Search Results - "Epoxide hydrolase"

EPHX2 Orchestrates Intestinal Epithelial Barrier Repair in Ulcerative Colitis: An Integrated Multi‐Omics and Experimental Study.

Authors: Dai, Tian Han, Siyu Hu, Xiaoping et al.

Source: CTS: Clinical & Translational Science. Jul2026, Vol. 19 Issue 7, p1-13. 13p.

Soluble Epoxide Hydrolase Inhibition Improves Alzheimer's Disease Hallmarks: Correlation with Peripheral Inflammation and Gut Microbiota Modulation.

Authors: Jarne-Ferrer, Júlia Griñán-Ferré, Christian Jora, Beatrice et al.

Source: Aging & Disease. Apr2026, Vol. 17 Issue 2, p1131-1154. 24p.

Transplantation of Soluble Epoxide Hydrolase Inhibitor-Treated Human Brown Adipocytes Promotes Adipose Tissue Activation in High-Fat-Diet-Fed Nude Mice.

Authors: Wu, Haoying Xu, Xinyun Chen, Jiangang et al.

Source: International Journal of Molecular Sciences. Feb2026, Vol. 27 Issue 3, p1440. 21p.

Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain.

Authors: Codony, Sandra Jora, Beatrice Santos-Caballero, Miriam et al.

Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2025, Vol. 40 Issue 1, p1-24. 24p.

Immobilization and Catalytic Properties of Limonene-1,2-Epoxide Hydrolase.

Authors: Kaniaková, Katarína Hronská, Helena Petrovičová, Tatiana et al.

Source: Catalysts (2073-4344). Oct2025, Vol. 15 Issue 10, p986. 20p.

Synthesis, molecular docking, and in vitro evaluation of 2,4-dichlorobenzylamide derivatives as soluble epoxide hydrolase (sEH) inhibitors.

Authors: Çalışkan, Kübra Sadak, Esra Jordan, Paul M. et al.

Source: Organic Communications. Jul-Sep2025, Vol. 18 Issue 3, p166-176. 11p.

Inhibition of Soluble Epoxide Hydrolase Prevents Docetaxel-Induced Painful Peripheral Neuropathy.

Authors: Wagner, Karen M. Yang, Jun Morisseau, Christophe et al.

Source: International Journal of Molecular Sciences. Jun2025, Vol. 26 Issue 12, p5630. 22p.

Integrative Analysis of EPHX4 as a Novel Prognostic and Diagnostic Biomarker in Lung Adenocarcinoma.

Authors: Liu, Pengze Chen, Yutong

Source: International Journal of Molecular Sciences. Jun2025, Vol. 26 Issue 11, p5095. 19p.

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Environmental risk and genetic susceptibility in Alzheimer's disease: Impacts on cognitive function and biomarkers.

Authors: Kanani, Khushi Ramakrishnan, Prevena Neupane, Snabu et al.

Source: Journal of Alzheimer's Disease. Jul2026, Vol. 112 Issue 1, p333-344. 12p.

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Inhibition of soluble epoxide hydrolase confers neuroprotection and restores microglial homeostasis in a tauopathy mouse model.

Authors: Wang, Shuo Qi, Chuangye Rajpurohit, Chetan et al.

Source: Molecular Neurodegeneration. 4/23/2025, Vol. 20 Issue 1, p1-19. 19p.

Synthetic Epoxyeicosatrienoic Acid Mimics Protect Mesangial Cells from Sorafenib-Induced Cell Death.

Authors: de Bourg, Marcus Mishra, Abhishek Mohammad, Rawand S. et al.

Source: Molecules. Apr2025, Vol. 30 Issue 7, p1445. 27p.

A Soluble Epoxide Hydrolase Inhibitor Improves Cerebrovascular Dysfunction, Neuroinflammation, Amyloid Burden, and Cognitive Impairments in the hAPP/PS1 TgF344-AD Rat Model of Alzheimer's Disease.

Authors: Fang, Xing Border, Jane J. Zhang, Huawei et al.

Source: International Journal of Molecular Sciences. Mar2025, Vol. 26 Issue 6, p2433. 25p.

A highly efficient chemoenzymatic process to produce (R)-6,7-dihydroxygeraniol.

Authors: Pienaar, Daniel P. Mitra, Robin K. Botes, Adriana L. et al.

Source: Biocatalysis & Biotransformation. Feb2025, Vol. 43 Issue 1, p109-116. 8p.

Subjects: Epoxide hydrolase, Biochemical substrates, Biocatalysis, Epoxidation, Hydrolysis

Sodium alginate-immobilized epoxide hydrolase: A multifaceted strategy for enhanced stability, reusability, and catalytic performance.

Authors: Yu, Zongzhong Zhu, Meinan Gu, Xiao et al.

Source: Journal of Biotechnology. Feb2026, Vol. 410, p84-95. 12p.

Subjects: Sodium alginate, Epoxide hydrolase, Biocompatibility, Immobilized enzymes, Enzyme regulation, Mathematical optimization

Intradomain Allosteric Regulation of Soluble Epoxide Hydrolase by Its Substrates.

Authors: Matsumura, Shin Shida, Ayano Tsuchii, Moeno et al.

Source: International Journal of Molecular Sciences. Dec2024, Vol. 25 Issue 24, p13496. 11p.

A quantum leap at a time: In memory of Bruce D. Hammock.

Authors: Lea, Walter S.¹ wsleal@ucdavis.edu

Source: Proceedings of the National Academy of Sciences of the United States of America. 3/3/2026, Vol. 123 Issue 9, p1-3. 3p.

Subjects: Epoxide hydrolase, Inflammation, Mentoring, Immunochemistry, Juvenile hormones, Entomology, Biomarkers

Omega-6/omega-3 oxylipin imbalance and altered 15-LOX and sEH pathways in Fontan physiology.

Authors: Caligiuri, Stephanie P. B. Ravandi, Amir Aukema, Harold M. et al.

Source: American Journal of Physiology: Heart & Circulatory Physiology. May2026, Vol. 330 Issue 5, p1-13. 13p.

Epoxide Hydrolase Family: Biological Functions, Disease Mechanisms, and Emerging Therapeutic Strategies.

Authors: Tan, Yadan Xu, Jingjing Huang, Ziteng et al.

Source: Biology (2079-7737). May2026, Vol. 15 Issue 9, p691. 23p.