Search Results - "Fast W"

Discovery and characterization of a covalent inhibitor of New Delhi metallo β-lactamase.

Authors: Rivera DD Schroeder JM Walker JN et al.

Source: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2026 Jul; Vol. 781, pp. 110805. Date of Electronic Publication: 2026 Apr 07.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

Emergence and characterization of lipidated β-lactamases.

Authors: Smisek T Fast W Whitman CP

Source: Archives of biochemistry and biophysics [Arch Biochem Biophys] 2026 Jan; Vol. 775, pp. 110644. Date of Electronic Publication: 2025 Nov 03.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372430 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0384 (Electronic) Linking ISSN: 00039861 NLM ISO Abbreviation: Arch Biochem Biophys Subsets: MEDLINE

Inhibitor Affinity Differs among Clinical Variants of IMP Metallo-β-Lactamases: Analysis and Implications for Inhibitor Design.

Authors: Thomas CA Alao JP Smisek T et al.

Source: ACS infectious diseases [ACS Infect Dis] 2025 Aug 08; Vol. 11 (8), pp. 2157-2168. Date of Electronic Publication: 2025 Jul 24.

Publication Type: Journal Article

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

Characterization of Lipidated New Delhi Metallo-β-lactamase Using Synthetic Nanodiscs.

Authors: Smisek T Vuksanovic N Walker JN et al.

Source: Biochemistry [Biochemistry] 2025 Jun 17; Vol. 64 (12), pp. 2679-2696. Date of Electronic Publication: 2025 Jun 03.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

PHD2 enzyme is an intracellular manganese sensor that initiates the homeostatic response against elevated manganese.

Authors: Gurol KC Jursa T Cho EJ et al.

Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jun 25; Vol. 121 (26), pp. e2402538121. Date of Electronic Publication: 2024 Jun 21.

Publication Type: Journal Article

Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase.

Authors: Cheng Z Aitha M Thomas CA et al.

Source: Journal of chemical information and modeling [J Chem Inf Model] 2024 May 27; Vol. 64 (10), pp. 3977-3991. Date of Electronic Publication: 2024 May 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

Iminodiacetic Acid as a Novel Metal-Binding Pharmacophore for New Delhi Metallo-β-lactamase Inhibitor Development.

Authors: Chen AY Thomas CA Thomas PW et al.

Source: ChemMedChem [ChemMedChem] 2020 Jul 20; Vol. 15 (14), pp. 1272-1282. Date of Electronic Publication: 2020 May 07.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

Asymmetric dimethylarginine positively modulates calcium-sensing receptor signalling to promote lipid accumulation.

Authors: Dowsett L Duluc L Higgins E et al.

Source: Cellular signalling [Cell Signal] 2023 Jul; Vol. 107, pp. 110676. Date of Electronic Publication: 2023 Apr 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3913 (Electronic) Linking ISSN: 08986568 NLM ISO Abbreviation: Cell Signal Subsets: MEDLINE

Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo-β-Lactamases.

Authors: Chen AY Thomas PW Cheng Z et al.

Source: ChemMedChem [ChemMedChem] 2019 Jul 03; Vol. 14 (13), pp. 1271-1282. Date of Electronic Publication: 2019 May 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

Structural insights into the design of reversible fluorescent probes for metallo-β-lactamases NDM-1, VIM-2, and IMP-1.

Authors: Price S Mehta R Tan D et al.

Source: Journal of inorganic biochemistry [J Inorg Biochem] 2022 Aug; Vol. 233, pp. 111869. Date of Electronic Publication: 2022 May 20.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7905788 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3344 (Electronic) Linking ISSN: 01620134 NLM ISO Abbreviation: J Inorg Biochem Subsets: MEDLINE

Selective Covalent Protein Modification by 4-Halopyridines through Catalysis.

Authors: Schardon CL Tuley A Er JAV et al.

Source: Chembiochem : a European journal of chemical biology [Chembiochem] 2017 Aug 04; Vol. 18 (15), pp. 1551-1556. Date of Electronic Publication: 2017 Jun 27.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE

On the kinetic mechanism of dimethylarginine dimethylaminohydrolase.

Authors: Johnson CM Fast W

Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2022 Jul 15; Vol. 66, pp. 116816. Date of Electronic Publication: 2022 May 13.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Discovery of an Effective Small-Molecule Allosteric Inhibitor of New Delhi Metallo-β-lactamase (NDM).

Authors: Thomas PW Cho EJ Bethel CR et al.

Source: ACS infectious diseases [ACS Infect Dis] 2022 Apr 08; Vol. 8 (4), pp. 811-824. Date of Electronic Publication: 2022 Mar 30.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

Visualizing the Dynamic Metalation State of New Delhi Metallo-β-lactamase-1 in Bacteria Using a Reversible Fluorescent Probe.

Authors: Mehta R Rivera DD Reilley DJ et al.

Source: Journal of the American Chemical Society [J Am Chem Soc] 2021 Jun 09; Vol. 143 (22), pp. 8314-8323. Date of Electronic Publication: 2021 May 26.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

Cyclobutanone Inhibitor of Cobalt-Functionalized Metallo-γ-Lactonase AiiA with Cyclobutanone Ring Opening in the Active Site.

Authors: Reidl CT Mascarenhas R Mohammad TSH et al.

Source: ACS omega [ACS Omega] 2021 May 17; Vol. 6 (21), pp. 13567-13578. Date of Electronic Publication: 2021 May 17 (Print Publication: 2021).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE

Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants.

Authors: Cheng Z Bethel CR Thomas PW et al.

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2021 Mar 18; Vol. 65 (4). Date of Electronic Publication: 2021 Mar 18 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

Discovery of 4,4'-Dipyridylsulfide Analogs as "Switchable Electrophiles" for Covalent Inhibition.

Authors: Ahn YC May VK Bedford GC et al.

Source: ACS chemical biology [ACS Chem Biol] 2021 Feb 19; Vol. 16 (2), pp. 264-269. Date of Electronic Publication: 2021 Jan 25.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

Elusive structural changes of New Delhi metallo-β-lactamase revealed by ultraviolet photodissociation mass spectrometry.

Authors: Mehaffey MR Ahn YC Rivera DD et al.

Source: Chemical science [Chem Sci] 2020 Aug 11; Vol. 11 (33), pp. 8999-9010. Date of Electronic Publication: 2020 Aug 11.

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101545951 Publication Model: Electronic Cited Medium: Print ISSN: 2041-6520 (Print) Linking ISSN: 20416520 NLM ISO Abbreviation: Chem Sci Subsets: PubMed not MEDLINE

Covalent inhibition of New Delhi metallo-β-lactamase-1 (NDM-1) by cefaclor.

Authors: Thomas PW Cammarata M Brodbelt JS et al.

Source: Chembiochem : a European journal of chemical biology [Chembiochem] 2014 Nov 24; Vol. 15 (17), pp. 2541-8. Date of Electronic Publication: 2014 Oct 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE

Developing an irreversible inhibitor of human DDAH-1, an enzyme upregulated in melanoma.

Authors: Wang Y Hu S Gabisi AM Jr et al.

Source: ChemMedChem [ChemMedChem] 2014 Apr; Vol. 9 (4), pp. 792-7. Date of Electronic Publication: 2014 Feb 26.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE