Search Results - "Edbauer D"

Theme 06 - Tissue Biomarkers.

Authors: Bobeva, Y. Castro-Gomez, S. Kittipeerapat, N. et al.

Source: Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. Nov2022 Suppl 1, Vol. 23 Issue 1, p99-109. 11p.

Genetic modifications of the adeno-associated virus type 2 capsid reduce the affinity and the neutralizing effects of human serum antibodies.

Authors: Huttner, N. A. Girod, A. Perabo, L. et al.

Source: Gene Therapy. Dec2003, Vol. 10 Issue 26, p2139-2147. 9p.

Pathomechanismen und klinische Aspekte der frontotemporalen Lobärdegeneration.

Alternate Title: Pathomechanisms and clinical aspects of frontotemporal lobar degeneration.

Authors: Bürger, K. Arzberger, T. Stephan, J. et al.

Source: Der Nervenarzt. Feb2017, Vol. 88 Issue 2, p163-172. 10p.

Direct interaction between TDP-43 and Tau promotes their co-condensation, while suppressing Tau fibril formation and seeding.

Authors: Simonetti F Zhong W Hutten S et al.

Source: The EMBO journal [EMBO J] 2025 Dec; Vol. 44 (24), pp. 7395-7433. Date of Electronic Publication: 2025 Oct 17.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

Homozygosity for the C allele at UNC13A rs12608932 seems to compromise cognition in ALS independently of the cognitive domains.

Authors: Lehto A Zapf A Hermann A et al.

Source: Amyotrophic lateral sclerosis & frontotemporal degeneration [Amyotroph Lateral Scler Frontotemporal Degener] 2026 May; Vol. 27 (3-4), pp. 348-351. Date of Electronic Publication: 2026 Jan 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 101587185 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2167-9223 (Electronic) Linking ISSN: 21678421 NLM ISO Abbreviation: Amyotroph Lateral Scler Frontotemporal Degener Subsets: MEDLINE

Constitutive neuronal expression and disease-associated upregulation of chitinases in amyotrophic lateral sclerosis.

Authors: Gaur N Angerer C Gunes ZI et al.

Source: Brain : a journal of neurology [Brain] 2026 Feb 28. Date of Electronic Publication: 2026 Feb 28.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE

Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing.

Authors: Pottier C Küçükali F Baker M et al.

Source: Nature communications [Nat Commun] 2025 Apr 25; Vol. 16 (1), pp. 3914. Date of Electronic Publication: 2025 Apr 25.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Correction to: Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins.

Authors: Mori K Arzberger T Grässer FA et al.

Source: Acta neuropathologica [Acta Neuropathol] 2024 Oct 05; Vol. 148 (1), pp. 48. Date of Electronic Publication: 2024 Oct 05.

Publication Type: Published Erratum

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE; PubMed not MEDLINE

Poly-GP accumulation due to C9orf72 loss of function induces motor neuron apoptosis through autophagy and mitophagy defects.

Authors: de Calbiac H Renault S Haouy G et al.

Source: Autophagy [Autophagy] 2024 Oct; Vol. 20 (10), pp. 2164-2185. Date of Electronic Publication: 2024 Sep 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101265188 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8635 (Electronic) Linking ISSN: 15548627 NLM ISO Abbreviation: Autophagy Subsets: MEDLINE

Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.

Authors: Riemenschneider H Guo Q Bader J et al.

Source: EMBO reports [EMBO Rep] 2024 Jul; Vol. 25 (7), pp. 3161.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE; PubMed not MEDLINE

Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target.

Authors: Caldi Gomes L Hänzelmann S Hausmann F et al.

Source: Nature communications [Nat Commun] 2024 Jun 07; Vol. 15 (1), pp. 4893. Date of Electronic Publication: 2024 Jun 07.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration.

Authors: Reich M Simon MJ Polke B et al.

Source: Science translational medicine [Sci Transl Med] 2024 Jun 05; Vol. 16 (750), pp. eadj7308. Date of Electronic Publication: 2024 Jun 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Comparative CRISPRi screens reveal a human stem cell dependence on mRNA translation-coupled quality control.

Authors: Rodschinka G Forcelloni S Kühner FM et al.

Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Oct; Vol. 32 (10), pp. 1932-1946. Date of Electronic Publication: 2025 Jul 11.

Publication Type: Journal Article; Comparative Study

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

Authors: Jülg J Edbauer D Behrends C

Source: EMBO reports [EMBO Rep] 2023 Aug 03; Vol. 24 (8), pp. e55895. Date of Electronic Publication: 2023 Jun 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mice.

Authors: Rezaei A Kocsis-Jutka V Gunes ZI et al.

Source: Nature communications [Nat Commun] 2025 Apr 11; Vol. 16 (1), pp. 3442. Date of Electronic Publication: 2025 Apr 11.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

A perturbed network in neurodegeneration.

Authors: Gallo JM Edbauer D

Source: Science (New York, N.Y.) [Science] 2022 Oct 07; Vol. 378 (6615), pp. 28-29. Date of Electronic Publication: 2022 Oct 06.

Publication Type: Journal Article; Comment

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD-associated UBQLN2 mutants.

Authors: Strohm L Hu Z Suk Y et al.

Source: Life science alliance [Life Sci Alliance] 2022 Jul 01; Vol. 5 (11). Date of Electronic Publication: 2022 Jul 01 (Print Publication: 2022).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE

Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.

Authors: Riemenschneider H Guo Q Bader J et al.

Source: EMBO reports [EMBO Rep] 2022 Jun 07; Vol. 23 (6), pp. e53890. Date of Electronic Publication: 2022 Apr 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.

Authors: Gruijs da Silva LA Simonetti F Hutten S et al.

Source: The EMBO journal [EMBO J] 2022 Apr 19; Vol. 41 (8), pp. e108443. Date of Electronic Publication: 2022 Feb 03.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

Author Correction: Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.

Authors: Parhizkar S Arzberger T Brendel M et al.

Source: Nature neuroscience [Nat Neurosci] 2024 Sep; Vol. 27 (9), pp. 1858-1859.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE; PubMed not MEDLINE