Search Results - "Foley TL"

Discovery of an ITK and TRK kinase inhibitor for the potential topical treatment of atopic dermatitis.

Authors: Duffen JL Crouse KK Ji L et al.

Source: Nature communications [Nat Commun] 2026 Mar 09; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 09.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Enabling Open Machine Learning of Deoxyribonucleic Acid-Encoded Library Selections to Accelerate the Discovery of Small Molecule Protein Binders.

Authors: Wellnitz J Ahmad S Bagale N et al.

Source: Journal of medicinal chemistry [J Med Chem] 2025 Oct 23; Vol. 68 (20), pp. 21635-21648. Date of Electronic Publication: 2025 Oct 06.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Fluorophosphonates on-Demand: A General and Simplified Approach toward Fluorophosphonate Synthesis.

Authors: Dutra JK Foley TL Huang Z et al.

Source: Chembiochem : a European journal of chemical biology [Chembiochem] 2021 May 14; Vol. 22 (10), pp. 1769-1774. Date of Electronic Publication: 2021 Mar 12.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 100937360 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-7633 (Electronic) Linking ISSN: 14394227 NLM ISO Abbreviation: Chembiochem Subsets: MEDLINE

Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery.

Authors: Coussens NP Sittampalam GS Guha R et al.

Source: Clinical and translational science [Clin Transl Sci] 2018 Sep; Vol. 11 (5), pp. 461-470. Date of Electronic Publication: 2018 Jul 24.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Review

Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci

Structural basis of the acyl-transfer mechanism of human GPAT1.

Authors: Johnson ZL Ammirati M Wasilko DJ et al.

Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2023 Jan; Vol. 30 (1), pp. 22-30. Date of Electronic Publication: 2022 Dec 15.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels.

Authors: Cherry JJ DiDonato CJ Androphy EJ et al.

Source: PloS one [PLoS One] 2017 Sep 25; Vol. 12 (9), pp. e0185079. Date of Electronic Publication: 2017 Sep 25 (Print Publication: 2017).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Understanding Data Noise and Uncertainty through Analysis of Replicate Samples in DNA-Encoded Library Selection.

Authors: Zhu H Foley TL Montgomery JI et al.

Source: Journal of chemical information and modeling [J Chem Inf Model] 2022 May 09; Vol. 62 (9), pp. 2239-2247. Date of Electronic Publication: 2021 Dec 04.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS).

Authors: Ratnayake AS Flanagan ME Foley TL et al.

Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2021 Jul 01; Vol. 41, pp. 116205. Date of Electronic Publication: 2021 May 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries.

Authors: Foley TL Burchett W Chen Q et al.

Source: SLAS discovery : advancing life sciences R & D [SLAS Discov] 2021 Feb; Vol. 26 (2), pp. 263-280. Date of Electronic Publication: 2021 Jan 08.

Publication Type: Journal Article

Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 101697563 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2472-5560 (Electronic) Linking ISSN: 24725552 NLM ISO Abbreviation: SLAS Discov Subsets: MEDLINE

A method for estimating binding affinity from primary DEL selection data.

Authors: Chen Q Hall J Foley TL et al.

Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Dec 03; Vol. 533 (2), pp. 249-255. Date of Electronic Publication: 2020 May 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

Fluorescent techniques for discovery and characterization of phosphopantetheinyl transferase inhibitors.

Authors: Kosa NM Foley TL Burkart MD

Source: The Journal of antibiotics [J Antibiot (Tokyo)] 2014 Jan; Vol. 67 (1), pp. 113-20. Date of Electronic Publication: 2013 Nov 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0151115 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1881-1469 (Electronic) Linking ISSN: 00218820 NLM ISO Abbreviation: J Antibiot (Tokyo) Subsets: MEDLINE

A simple method for determining compound affinity and chemical yield from DNA-encoded library selections.

Authors: Hall J Foley TL Chen Q et al.

Source: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Jun 18; Vol. 527 (1), pp. 250-256. Date of Electronic Publication: 2020 May 04.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

A Solution Phase Platform to Characterize Chemical Reaction Compatibility with DNA-Encoded Chemical Library Synthesis.

Authors: Ratnayake AS Flanagan ME Foley TL et al.

Source: ACS combinatorial science [ACS Comb Sci] 2019 Oct 14; Vol. 21 (10), pp. 650-655. Date of Electronic Publication: 2019 Sep 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101540531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2156-8944 (Electronic) Linking ISSN: 21568944 NLM ISO Abbreviation: ACS Comb Sci Subsets: MEDLINE

Phosphopantetheinyl transferase inhibition and secondary metabolism.

Authors: Foley TL Young BS Burkart MD

Source: The FEBS journal [FEBS J] 2009 Dec; Vol. 276 (23), pp. 7134-45. Date of Electronic Publication: 2009 Nov 06.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation.

Authors: McAllister LA Butler CR Mente S et al.

Source: Journal of medicinal chemistry [J Med Chem] 2018 Apr 12; Vol. 61 (7), pp. 3008-3026. Date of Electronic Publication: 2018 Mar 15.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase.

Authors: Butler CR Beck EM Harris A et al.

Source: Journal of medicinal chemistry [J Med Chem] 2017 Dec 14; Vol. 60 (23), pp. 9860-9873. Date of Electronic Publication: 2017 Dec 05.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA).

Authors: Gopalsamy A Narayanan A Liu S et al.

Source: Journal of medicinal chemistry [J Med Chem] 2017 Apr 13; Vol. 60 (7), pp. 3094-3108. Date of Electronic Publication: 2017 Mar 16.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

A Platform to Enable the Pharmacological Profiling of Small Molecules in Gel-Based Electrophoretic Mobility Shift Assays.

Authors: Foley TL Dorjsuren D Dexheimer TS et al.

Source: Journal of biomolecular screening [J Biomol Screen] 2016 Dec; Vol. 21 (10), pp. 1125-1131. Date of Electronic Publication: 2016 Jul 10.

Publication Type: Journal Article

Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 9612112 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-454X (Electronic) Linking ISSN: 10870571 NLM ISO Abbreviation: J Biomol Screen Subsets: MEDLINE

Covalent small molecule inhibitors of Ca(2+)-bound S100B.

Authors: Cavalier MC Pierce AD Wilder PT et al.

Source: Biochemistry [Biochemistry] 2014 Oct 28; Vol. 53 (42), pp. 6628-40. Date of Electronic Publication: 2014 Oct 14.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth.

Authors: Foley TL Rai G Yasgar A et al.

Source: Journal of medicinal chemistry [J Med Chem] 2014 Feb 13; Vol. 57 (3), pp. 1063-78. Date of Electronic Publication: 2014 Jan 22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE