Search Results - "Farnsworth DA"

ERKed by too much signaling: from oncogenic driver to therapeutic vulnerability.

Authors: Farnsworth DA Naznin F Subramaniam A et al.

Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Mar 21; Vol. 83 (1). Date of Electronic Publication: 2026 Mar 21.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE

Drug tolerance and persistence to EGFR inhibitor treatment are mediated by an ILK-SFK-YAP signaling axis in lung adenocarcinoma.

Authors: Shi R Farnsworth DA Febres-Aldana CA et al.

Source: Oncogene [Oncogene] 2025 Aug; Vol. 44 (32), pp. 2831-2849. Date of Electronic Publication: 2025 May 31.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

Reactivation of DRP1 plays a functional role in resistance to MEK inhibition in pancreatic cancer cells.

Authors: Sharmin S Kashatus JA Adair SJ et al.

Source: British journal of cancer [Br J Cancer] 2026 Jul 14. Date of Electronic Publication: 2026 Jul 14.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE

Redox-modulation of regulated cell death: implications for synergistic anticancer therapies.

Authors: Singh P Sridhar S Balasubramanian D et al.

Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Jul; Vol. 399 (10), pp. 14807-14841. Date of Electronic Publication: 2026 May 08.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE

Increased mRNA translation delays tumour initiation and exposes a therapeutic vulnerability in lung cancer.

Authors: Pardo L Moore M Deshmukh R et al.

Source: Molecular cancer [Mol Cancer] 2026 May 21; Vol. 25 (1). Date of Electronic Publication: 2026 May 21.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE

Vaccinia-related kinase 2 inhibition elicits vulnerability of glutathione metabolism in pancreatic cancer.

Authors: Chen S Fu X Zhang T et al.

Source: Cell death & disease [Cell Death Dis] 2026 Mar 19; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 19.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

Tumor-intrinsic metabolic pathways essential for tumorigenesis and resistance to anti-PD1 in oncogenic Kras-driven lung adenocarcinoma.

Authors: Vasan K Chalmers ZR Kong H et al.

Source: Cancer & metabolism [Cancer Metab] 2026 Mar 16; Vol. 14 (1). Date of Electronic Publication: 2026 Mar 16.

Publication Type: Journal Article

Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101607582 Publication Model: Electronic Cited Medium: Print ISSN: 2049-3002 (Print) Linking ISSN: 20493002 NLM ISO Abbreviation: Cancer Metab Subsets: PubMed not MEDLINE

Emerging Anti-Cancer and Repurposed Therapies for Overcoming Multidrug Resistance in Lung Cancer.

Authors: Solanki N Shah P Kewalramani S et al.

Source: Medical oncology (Northwood, London, England) [Med Oncol] 2025 Dec 26; Vol. 43 (2), pp. 100. Date of Electronic Publication: 2025 Dec 26.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 9435512 Publication Model: Electronic Cited Medium: Internet ISSN: 1559-131X (Electronic) Linking ISSN: 13570560 NLM ISO Abbreviation: Med Oncol Subsets: MEDLINE

Pharmacological assessment of disulfide–triazine hybrids: synthesis, enzyme inhibition, and molecular docking study.

Authors: Türkan, Fikret Cetin, Adnan Rozbicki, Przemysław et al.

Source: Medicinal Chemistry Research. Jul2024, Vol. 33 Issue 7, p1205-1217. 13p.

DNA replication stress and mitotic catastrophe mediate sotorasib addiction in KRAS^G12C-mutant cancer.

Authors: Chiou, Li-Wen Chan, Chien-Hui Jhuang, Yu-Ling et al.

Source: Journal of Biomedical Science. 6/29/2023, Vol. 30 Issue 1, p1-18. 18p.

Drug-tolerant persister cells in cancer: a scoping review of definitions, models, and molecular mechanisms.

Authors: Lopez-Gonzalez JS Perez-Medina M Galicia-Velasco M et al.

Source: Frontiers in oncology [Front Oncol] 2026 Apr 29; Vol. 16, pp. 1771061. Date of Electronic Publication: 2026 Apr 29 (Print Publication: 2026).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE

Extracellular Vesicles from Lung Adenocarcinoma Cells Induce Activation of Different Cancer-Associated Fibroblast Subtypes.

Authors: Trejo Vazquez JA Towle R Farnsworth DA et al.

Source: Biomedicines [Biomedicines] 2024 Nov 04; Vol. 12 (11). Date of Electronic Publication: 2024 Nov 04.

Publication Type: Journal Article

Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101691304 Publication Model: Electronic Cited Medium: Print ISSN: 2227-9059 (Print) Linking ISSN: 22279059 NLM ISO Abbreviation: Biomedicines Subsets: PubMed not MEDLINE

MEK inhibitor resistance in lung adenocarcinoma is associated with addiction to sustained ERK suppression.

Authors: Farnsworth DA Inoue Y Johnson FD et al.

Source: NPJ precision oncology [NPJ Precis Oncol] 2022 Nov 23; Vol. 6 (1), pp. 88. Date of Electronic Publication: 2022 Nov 23.

Publication Type: Journal Article

Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology.

Authors: Dang M Schritz A Goncharenko N et al.

Source: Molecular oncology [Mol Oncol] 2025 May; Vol. 19 (5), pp. 1508-1516. Date of Electronic Publication: 2024 Dec 11.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE

Integrative single-cell RNA-seq and spatial transcriptomics analyses reveal diverse apoptosis-related gene expression profiles in EGFR-mutated lung cancer.

Authors: Izumi M Fujii M Kobayashi IS et al.

Source: Cell death & disease [Cell Death Dis] 2024 Aug 09; Vol. 15 (8), pp. 580. Date of Electronic Publication: 2024 Aug 09.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

DUSP22 inhibits lung tumorigenesis by suppression of EGFR/c-Met signaling.

Authors: Lin HH Chang CW Liao YT et al.

Source: Cell death discovery [Cell Death Discov] 2024 Jun 14; Vol. 10 (1), pp. 285. Date of Electronic Publication: 2024 Jun 14.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE

Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines.

Authors: Kocher D Cao L Guiho R et al.

Source: Journal of neuro-oncology [J Neurooncol] 2024 Jun; Vol. 168 (2), pp. 317-332. Date of Electronic Publication: 2024 Apr 17.

Publication Type: Journal Article

Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 8309335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7373 (Electronic) Linking ISSN: 0167594X NLM ISO Abbreviation: J Neurooncol Subsets: MEDLINE

The two sides of chromosomal instability: drivers and brakes in cancer.

Authors: Hosea R Hillary S Naqvi S et al.

Source: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2024 Mar 29; Vol. 9 (1), pp. 75. Date of Electronic Publication: 2024 Mar 29.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE