Search Results - "Freestone GC"

Conjugation to a transferrin receptor 1-binding Bicycle peptide enhances ASO and siRNA potency in skeletal and cardiac muscles.

Authors: Østergaard ME Carrer M Anderson BA et al.

Source: Nucleic acids research [Nucleic Acids Res] 2025 Apr 10; Vol. 53 (7).

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Synthesis, Incorporation, and Translation Properties of Threose Nucleic Acid Modified Trinucleotide Cap Analogs.

Authors: Pontarelli A Vasquez G Fu W et al.

Source: ACS omega [ACS Omega] 2025 Oct 27; Vol. 10 (44), pp. 53151-53162. Date of Electronic Publication: 2025 Oct 27 (Print Publication: 2025).

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE

Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides.

Authors: Anderson BA Freestone GC Low A et al.

Source: Nucleic acids research [Nucleic Acids Res] 2021 Sep 20; Vol. 49 (16), pp. 9026-9041.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Towards combining backbone and sugar constraint in 3'-3' bis-phosphonate tethered 2'-4' bridged LNA oligonucleotide trimers.

Authors: Duchamp E Vasquez G Firoozi N et al.

Source: RSC advances [RSC Adv] 2024 Jul 26; Vol. 14 (33), pp. 23583-23591. Date of Electronic Publication: 2024 Jul 26 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE

Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs.

Authors: Vasquez G Freestone GC Wan WB et al.

Source: Nucleic acids research [Nucleic Acids Res] 2021 Feb 26; Vol. 49 (4), pp. 1828-1839.

Publication Type: Journal Article

Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

Systematic Investigation of Tether Length and Phosphorus Configuration in Backbone Constrained Macrocyclic Nucleic Acids to Modulate Binding Kinetics for RNA.

Authors: Rajasekaran T Freestone GC Galindo-Murillo R et al.

Source: The Journal of organic chemistry [J Org Chem] 2023 Mar 17; Vol. 88 (6), pp. 3599-3614. Date of Electronic Publication: 2023 Mar 01.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE

Backbone Hydrocarbon-Constrained Nucleic Acids Modulate Hybridization Kinetics for RNA.

Authors: Rajasekaran T Freestone GC Galindo-Murillo R et al.

Source: Journal of the American Chemical Society [J Am Chem Soc] 2022 Feb 02; Vol. 144 (4), pp. 1941-1950. Date of Electronic Publication: 2022 Jan 18.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

Azetidine-based selective glycine transporter-1 (GlyT1) inhibitors with memory enhancing properties.

Authors: Hudson AR Santora VJ Petroski RE et al.

Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2020 Jul 15; Vol. 30 (14), pp. 127214. Date of Electronic Publication: 2020 Apr 25.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE

Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties.

Authors: Santora VJ Almos TA Barido R et al.

Source: Journal of medicinal chemistry [J Med Chem] 2018 Jul 26; Vol. 61 (14), pp. 6018-6033. Date of Electronic Publication: 2018 Jul 11.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

New synthetic technology for the construction of N-hydroxyindoles and synthesis of nocathiacin I model systems.

Authors: Nicolaou KC Estrada AA Freestone GC et al.

Source: Tetrahedron [Tetrahedron] 2007 Jul 02; Vol. 63 (27), pp. 6088-6114.

Publication Type: Journal Article

Journal Info: Publisher: Pergamon Press Country of Publication: England NLM ID: 2984170R Publication Model: Print Cited Medium: Print ISSN: 0040-4020 (Print) Linking ISSN: 00404020 NLM ISO Abbreviation: Tetrahedron Subsets: PubMed not MEDLINE

Synthesis of highly substituted N-hydroxyindoles through 1,5-addition of carbon nucleophiles to in situ generated unsaturated nitrones.

Authors: Nicolaou KC Estrada AA Lee SH et al.

Source: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2006 Aug 11; Vol. 45 (32), pp. 5364-8.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 0370543 Publication Model: Print Cited Medium: Print ISSN: 1433-7851 (Print) Linking ISSN: 14337851 NLM ISO Abbreviation: Angew Chem Int Ed Engl Subsets: MEDLINE

Enantioselective partial reduction of 2,5-disubstituted pyrroles via a chiral protonation approach.

Authors: Donohoe TJ Freestone GC Headley CE et al.

Source: Organic letters [Org Lett] 2004 Sep 02; Vol. 6 (18), pp. 3055-8.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print Cited Medium: Print ISSN: 1523-7060 (Print) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

Synthesis of enantiopure dihydropyranones: aldol-based ring expansion of dihydrofurans.

Authors: Donohoe TJ Raoof A Freestone GC et al.

Source: Organic letters [Org Lett] 2002 Sep 05; Vol. 4 (18), pp. 3059-62.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print Cited Medium: Print ISSN: 1523-7060 (Print) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE