Search Results - "El Botty R"

Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA-mutated metaplastic breast cancers.

Authors: Coussy, F. El Botty, R. Lavigne, M. et al.

Source: Journal of Hematology & Oncology. 2/22/2020, Vol. 13 Issue 1, p1-10. 10p.

400 - The MEK1/2 inhibitor selumetinib (AZD6244; ARRY-142886) appears as an efficient targeted therapy when used in an adjuvant setting in patient-derived xenografts of uveal melanoma.

Authors: Diallo, B. Massonnet, G. El-Botty, R. et al.

Source: European Journal of Cancer. Dec2016 Supplement 1, Vol. 69, pS132-S132. 1p.

Clinical value of R-spondins in triple-negative and metaplastic breast cancers.

Authors: Coussy, F Lallemand, F Vacher, S et al.

Source: British Journal of Cancer. 6/6/2017, Vol. 116 Issue 12, p1595-1603. 9p. 1 Diagram, 2 Charts, 3 Graphs.

Targeting PRMTs Creates Vulnerability of DNA Double-Stand Break Repair Pathways, and Potentiates Chemotherapy Efficacy in TNBC.

Authors: Thiebaut C Martinez S Pruvost L et al.

Source: Cancer science [Cancer Sci] 2026 May; Vol. 117 (5), pp. 1273-1285. Date of Electronic Publication: 2026 Mar 09.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE

Homologous recombination deficiency and hemizygosity drive resistance in breast cancer.

Authors: Safonov A Lee M Brown DN et al.

Source: Nature [Nature] 2026 Apr; Vol. 652 (8110), pp. 752-762. Date of Electronic Publication: 2026 Mar 04.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

ESR1-Activating Mutations Confer Metabolic Vulnerabilities in ER+ Breast Cancer.

Authors: Bonechi F Bacci M Lorito N et al.

Source: Cancer research [Cancer Res] 2026 Feb 02; Vol. 86 (3), pp. 679-692.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Acetyl-CoA carboxylase 1 controls a lipid droplet-peroxisome axis and is a vulnerability of endocrine-resistant ER⁺ breast cancer.

Authors: Bacci M Lorito N Smiriglia A et al.

Source: Science translational medicine [Sci Transl Med] 2024 Feb 28; Vol. 16 (736), pp. eadf9874. Date of Electronic Publication: 2024 Feb 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers.

Authors: Haykal MM Rodrigues-Ferreira S El Botty R et al.

Source: Cancer letters [Cancer Lett] 2025 Jun 28; Vol. 620, pp. 217665. Date of Electronic Publication: 2025 Mar 22.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

HORMAD1 overexpression predicts response to anthracycline-cyclophosphamide and survival in triple-negative breast cancers.

Authors: El-Botty R Vacher S Mainguené J et al.

Source: Molecular oncology [Mol Oncol] 2023 Oct; Vol. 17 (10), pp. 2017-2028. Date of Electronic Publication: 2023 Mar 23.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE

Oxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers.

Authors: El-Botty R Morriset L Montaudon E et al.

Source: Nature communications [Nat Commun] 2023 Jul 14; Vol. 14 (1), pp. 4221. Date of Electronic Publication: 2023 Jul 14.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors.

Authors: Musiani D Yücel H Vallette M et al.

Source: Molecular cell [Mol Cell] 2025 Mar 20; Vol. 85 (6), pp. 1072-1084.e10. Date of Electronic Publication: 2025 Feb 25.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

Acetalax and Bisacodyl for the Treatment of Triple-Negative Breast Cancer: A Combined Molecular and Preclinical Study.

Authors: Reinhold WC Marangoni E Elloumi F et al.

Source: Cancer research communications [Cancer Res Commun] 2025 Feb 01; Vol. 5 (2), pp. 375-388.

Publication Type: Journal Article

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE

Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers.

Authors: Ter Brugge P Moser SC Bièche I et al.

Source: Nature communications [Nat Commun] 2023 Apr 07; Vol. 14 (1), pp. 1958. Date of Electronic Publication: 2023 Apr 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Evaluation of Combined Chemotherapy and Genomic-Driven Targeted Therapy in Patient-Derived Xenografts Identifies New Therapeutic Approaches in Squamous Non-Small-Cell Lung Cancer Patients.

Authors: Decaudin D Némati F Masliah Planchon J et al.

Source: Cancers [Cancers (Basel)] 2024 Aug 07; Vol. 16 (16). Date of Electronic Publication: 2024 Aug 07.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE

HRAS is a therapeutic target in malignant chemo-resistant adenomyoepithelioma of the breast.

Authors: Bièche I Coussy F El-Botty R et al.

Source: Journal of hematology & oncology [J Hematol Oncol] 2021 Sep 08; Vol. 14 (1), pp. 143. Date of Electronic Publication: 2021 Sep 08.

Publication Type: Letter; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722 (Electronic) Linking ISSN: 17568722 NLM ISO Abbreviation: J Hematol Oncol Subsets: MEDLINE

PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance.

Authors: Montaudon E Nikitorowicz-Buniak J Sourd L et al.

Source: Nature communications [Nat Commun] 2020 Aug 13; Vol. 11 (1), pp. 4053. Date of Electronic Publication: 2020 Aug 13.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Targeting Transcriptional Regulation with a CDK9 Inhibitor Suppresses Growth of Endocrine- and Palbociclib-Resistant ER+ Breast Cancers.

Authors: Soosainathan A Iravani M El-Botty R et al.

Source: Cancer research [Cancer Res] 2024 Jan 02; Vol. 84 (1), pp. 17-25.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers.

Authors: Coussy F El-Botty R Château-Joubert S et al.

Source: Science translational medicine [Sci Transl Med] 2020 Feb 19; Vol. 12 (531).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

Interaction between IGF2-PI3K axis and cancer-associated-fibroblasts promotes anal squamous carcinogenesis.

Authors: Cacheux W Lièvre A Richon S et al.

Source: International journal of cancer [Int J Cancer] 2019 Oct 01; Vol. 145 (7), pp. 1852-1859. Date of Electronic Publication: 2019 Feb 18.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE

A large collection of integrated genomically characterized patient-derived xenografts highlighting the heterogeneity of triple-negative breast cancer.

Authors: Coussy F de Koning L Lavigne M et al.

Source: International journal of cancer [Int J Cancer] 2019 Oct 01; Vol. 145 (7), pp. 1902-1912. Date of Electronic Publication: 2019 Apr 04.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE