLINE

Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling.

Authors: Durrant CS Ruscher K Sheppard O et al.

Source: Cell death & disease [Cell Death Dis] 2020 Feb 06; Vol. 11 (2), pp. 98. Date of Electronic Publication: 2020 Feb 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

Synaptic degeneration in Alzheimer disease.

Authors: Tzioras M McGeachan RI Durrant CS et al.

Source: Nature reviews. Neurology [Nat Rev Neurol] 2023 Jan; Vol. 19 (1), pp. 19-38. Date of Electronic Publication: 2022 Dec 13.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500072 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-4766 (Electronic) Linking ISSN: 17594758 NLM ISO Abbreviation: Nat Rev Neurol Subsets: MEDLINE

Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue.

Authors: Miller LVC Mukadam AS Durrant CS et al.

Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2021 Mar 12; Vol. 9 (1), pp. 41. Date of Electronic Publication: 2021 Mar 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE

Preparation of Organotypic Hippocampal Slice Cultures for the Study of CNS Disease and Damage.

Authors: Durrant CS; Centre for Discovery Brain Sciences, The University of Edinburgh, Edinburgh, Scotland, UK. claire.durrant@ed.ac.uk.

Source: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2020; Vol. 2143, pp. 133-144.

Publication Type: Journal Article

Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

Lipopolysaccharide-induced neuroinflammation induces presynaptic disruption through a direct action on brain tissue involving microglia-derived interleukin 1 beta.

Authors: Sheppard O Coleman MP Durrant CS

Source: Journal of neuroinflammation [J Neuroinflammation] 2019 May 18; Vol. 16 (1), pp. 106. Date of Electronic Publication: 2019 May 18.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE