Search Results - "Foley CM"

Non-invasive, home cage digital monitoring for improved safety pharmacology assessments in drug development: ICH S7A update considerations.

Authors: Berridge BR Liu CN Cherian AK et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2026 Jun 01; Vol. 140, pp. 108430. Date of Electronic Publication: 2026 Jun 01.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Histopathologic Findings in the Heart Associated With Telemetry Instrumentation in Beagle Dogs.

Authors: Kohnken R Wilsey A Bird B et al.

Source: Toxicologic pathology [Toxicol Pathol] 2025 Oct; Vol. 53 (7), pp. 626-629. Date of Electronic Publication: 2025 Aug 19.

Publication Type: Journal Article

Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 7905907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-1601 (Electronic) Linking ISSN: 01926233 NLM ISO Abbreviation: Toxicol Pathol Subsets: MEDLINE

Advancing nonclinical blood pressure assessment: Current practices and future directions in drug development.

Authors: Pugsley MK Bhatt S Gottfridsson C et al.

Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2026 Aug; Vol. 169, pp. 106098. Date of Electronic Publication: 2026 Apr 14.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE

ABBV-712-induced cardiac pathology in rats is related to off-target-driven acute vasodilation, tachycardia, and increased cardiac contractility.

Authors: Kohnken R Fossey S Buck WR et al.

Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2025 May 01; Vol. 205 (1), pp. 233-244.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

Benign cardiac troponin I release induced by elevated beat rate is associated with membrane bleb formation.

Authors: Hatahet J Nonarath HJ Zafiratos MT et al.

Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2026 Feb; Vol. 507, pp. 117701. Date of Electronic Publication: 2025 Dec 30.

Publication Type: Journal Article

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0333 (Electronic) Linking ISSN: 0041008X NLM ISO Abbreviation: Toxicol Appl Pharmacol Subsets: MEDLINE

The Impact of Clinical Documentation Integrity Programs on Diagnosis Documentation.

Authors: Sanderson AL Lo L Arafiles W et al.

Source: Advances in health information science and practice [Adv Health Inf Sci Pract] 2025 Nov 19; Vol. 1 (2), pp. CGJA8827. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: American Health Information Management Association Country of Publication: United States NLM ID: 9919050935306676 Publication Model: eCollection Cited Medium: Internet ISSN: 3066-5825 (Electronic) Linking ISSN: 30665825 NLM ISO Abbreviation: Adv Health Inf Sci Pract Subsets: MEDLINE

Current practices on the measurement of electrocardiogram and hemodynamic parameters in non-rodent species in regulatory safety assessment studies.

Authors: Valentin JP Bourcier T Chi X et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2025 Sep; Vol. 135, pp. 107765. Date of Electronic Publication: 2025 Jun 19.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Preclinical cardiovascular safety assessment of pharmacology-toxicology relationship for a set of novel kinase inhibitors.

Authors: Koshman YE Kohnken R Logan MR et al.

Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2024 Mar 26; Vol. 198 (2), pp. 316-327.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators.

Authors: Bian Z Schmidt RG Wilson NS et al.

Source: Journal of medicinal chemistry [J Med Chem] 2025 Jul 24; Vol. 68 (14), pp. 14357-14383. Date of Electronic Publication: 2025 Jul 09.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Reevaluating safety pharmacology respiratory studies within the ICH S7A core battery: A multi-company evaluation of preclinical utility and clinical translation.

Authors: Friedrichs GS Abernathy MM Ackley D et al.

Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2024 Nov; Vol. 153, pp. 105706. Date of Electronic Publication: 2024 Sep 16.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE

Patients' experiences and perspectives of patient-reported outcome measures in clinical care: A systematic review and qualitative meta-synthesis.

Authors: Carfora L Foley CM Hagi-Diakou P et al.

Source: PloS one [PLoS One] 2022 Apr 21; Vol. 17 (4), pp. e0267030. Date of Electronic Publication: 2022 Apr 21 (Print Publication: 2022).

Publication Type: Journal Article; Systematic Review

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Innovative approaches to cardiovascular safety pharmacology assessment.

Authors: Pugsley MK Winters BR Koshman YE et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2024 Jul-Aug; Vol. 128, pp. 107533. Date of Electronic Publication: 2024 Jun 28.

Publication Type: Editorial; Introductory Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Improving the in vivo QTc assay: Nonclinical concentration-QTc modeling for risk assessment.

Authors: Wisialowski TA Ether N Foley CM et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2024 Jul-Aug; Vol. 128, pp. 107515. Date of Electronic Publication: 2024 May 20.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Development of a pharmaceutical database as an aid to the nonclinical detection of drug-induced cardiac toxicity.

Authors: De Alwis D Foley CM Herman E et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2024 May-Jun; Vol. 127, pp. 107507. Date of Electronic Publication: 2024 Apr 16.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Evaluation of the translation of multiple cardiovascular regulatory mechanisms in the anesthetized dog.

Authors: Antic O Koshman YE Bird BM et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2024 Mar-Apr; Vol. 126, pp. 107497. Date of Electronic Publication: 2024 Mar 11.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Keto-Sleuths - An Unusual Cause of Loss of Ketosis?

Authors: Foley CM Ryan C Tarrant S et al.

Source: Child neurology open [Child Neurol Open] 2021 Jul 23; Vol. 8, pp. 2329048X211029736. Date of Electronic Publication: 2021 Jul 23 (Print Publication: 2021).

Publication Type: Case Reports; Journal Article

Journal Info: Publisher: SAGE Publications Inc Country of Publication: United States NLM ID: 101691975 Publication Model: eCollection Cited Medium: Internet ISSN: 2329-048X (Electronic) Linking ISSN: 2329048X NLM ISO Abbreviation: Child Neurol Open Subsets: PubMed not MEDLINE

Systemic juvenile idiopathic arthritis: The Great Ormond Street Hospital experience (2005-2021).

Authors: Foley CM McKenna D Gallagher K et al.

Source: Frontiers in pediatrics [Front Pediatr] 2023 Sep 12; Vol. 11, pp. 1218312. Date of Electronic Publication: 2023 Sep 12 (Print Publication: 2023).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101615492 Publication Model: eCollection Cited Medium: Print ISSN: 2296-2360 (Print) Linking ISSN: 22962360 NLM ISO Abbreviation: Front Pediatr Subsets: PubMed not MEDLINE

Safety pharmacology 2023 and implementation of the ICH E14/S7B Q&A guidance document.

Authors: Pugsley MK Koshman YE Foley CM et al.

Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2023 Sep-Oct; Vol. 123, pp. 107300. Date of Electronic Publication: 2023 Jul 29.

Publication Type: Editorial

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes.

Authors: Ribeiro AJS Guth BD Engwall M et al.

Source: Frontiers in pharmacology [Front Pharmacol] 2019 Aug 29; Vol. 10, pp. 934. Date of Electronic Publication: 2019 Aug 29 (Print Publication: 2019).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Adverse Drug-Induced Inotropic Effects in Early Drug Development. Part 1: General Considerations for Development of Novel Testing Platforms.

Authors: Guth BD Engwall M Eldridge S et al.

Source: Frontiers in pharmacology [Front Pharmacol] 2019 Aug 09; Vol. 10, pp. 884. Date of Electronic Publication: 2019 Aug 09 (Print Publication: 2019).

Publication Type: Journal Article; Review

Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE