Search Results - "Edge ASB"

Sox2 interacts with Atoh1 and Huwe1 loci to regulate Atoh1 transcription and stability during hair cell differentiation.

Authors: Cheng YF Kempfle JS Chiang H et al.

Source: PLoS genetics [PLoS Genet] 2025 Jan 30; Vol. 21 (1), pp. e1011573. Date of Electronic Publication: 2025 Jan 30 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

Cellular Reprogramming by Notch Inhibition Regenerates Hair Cells and Afferent Neurons to Restore the Sense of Balance.

Authors: Lahlou H Zhu H Zhou W et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Sep 26. Date of Electronic Publication: 2025 Sep 26.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Large-scale annotated dataset for cochlear hair cell detection and classification.

Authors: Buswinka CJ Rosenberg DB Simikyan RG et al.

Source: Scientific data [Sci Data] 2024 Apr 23; Vol. 11 (1), pp. 416. Date of Electronic Publication: 2024 Apr 23.

Publication Type: Dataset; Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101640192 Publication Model: Electronic Cited Medium: Internet ISSN: 2052-4463 (Electronic) Linking ISSN: 20524463 NLM ISO Abbreviation: Sci Data Subsets: MEDLINE

A phase I/IIa safety and efficacy trial of intratympanic gamma-secretase inhibitor as a regenerative drug treatment for sensorineural hearing loss.

Authors: Schilder AGM Wolpert S Saeed S et al.

Corporate Authors: Schilder AGM Wolpert S Saeed S et al.

Source: Nature communications [Nat Commun] 2024 Mar 01; Vol. 15 (1), pp. 1896. Date of Electronic Publication: 2024 Mar 01.

Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Auditory hair cells and spiral ganglion neurons regenerate synapses with refined release properties in vitro.

Authors: Vincent PFY Young ED Edge ASB et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jul 30; Vol. 121 (31), pp. e2315599121. Date of Electronic Publication: 2024 Jul 26.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Altered expression of genes regulating inflammation and synaptogenesis during regrowth of afferent neurons to cochlear hair cells.

Authors: Wu CC Brugeaud A Seist R et al.

Source: PloS one [PLoS One] 2020 Oct 01; Vol. 15 (10), pp. e0238578. Date of Electronic Publication: 2020 Oct 01 (Print Publication: 2020).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Auditory Hair Cells and Spiral Ganglion Neurons Regenerate Synapses with Refined Release Properties In Vitro.

Authors: Vincent PFY Young ED Edge ASB et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Dec 02. Date of Electronic Publication: 2023 Dec 02.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Cochlear organoids reveal transcriptional programs of postnatal hair cell differentiation from supporting cells.

Authors: Kalra G Lenz D Abdul-Aziz D et al.

Source: Cell reports [Cell Rep] 2023 Nov 28; Vol. 42 (11), pp. 113421. Date of Electronic Publication: 2023 Nov 11.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

Regeneration of Cochlear Synapses by Systemic Administration of a Bisphosphonate.

Authors: Seist R Tong M Landegger LD et al.

Source: Frontiers in molecular neuroscience [Front Mol Neurosci] 2020 Jul 14; Vol. 13, pp. 87. Date of Electronic Publication: 2020 Jul 14 (Print Publication: 2020).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477914 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5099 (Print) Linking ISSN: 16625099 NLM ISO Abbreviation: Front Mol Neurosci Subsets: PubMed not MEDLINE

Lin28 reprograms inner ear glia to a neuronal fate.

Authors: Kempfle JS Luu NC Petrillo M et al.

Source: Stem cells (Dayton, Ohio) [Stem Cells] 2020 Jul; Vol. 38 (7), pp. 890-903. Date of Electronic Publication: 2020 Apr 30.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 9304532 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-4918 (Electronic) Linking ISSN: 10665099 NLM ISO Abbreviation: Stem Cells Subsets: MEDLINE

Increasing the expression level of ChR2 enhances the optogenetic excitability of cochlear neurons.

Authors: Meng X Murali S Cheng YF et al.

Source: Journal of neurophysiology [J Neurophysiol] 2019 Nov 01; Vol. 122 (5), pp. 1962-1974. Date of Electronic Publication: 2019 Sep 18.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0375404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1598 (Electronic) Linking ISSN: 00223077 NLM ISO Abbreviation: J Neurophysiol Subsets: MEDLINE

ERBB2 signaling drives supporting cell proliferation in vitro and apparent supernumerary hair cell formation in vivo in the neonatal mouse cochlea.

Authors: Zhang J Wang Q Abdul-Aziz D et al.

Source: The European journal of neuroscience [Eur J Neurosci] 2018 Nov; Vol. 48 (10), pp. 3299-3316. Date of Electronic Publication: 2018 Oct 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Wiley-Blackwell Country of Publication: France NLM ID: 8918110 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-9568 (Electronic) Linking ISSN: 0953816X NLM ISO Abbreviation: Eur J Neurosci Subsets: MEDLINE

In vivo base editing of post-mitotic sensory cells.

Authors: Yeh WH Chiang H Rees HA et al.

Source: Nature communications [Nat Commun] 2018 Jun 05; Vol. 9 (1), pp. 2184. Date of Electronic Publication: 2018 Jun 05.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Norrie disease protein is essential for cochlear hair cell maturation.

Authors: Hayashi Y Chiang H Tian C et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Sep 28; Vol. 118 (39).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery.

Authors: Rees HA Komor AC Yeh WH et al.

Source: Nature communications [Nat Commun] 2017 Jun 06; Vol. 8, pp. 15790. Date of Electronic Publication: 2017 Jun 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Hair Cell Generation in Cochlear Culture Models Mediated by Novel γ-Secretase Inhibitors.

Authors: Erni ST Gill JC Palaferri C et al.

Source: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2021 Aug 13; Vol. 9, pp. 710159. Date of Electronic Publication: 2021 Aug 13 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE

HIC1 Represses Atoh1 Transcription and Hair Cell Differentiation in the Cochlea.

Authors: Abdul-Aziz D Hathiramani N Phung L et al.

Source: Stem cell reports [Stem Cell Reports] 2021 Apr 13; Vol. 16 (4), pp. 797-809. Date of Electronic Publication: 2021 Mar 25.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

An antibody to RGMa promotes regeneration of cochlear synapses after noise exposure.

Authors: Nevoux J Alexandru M Bellocq T et al.

Source: Scientific reports [Sci Rep] 2021 Feb 03; Vol. 11 (1), pp. 2937. Date of Electronic Publication: 2021 Feb 03.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

Increased Type I and Decreased Type II Hair Cells after Deletion of Sox2 in the Developing Mouse Utricle.

Authors: Lu J Hu L Ye B et al.

Source: Neuroscience [Neuroscience] 2019 Dec 01; Vol. 422, pp. 146-160. Date of Electronic Publication: 2019 Oct 31.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

Inner ear organoids: new tools to understand neurosensory cell development, degeneration and regeneration.

Authors: Roccio M Edge ASB

Source: Development (Cambridge, England) [Development] 2019 Sep 02; Vol. 146 (17). Date of Electronic Publication: 2019 Sep 02.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE