Search Results - "Faille, Alexandre"

Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate.

Authors: Ko, Donghwi Ruonala, Raili Faille, Alexandre et al.

Source: Science. 2/12/2026, Vol. 391 Issue 6786, p694-699. 6p.

Subjects: RNA methylation, Xylem, Polyamines, Cell differentiation, Arabidopsis, Peptide bonds, Protein synthesis

Prothrombinase processivity is conferred by substrate allostery.

Authors: Üstok, Fatma Işık Faille, Alexandre Warren, Alan J et al.

Source: EMBO Journal. Jun2026, Vol. 45 Issue 11, p3954-3977. 24p.

Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.

Authors: Zyryanova, Alisa F. Weis, Félix Faille, Alexandre et al.

Source: Science (pre-March 2025). 3/30/2018, Vol. 359 Issue 6383, p1533-1536. 4p. 3 Diagrams.

Subjects: Translation initiation factors (Biochemistry), Guanine nucleotide exchange factors, Phosphorylation, Neurodegeneration, Mutagenesis, Prevention

Teaching old drugs new tricks.

Authors: FAILLE, ALEXANDRE WARREN, ALAN J.

Source: eLife. 12/8/2022, p1-3. 3p.

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Detection of soluble co-factor dependent protein expression in vivo: Application to the 4′-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis.

Authors: Rottier, Karine Faille, Alexandre Prudhomme, Thomas et al.

Source: Journal of Structural Biology. Sep2013, Vol. 183 Issue 3, p320-328. 9p.

Subjects: Gene expression in bacteria, Phosphopantetheine, Mycobacterium tuberculosis, Transferases, Cofactors (Biochemistry), Escherichia coli, Precipitation (Chemistry), Polyketide synthases

Direct targeted therapy for MLL‐fusion‐driven high‐risk acute leukaemias.

Authors: Cantilena, Sandra Gasparoli, Luca Pal, Deepali et al.

Source: Clinical & Translational Medicine. Jun2022, Vol. 12 Issue 6, p1-19. 19p.

A 3.3-Å cryo-EM structure of an engineered high-affinity human prothrombinase complex.

Authors: Üstok FI Faille A Huntington JA

Source: Blood [Blood] 2026 Jan 29; Vol. 147 (5), pp. 573-583.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

Serious issues with cryo-EM structures of human prothrombinase.

Authors: Huntington JA Faille A Ustok FI

Source: Open biology [Open Biol] 2025 Jan; Vol. 15 (1), pp. 240193. Date of Electronic Publication: 2025 Jan 22.

Publication Type: Journal Article; Review

Journal Info: Publisher: Royal Society Pub Country of Publication: England NLM ID: 101580419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2046-2441 (Electronic) Linking ISSN: 20462441 NLM ISO Abbreviation: Open Biol Subsets: MEDLINE

Publisher Correction: Somatic genetic rescue of a germline ribosome assembly defect.

Authors: Tan S Kermasson L Hilcenko C et al.

Source: Nature communications [Nat Commun] 2022 Jun 22; Vol. 13 (1), pp. 3574. Date of Electronic Publication: 2022 Jun 22.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE; PubMed not MEDLINE

eIF6 rebinding dynamically couples ribosome maturation and translation.

Authors: Jaako P Faille A Tan S et al.

Source: Nature communications [Nat Commun] 2022 Mar 23; Vol. 13 (1), pp. 1562. Date of Electronic Publication: 2022 Mar 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Somatic genetic rescue of a germline ribosome assembly defect.

Authors: Tan S Kermasson L Hilcenko C et al.

Source: Nature communications [Nat Commun] 2021 Aug 19; Vol. 12 (1), pp. 5044. Date of Electronic Publication: 2021 Aug 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

The chemical landscape of the human ribosome at 1.67 Å resolution.

Authors: Faille A Dent KC Pellegrino S et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2023 Feb 28. Date of Electronic Publication: 2023 Feb 28.

Publication Type: Preprint; Journal Article

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Hemocyte siRNA uptake is increased by 5' cholesterol-TEG addition in Biomphalaria glabrata, snail vector of schistosome.

Authors: Portet A Galinier R Lassalle D et al.

Source: PeerJ [PeerJ] 2021 Feb 23; Vol. 9, pp. e10895. Date of Electronic Publication: 2021 Feb 23 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: PeerJ Inc Country of Publication: United States NLM ID: 101603425 Publication Model: eCollection Cited Medium: Print ISSN: 2167-8359 (Print) Linking ISSN: 21678359 NLM ISO Abbreviation: PeerJ Subsets: PubMed not MEDLINE

Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases.

Authors: Grabowska AD Brison Y Maveyraud L et al.

Source: ACS chemical biology [ACS Chem Biol] 2020 Dec 18; Vol. 15 (12), pp. 3206-3216. Date of Electronic Publication: 2020 Nov 25.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Experimental mapping of soluble protein domains using a hierarchical approach.

Authors: Pedelacq JD Nguyen HB Cabantous S et al.

Source: Nucleic acids research [Nucleic Acids Res] 2011 Oct; Vol. 39 (18), pp. e125. Date of Electronic Publication: 2011 Jul 19.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Validation Study

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

EFL1 mutations impair eIF6 release to cause Shwachman-Diamond syndrome.

Authors: Tan S Kermasson L Hoslin A et al.

Source: Blood [Blood] 2019 Jul 18; Vol. 134 (3), pp. 277-290. Date of Electronic Publication: 2019 May 31.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.

Authors: Kargas V Castro-Hartmann P Escudero-Urquijo N et al.

Source: ELife [Elife] 2019 May 22; Vol. 8. Date of Electronic Publication: 2019 May 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE