Search Results - "Eadsforth TC"

Residue-Level Determination of Small-Molecule-Protein Affinities by Hydrogen-Deuterium Exchange Mass Spectrometry.

Authors: Lin Magalhaes LG McMillan J et al.

Source: Journal of the American Society for Mass Spectrometry [J Am Soc Mass Spectrom] 2026 Jun 03; Vol. 37 (6), pp. 1391-1401. Date of Electronic Publication: 2026 Mar 31.

Publication Type: Journal Article

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 9010412 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1123 (Electronic) Linking ISSN: 10440305 NLM ISO Abbreviation: J Am Soc Mass Spectrom Subsets: MEDLINE

Biophysical analysis of an oligomerization-attenuated variant of the Leishmania donovani dynamin-1-like protein.

Authors: Wuyts E Sundaramoorthy R Tulloch L et al.

Source: Molecular and biochemical parasitology [Mol Biochem Parasitol] 2025 Sep; Vol. 263, pp. 111691. Date of Electronic Publication: 2025 Aug 14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8006324 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9428 (Electronic) Linking ISSN: 01666851 NLM ISO Abbreviation: Mol Biochem Parasitol Subsets: MEDLINE

Pharmacological and structural understanding of the Trypanosoma cruzi proteasome provides key insights for developing site-specific inhibitors.

Authors: Eadsforth TC Torrie LS Rowland P et al.

Source: The Journal of biological chemistry [J Biol Chem] 2025 Jan; Vol. 301 (1), pp. 108049. Date of Electronic Publication: 2024 Dec 09.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.

Authors: Green SR Wilson C Eadsforth TC et al.

Source: Journal of medicinal chemistry [J Med Chem] 2023 Nov 23; Vol. 66 (22), pp. 15380-15408. Date of Electronic Publication: 2023 Nov 10.

Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening.

Authors: Prakash O Führing J Post J et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2019 Mar 12; Vol. 24 (5). Date of Electronic Publication: 2019 Mar 12.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Structure of the SCAN domain of human paternally expressed gene 3 protein.

Authors: Rimsa V Eadsforth TC Hunter WN

Source: PloS one [PLoS One] 2013 Jul 23; Vol. 8 (7), pp. e69538. Date of Electronic Publication: 2013 Jul 23 (Print Publication: 2013).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Acinetobacter baumannii FolD ligand complexes --potent inhibitors of folate metabolism and a re-evaluation of the structure of LY374571.

Authors: Eadsforth TC Maluf FV Hunter WN

Source: The FEBS journal [FEBS J] 2012 Dec; Vol. 279 (23), pp. 4350-60. Date of Electronic Publication: 2012 Nov 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

Assessment of Pseudomonas aeruginosa N5,N10-methylenetetrahydrofolate dehydrogenase-cyclohydrolase as a potential antibacterial drug target.

Authors: Eadsforth TC Gardiner M Maluf FV et al.

Source: PloS one [PLoS One] 2012; Vol. 7 (4), pp. e35973. Date of Electronic Publication: 2012 Apr 25.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Crystal structures of Burkholderia cenocepacia dihydropteroate synthase in the apo-form and complexed with the product 7,8-dihydropteroate.

Authors: Morgan RE Batot GO Dement JM et al.

Source: BMC structural biology [BMC Struct Biol] 2011 May 09; Vol. 11, pp. 21. Date of Electronic Publication: 2011 May 09.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101088689 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6807 (Electronic) Linking ISSN: 14726807 NLM ISO Abbreviation: BMC Struct Biol Subsets: MEDLINE

Pseudomonas aeruginosa 4-amino-4-deoxychorismate lyase: spatial conservation of an active site tyrosine and classification of two types of enzyme.

Authors: O'Rourke PE Eadsforth TC Fyfe PK et al.

Source: PloS one [PLoS One] 2011; Vol. 6 (9), pp. e24158. Date of Electronic Publication: 2011 Sep 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide.

Authors: Bisson C Britton KL Sedelnikova SE et al.

Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2016 Oct 17; Vol. 55 (43), pp. 13485-13489. Date of Electronic Publication: 2016 Sep 26.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3773 (Electronic) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: PubMed not MEDLINE

Characterization of 2,4-Diamino-6-oxo-1,6-dihydropyrimidin-5-yl Ureido Based Inhibitors of Trypanosoma brucei FolD and Testing for Antiparasitic Activity.

Authors: Eadsforth TC Pinto A Luciani R et al.

Source: Journal of medicinal chemistry [J Med Chem] 2015 Oct 22; Vol. 58 (20), pp. 7938-48. Date of Electronic Publication: 2015 Sep 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.

Authors: Bisson C Britton KL Sedelnikova SE et al.

Source: Structure (London, England : 1993) [Structure] 2015 Jul 07; Vol. 23 (7), pp. 1236-45. Date of Electronic Publication: 2015 Jun 18.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE

High-resolution structure of the M14-type cytosolic carboxypeptidase from Burkholderia cenocepacia refined exploiting PDB_REDO strategies.

Authors: Rimsa V Eadsforth TC Joosten RP et al.

Source: Acta crystallographica. Section D, Biological crystallography [Acta Crystallogr D Biol Crystallogr] 2014 Feb; Vol. 70 (Pt 2), pp. 279-89. Date of Electronic Publication: 2014 Jan 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 9305878 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-0047 (Electronic) Linking ISSN: 09074449 NLM ISO Abbreviation: Acta Crystallogr D Biol Crystallogr Subsets: MEDLINE

Two high-resolution structures of the human E3 ubiquitin ligase Siah1.

Authors: Rimsa V Eadsforth TC Hunter WN

Source: Acta crystallographica. Section F, Structural biology and crystallization communications [Acta Crystallogr Sect F Struct Biol Cryst Commun] 2013 Dec; Vol. 69 (Pt 12), pp. 1339-43. Date of Electronic Publication: 2013 Nov 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101226117 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-3091 (Electronic) Linking ISSN: 17443091 NLM ISO Abbreviation: Acta Crystallogr Sect F Struct Biol Cryst Commun Subsets: MEDLINE

The crystal structure of Leishmania major N(5),N(10)-methylenetetrahydrofolate dehydrogenase/cyclohydrolase and assessment of a potential drug target.

Authors: Eadsforth TC Cameron S Hunter WN

Source: Molecular and biochemical parasitology [Mol Biochem Parasitol] 2012 Feb; Vol. 181 (2), pp. 178-85. Date of Electronic Publication: 2011 Nov 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8006324 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9428 (Electronic) Linking ISSN: 01666851 NLM ISO Abbreviation: Mol Biochem Parasitol Subsets: MEDLINE

Structure and mechanism of imidazoleglycerol-phosphate dehydratase.

Authors: Glynn SE Baker PJ Sedelnikova SE et al.

Source: Structure (London, England : 1993) [Structure] 2005 Dec; Vol. 13 (12), pp. 1809-17.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print Cited Medium: Print ISSN: 0969-2126 (Print) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE