Search Results - "Epistasis (Genetics)"

Rapid directed evolution guided by protein language models and epistatic interactions.

Authors: Tran, Vincent Q. Nemeth, Matthew Bartie, Liam J. et al.

Source: Science. 5/7/2026, Vol. 392 Issue 6798, p1-13. 13p.

Deep mutational scanning of recent SARS-CoV-2 variants highlights changing amino acid preferences within epistatic hotspot residues.

Authors: Taylor, Ashley L. Starr, Tyler N.

Source: PLoS Pathogens. 6/22/2026, Vol. 22 Issue 6, p1-19. 19p.

Epistasis among clustered lineage-specific amino acid substitutions in the Drosophila Trio protein.

Authors: Borne, Flora Taverner, Andrew M. Andolfatto, Peter

Source: PLoS Genetics. 6/3/2026, Vol. 22 Issue 6, p1-19. 19p.

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Energetic frustration dictates cognate specificity of two-component signaling system.

Authors: Li, Yuqing Li, Peng Nie, Junhui et al.

Source: Communications Physics. 5/5/2026, Vol. 9 Issue 1, p1-11. 11p.

Cumulative Incidence in Monogenic Alzheimer's Disease and Frontotemporal Dementia: Gene–Gene Interaction Effect.

Authors: Geviti, Andrea Pagano, Lorenzo Grassi, Mario et al.

Source: International Journal of Molecular Sciences. May2026, Vol. 27 Issue 9, p4081. 16p.

Epistasis Effects of Chalkiness and Application Using Marker-Assisted Recurrent Selection in Indica Rice.

Authors: Gu, Wenbin Fu, Lumei Wang, Xinjian et al.

Source: Agronomy. Apr2026, Vol. 16 Issue 8, p792. 17p.

Genetic Variations and Epistatic Interactions for Agronomic and Yield Traits in Winter Wheat Population Derived from 'TAM 204' and 'Iba' Cultivars.

Authors: Rauf, Yahya Valenzuela-Antelo, Jorge Luis Dogan, Mehmet et al.

Source: Agronomy. Apr2026, Vol. 16 Issue 7, p755. 20p.

D-LIM: A neural network for interpretable gene–gene interactions.

Authors: Wang, Shuhui Allauzen, Alexandre Nghe, Philippe et al.

Source: PLoS Computational Biology. 3/23/2026, Vol. 22 Issue 3, p1-22. 22p.

Epistasis mediates the role of negative frequency-dependent selection in bacterial strain structure.

Authors: Guillemet, Martin Lehtinen, Sonja

Source: PLoS Computational Biology. 3/19/2026, Vol. 22 Issue 3, p1-22. 22p.

Functional bottlenecks can emerge from non-epistatic underlying traits.

Authors: Schulte, Anna Ottavia Alqatari, Samar Rossi, Saverio et al.

Source: PLoS Computational Biology. 3/16/2026, Vol. 22 Issue 3, p1-20. 20p.

Free energy perturbations in enzyme kinetic models reveal cryptic epistasis.

Authors: Buda, Karol Tokuriki, Nobuhiko

Source: PLoS Computational Biology. 3/11/2026, Vol. 22 Issue 3, p1-16. 16p.

Inheritance Pattern of Yield and its Components in Brinjal (Solanum melongena L.) Through Generation Mean Analysis.

Authors: Yasaswini, M. Chetariya, C. P. Delvadiya, I. R. et al.

Source: Indian Journal of Agricultural Research. Mar2026, Vol. 60 Issue 3, p353-358. 6p.

Genetics and Gene Effects of Quantitative Traits in Bread Wheat (Triticum aestivum L.) Under the Mid‐Hill Zone of the Northwestern Himalayas.

Authors: Batheja, Aashima Vekariya, Rajesh D. Rana, Vijay et al.

Source: International Journal of Agronomy. 2/23/2026, Vol. 2026, p1-12. 12p.

Structural ontogeny of protein-protein interactions.

Authors: Yang, Aerin Jiang, Hanlun Jude, Kevin M. et al.

Source: Science. 2/12/2026, Vol. 391 Issue 6786, p1-18. 18p.

Subjects: Protein-protein interactions, Coevolution, Epistasis (Genetics), Binding sites, Machine learning, Molecular docking, Drug discovery

Applying gradient tree boosting to QTL mapping with Shapley additive explanations.

Authors: Ishibashi, Tomohiro Onogi, Akio

Source: Breeding Science. 2025, Vol. 75 Issue 5, p378-391. 14p.

Nonlinear kernel-based high-dimensional inference for set-based genetic association studies.

Authors: Zhang, Zechen Yang, Hui Zhu, Meilin et al.

Source: Briefings in Bioinformatics. May2026, Vol. 27 Issue 3, p1-12. 12p.

QTLNetwork-MP: integrative mapping of additive, epistatic, and G × E effects for complex traits in multiparent advanced generation intercross populations.

Authors: Zhu, Tian- Neng Tong, Zhijun Suo, Mingzhe et al.

Source: Briefings in Bioinformatics. May2026, Vol. 27 Issue 3, p1-12. 12p.

How far can you go? Extrapolating values of catalytic activity from known protein landscapes in natural and directed evolution.

Authors: Kell, Douglas B. Roberts, Ivayla

Source: Chemical Society Reviews. 6/8/2026, Vol. 55 Issue 11, p6417-6452. 36p.

Subjects: Catalytic activity, Epistasis (Genetics), Protein engineering, Machine learning, Biocatalysis, Statistical models

Exploring weighting schemes for the discovery of informative generalized between pathway models to uncover pathways in genetic interaction networks.

Authors: M. Yu, Kevin J. Cowen, Lenore

Source: Scientific Reports. 8/18/2025, Vol. 15 Issue 1, p1-11. 11p.