Search Results - "Freundlich JS"

Identification of chemical features for improved outer membrane permeation in mycobacteria using machine learning.

Authors: Lepori I Liu Z Evbarunegbe N et al.

Source: Nature microbiology [Nat Microbiol] 2026 Jun 30. Date of Electronic Publication: 2026 Jun 30.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2058-5276 (Electronic) Linking ISSN: 20585276 NLM ISO Abbreviation: Nat Microbiol Subsets: MEDLINE

Study on the phosphorylation of NAD⁺-specific isocitrate dehydrogenase in the pathogenic bacteria Stenotrophomonas maltophilia and Xanthomonas sacchari.

Authors: Tian, Qian Zhang, Yongmei Pan, Chunxu et al.

Source: Journal of Enzyme Inhibition & Medicinal Chemistry. Dec2025, Vol. 40 Issue 1, p1-18. 18p.

Recently developed radiopharmaceuticals for bacterial infection imaging.

Authors: Kahts, Maryke Summers, Beverley Gutta, Aadil et al.

Source: EJNMMI Radiopharmacy & Chemistry. 6/19/2024, Vol. 9 Issue 1, p1-38. 38p.

Proton gradient controls the lateral rearrangement of inner membrane domains in response to membrane fluidizer stress in Mycobacterium smegmatis.

Authors: Prithviraj M Shivangi Freundlich JS et al.

Source: The Journal of biological chemistry [J Biol Chem] 2025 Jul; Vol. 301 (7), pp. 110361. Date of Electronic Publication: 2025 Jun 11.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

The KasA inhibitor JSF-3285 improves the sterilizing activity of bedaquiline-pretomanid-containing regimens in a mouse model of tuberculosis.

Authors: Soni H Tyagi S Mane K et al.

Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2025 Jun 04; Vol. 69 (6), pp. e0013025. Date of Electronic Publication: 2025 Apr 23.

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE

The Goldilocks paradigm: comparing classical machine learning, large language models, and few-shot learning for drug discovery applications.

Authors: Snyder, Scott H. Vignaux, Patricia A. Ozalp, Mustafa Kemal et al.

Source: Communications Chemistry. 6/12/2024, Vol. 7 Issue 1, p1-11. 11p.

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Targeting Mycobacterium tuberculosis response to environmental cues for the development of effective antitubercular drugs.

Authors: Lavin RC Johnson C Ahn YM et al.

Source: PLoS biology [PLoS Biol] 2021 Jul 28; Vol. 19 (7), pp. e3001355. Date of Electronic Publication: 2021 Jul 28 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

Assessment of carbapenems in a mouse model of Mycobacterium tuberculosis infection.

Authors: Jadhav R Gallardo-Macias R Kumar G et al.

Source: PloS one [PLoS One] 2021 May 03; Vol. 16 (5), pp. e0249841. Date of Electronic Publication: 2021 May 03 (Print Publication: 2021).

Publication Type: Journal Article; Research Support, N.I.H., Extramural

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Integrating chemical, genetic, and feasibility assessments for anti-tubercular target validation.

Authors: Schnappinger D Berthel SJ Boshoff HIM et al.

Source: EMBO molecular medicine [EMBO Mol Med] 2026 May; Vol. 18 (5), pp. 1495-1507. Date of Electronic Publication: 2026 Apr 07.

Publication Type: Journal Article; Review

Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE

Mycobacterium tuberculosis KasA as a drug target: Structure-based inhibitor design.

Authors: Rudraraju RS Daher SS Gallardo-Macias R et al.

Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2022 Sep 15; Vol. 12, pp. 1008213. Date of Electronic Publication: 2022 Sep 15 (Print Publication: 2022).

Publication Type: Journal Article; Review; Research Support, N.I.H., Extramural

Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

Computational drug repositioning approach to predict multi-target therapeutics for epilepsy.

Authors: Kumar, Pawan Kumar, Vivek Chauhan, Raveena et al.

Source: Scientific Reports. 12/16/2025, Vol. 15 Issue 1, p1-23. 23p.

Discovery of novel and potent InhA direct inhibitors by ensemble docking-based virtual screening and biological assays.

Authors: Zhang, Qianqian Han, Jianting Zhu, Yongchang et al.

Source: Journal of Computer-Aided Molecular Design; Dec2023, Vol. 37 Issue 12, p695-706, 12p

Machine Learning in Tuberculosis Research: A Global Bibliometric Analysis of Diagnostic, Prognostic, and Drug Discovery Trends.

Authors: Abdelwahab SI Taha MME Mathkour H et al.

Source: Therapeutic innovation & regulatory science [Ther Innov Regul Sci] 2026 Jan; Vol. 60 (1), pp. 161-171. Date of Electronic Publication: 2025 Aug 21.

Publication Type: Journal Article

Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101597411 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2168-4804 (Electronic) Linking ISSN: 21684790 NLM ISO Abbreviation: Ther Innov Regul Sci Subsets: MEDLINE

Insights into enterovirus a-71 antiviral development: from natural sources to synthetic nanoparticles.

Authors: Feferbaum-Leite, Shiraz Santos, Igor Andrade Grosche, Victória Riquena et al.

Source: Archives of Microbiology. Oct2023, Vol. 205 Issue 10, p1-22. 22p.

Label-free assessment of complement-dependent cytotoxicity of therapeutic antibodies via a whole-cell MALDI mass spectrometry bioassay.

Authors: Schmidt, Stefan Geisel, Alexander Enzlein, Thomas et al.

Source: Scientific Reports. 9/13/2024, Vol. 14 Issue 1, p1-11. 11p.

Optimizing tuberculosis treatment efficacy: Comparing the standard regimen with Moxifloxacin-containing regimens.

Authors: Budak, Maral Cicchese, Joseph M. Maiello, Pauline et al.

Source: PLoS Computational Biology. 6/15/2023, Vol. 19 Issue 6, p1-30. 30p. 1 Color Photograph, 1 Diagram, 2 Charts, 6 Graphs.

Convergence model of AI and IoT for virus disease control system.

Authors: Sim, Sungho Cho, Myeongyun

Source: Personal & Ubiquitous Computing; Jun2023, Vol. 27 Issue 3, p1209-1219, 11p

Targeting bioinformatics tools to study the dissemination and spread of antibiotic resistant genes in the environment and clinical settings.

Authors: Singh, Chandra Kant Sodhi, Kushneet Kaur

Source: Critical Reviews in Microbiology. Sep2025, Vol. 51 Issue 5, p860-878. 19p.

A water solubility prediction algorithm based on the StackBoost model.

Authors: Pan, Bin Hou, Xiaoyu Zhang, Mingxin et al.

Source: PLoS ONE. 8/29/2025, Vol. 20 Issue 8, p1-18. 18p.