Search Results - "Fraser JS"

Evaluating beta-tubulin variants as predictors of benzimidazole resistance across Caenorhabditis nematodes.

Authors: Shaver AO McKeown R Reyes Otero JM et al.

Source: PLoS pathogens [PLoS Pathog] 2026 Jun 05; Vol. 22 (6), pp. e1014306. Date of Electronic Publication: 2026 Jun 05 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

Mapping the avoid-ome: a systematic open-science approach to predictive ADMET.

Authors: Fraser JS Edgar S Handly LN et al.

Source: Nature communications [Nat Commun] 2026 May 25; Vol. 17 (1). Date of Electronic Publication: 2026 May 25.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Autoregulation of the MET receptor tyrosine kinase by its intracellular juxtamembrane domain.

Authors: Linossi EM Espinoza CA Estevam GO et al.

Source: The Biochemical journal [Biochem J] 2025 Dec 11; Vol. 482 (24).

Publication Type: Journal Article

Journal Info: Publisher: Published by Portland Press on behalf of the Biochemical Society Country of Publication: England NLM ID: 2984726R Publication Model: Print Cited Medium: Internet ISSN: 1470-8728 (Electronic) Linking ISSN: 02646021 NLM ISO Abbreviation: Biochem J Subsets: MEDLINE

Structural adaptations for enhanced translation kinetics in evolved ribosomes.

Authors: Raskar T Costello A Badran AH et al.

Source: Nucleic acids research [Nucleic Acids Res] 2026 Jul 17; Vol. 54 (14).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Emergence of specific binding and catalysis from a designed generalist binding protein.

Authors: Chen Y Bhattacharya S Bergmann L et al.

Source: Nature chemistry [Nat Chem] 2026 Jul; Vol. 18 (7), pp. 1334-1344. Date of Electronic Publication: 2026 May 04.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101499734 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1755-4349 (Electronic) Linking ISSN: 17554330 NLM ISO Abbreviation: Nat Chem Subsets: MEDLINE

Coronavirus protein interaction mapping in bat and human cells reveals network rewiring governing immune evasion and zoonotic potential.

Authors: Batra J Rutkowska M Zhou Y et al.

Source: Cell host & microbe [Cell Host Microbe] 2026 Jun 10; Vol. 34 (6), pp. 1100-1117.e13. Date of Electronic Publication: 2026 May 13.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101302316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1934-6069 (Electronic) Linking ISSN: 19313128 NLM ISO Abbreviation: Cell Host Microbe Subsets: MEDLINE

The Mac1 ADP-ribosylhydrolase is a therapeutic target for SARS-CoV-2.

Authors: Suryawanshi RK Jaishankar P Correy GJ et al.

Source: ELife [Elife] 2025 Nov 19; Vol. 14. Date of Electronic Publication: 2025 Nov 19.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Distal mutations enhance catalysis in designed enzymes by facilitating substrate binding and product release.

Authors: Zarifi N Asthana P Doustmohammadi H et al.

Source: Nature communications [Nat Commun] 2025 Sep 30; Vol. 16 (1), pp. 8662. Date of Electronic Publication: 2025 Sep 30.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Coupled equilibria of dimerization and lipid binding modulate SARS Cov 2 Orf9b interactions and interferon response.

Authors: San Felipe CJ Batra J Muralidharan M et al.

Source: ELife [Elife] 2025 Sep 17; Vol. 14. Date of Electronic Publication: 2025 Sep 17.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Structure-based design and synthesis of group A streptogramins that bind to the nascent peptide exit tunnel of the ribosome.

Authors: Lee IJ Li Q Raskar T et al.

Source: European journal of medicinal chemistry [Eur J Med Chem] 2026 Oct 15; Vol. 316, pp. 118947. Date of Electronic Publication: 2026 May 09.

Publication Type: Journal Article

Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation.

Authors: Guérin C Vinchent A Fernandes M et al.

Source: Molecular oncology [Mol Oncol] 2025 Aug; Vol. 19 (8), pp. 2366-2387. Date of Electronic Publication: 2025 Feb 20.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE

Expanding automated multiconformer ligand modeling to macrocycles and fragments.

Authors: Flowers J Echols N Correy GJ et al.

Source: ELife [Elife] 2025 Jun 30; Vol. 14. Date of Electronic Publication: 2025 Jun 30.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Toward a Random Background for Ligand Optimization.

Authors: Xu X Mailhot O Correy GJ et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 13. Date of Electronic Publication: 2026 May 13.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Inhibiting the interaction between the mitochondrial receptor Tom70 and SARS CoV 2 Orf9b with small molecules.

Authors: Felipe CS Verba KA Krogan NJ et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 27. Date of Electronic Publication: 2026 Apr 27.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA.

Authors: Bi Z Chen YX Young ID et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 23. Date of Electronic Publication: 2026 Apr 23.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

A Computational Community Blind Challenge on Pan-Coronavirus Drug Discovery Data.

Authors: MacDermott-Opeskin H Scheen J Wognum C et al.

Source: Journal of chemical information and modeling [J Chem Inf Model] 2026 Mar 23; Vol. 66 (6), pp. 3129-3149. Date of Electronic Publication: 2026 Feb 26.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

Structural adaptations for enhanced translation kinetics in evolved ribosomes.

Authors: Raskar T Costello A Badran AH et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Mar 06. Date of Electronic Publication: 2026 Mar 06.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Where and how to house big data on small fragments.

Authors: Erlanson DA Burley SK Fearon D et al.

Source: Nature communications [Nat Commun] 2025 May 05; Vol. 16 (1), pp. 4179. Date of Electronic Publication: 2025 May 05.

Publication Type: Journal Article; Review

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning.

Authors: Estevam GO Linossi E Rao J et al.

Source: ELife [Elife] 2025 Feb 17; Vol. 13. Date of Electronic Publication: 2025 Feb 17.

Publication Type: Journal Article

Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

Context-specific inhibition of mitochondrial ribosomes by phenicol and oxazolidinone antibiotics.

Authors: Bibel B Raskar T Couvillion M et al.

Source: Nucleic acids research [Nucleic Acids Res] 2025 Jan 24; Vol. 53 (3).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE