Search Results - "Fuchs CD"

Crosstalk between CD8+ T cells and systemic bile acid metabolism shapes antiviral immunity and immunopathology.

Authors: Richter FC Keszei Z Viczenczova C et al.

Source: JCI insight [JCI Insight] 2026 Jun 22; Vol. 11 (12). Date of Electronic Publication: 2026 Jun 22 (Print Publication: 2026).

Publication Type: Journal Article

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

Loss of Bile Salt Export Pump (Bsep/Abcb11) Ameliorates Toxin-induced Hepatic Fibrosis via Suppression of Hepatocellular Jun Amino-terminal Kinase Signaling and Hepatic Stellate Cell Activation.

Authors: Fuchs CD Dixon ED Königshofer P et al.

Source: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2026; Vol. 20 (1), pp. 101630. Date of Electronic Publication: 2025 Sep 12.

Publication Type: Journal Article

Journal Info: Publisher: American Gastroenterological Association Country of Publication: United States NLM ID: 101648302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-345X (Electronic) Linking ISSN: 2352345X NLM ISO Abbreviation: Cell Mol Gastroenterol Hepatol Subsets: MEDLINE

Successful AAV8 gene therapy on hepatic ex situ machine perfusion for mitochondrial neurogastrointestinal encephalomyopathy.

Authors: Brevini T Swift L Reynolds H et al.

Source: Journal of hepatology [J Hepatol] 2025 Nov; Vol. 83 (5), pp. 1218-1225. Date of Electronic Publication: 2025 Aug 06.

Publication Type: Case Reports; Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE

Erratum to 'Inhibition of ATGL alleviates MASH via impaired PPARa signalling that favours hydrophilic bile acid composition in mice' [J Hepatol 82 (2025) 658-675].

Authors: Dixon ED Claudel T Nardo AD et al.

Source: Journal of hepatology [J Hepatol] 2025 Nov; Vol. 83 (5), pp. 1236. Date of Electronic Publication: 2025 Aug 30.

Publication Type: Published Erratum

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE; In Process

Bsep/Abcb11 knockout ameliorates Schistosoma mansoni liver pathology by reducing parasite fecundity.

Authors: Macháček T Fuchs CD Winkelmann F et al.

Source: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2023 Nov; Vol. 43 (11), pp. 2469-2478. Date of Electronic Publication: 2023 Aug 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE

Inhibition of ATGL alleviates MASH via impaired PPARα signalling that favours hydrophilic bile acid composition in mice.

Authors: Dixon ED Claudel T Nardo AD et al.

Source: Journal of hepatology [J Hepatol] 2025 Apr; Vol. 82 (4), pp. 658-675. Date of Electronic Publication: 2024 Sep 30.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE

Bile acid metabolism and signalling in liver disease.

Authors: Fuchs CD Simbrunner B Baumgartner M et al.

Source: Journal of hepatology [J Hepatol] 2025 Jan; Vol. 82 (1), pp. 134-153. Date of Electronic Publication: 2024 Sep 28.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE

Non-steroidal FXR agonist cilofexor improves cholestatic liver injury in the Mdr2^-/- mouse model of sclerosing cholangitis.

Authors: Fuchs CD Sroda N Scharnagl H et al.

Source: JHEP reports : innovation in hepatology [JHEP Rep] 2023 Aug 03; Vol. 5 (11), pp. 100874. Date of Electronic Publication: 2023 Aug 03 (Print Publication: 2023).

Publication Type: Journal Article

Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101761237 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5559 (Electronic) Linking ISSN: 25895559 NLM ISO Abbreviation: JHEP Rep Subsets: PubMed not MEDLINE

Absence of Bsep/Abcb11 attenuates MCD diet-induced hepatic steatosis but aggravates inflammation in mice.

Authors: Fuchs CD Krivanec S Steinacher D et al.

Source: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2020 Jun; Vol. 40 (6), pp. 1366-1377. Date of Electronic Publication: 2020 Mar 18.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101160857 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-3231 (Electronic) Linking ISSN: 14783223 NLM ISO Abbreviation: Liver Int Subsets: MEDLINE

Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice.

Authors: Truong JK Li J Li Q et al.

Source: JCI insight [JCI Insight] 2023 Mar 22; Vol. 8 (6). Date of Electronic Publication: 2023 Mar 22.

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2.

Authors: Brevini T Maes M Webb GJ et al.

Corporate Authors: Brevini T Maes M Webb GJ et al.

Source: Nature [Nature] 2023 Mar; Vol. 615 (7950), pp. 134-142. Date of Electronic Publication: 2022 Dec 05.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

GLP-2 Improves Hepatic Inflammation and Fibrosis in Mdr2^-/- Mice Via Activation of NR4a1/Nur77 in Hepatic Stellate Cells and Intestinal FXR Signaling.

Authors: Fuchs CD Claudel T Mlitz V et al.

Source: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2023; Vol. 16 (5), pp. 847-856. Date of Electronic Publication: 2023 Aug 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Gastroenterological Association Country of Publication: United States NLM ID: 101648302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-345X (Electronic) Linking ISSN: 2352345X NLM ISO Abbreviation: Cell Mol Gastroenterol Hepatol Subsets: MEDLINE

Tetrahydroxylated bile acids improve cholestatic liver and bile duct injury in the Mdr2^-/- mouse model of sclerosing cholangitis via immunomodulatory effects.

Authors: Fuchs CD Dixon ED Hendrikx T et al.

Source: Hepatology communications [Hepatol Commun] 2022 Sep; Vol. 6 (9), pp. 2368-2378. Date of Electronic Publication: 2022 Jun 12.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 101695860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2471-254X (Electronic) Linking ISSN: 2471254X NLM ISO Abbreviation: Hepatol Commun Subsets: MEDLINE

FXR controls CHOP expression in steatohepatitis.

Authors: Fuchs CD Claudel T Scharnagl H et al.

Source: FEBS letters [FEBS Lett] 2017 Oct; Vol. 591 (20), pp. 3360-3368. Date of Electronic Publication: 2017 Oct 11.

Publication Type: Journal Article

Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3468 (Electronic) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE

Role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology.

Authors: Fuchs CD Trauner M

Source: Nature reviews. Gastroenterology & hepatology [Nat Rev Gastroenterol Hepatol] 2022 Jul; Vol. 19 (7), pp. 432-450. Date of Electronic Publication: 2022 Feb 14.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101500079 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1759-5053 (Electronic) Linking ISSN: 17595045 NLM ISO Abbreviation: Nat Rev Gastroenterol Hepatol Subsets: MEDLINE

Loss of bile salt export pump aggravates lipopolysaccharide-induced liver injury in mice due to impaired hepatic endotoxin clearance.

Authors: Remetic J Ghallab A Hobloss Z et al.

Source: Hepatology (Baltimore, Md.) [Hepatology] 2022 May; Vol. 75 (5), pp. 1095-1109. Date of Electronic Publication: 2022 Jan 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE

Novel therapeutic targets for cholestatic and fatty liver disease.

Authors: Trauner M Fuchs CD

Source: Gut [Gut] 2022 Jan; Vol. 71 (1), pp. 194-209. Date of Electronic Publication: 2021 Oct 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE

Hepatocyte-specific deletion of adipose triglyceride lipase (adipose triglyceride lipase/patatin-like phospholipase domain containing 2) ameliorates dietary induced steatohepatitis in mice.

Authors: Fuchs CD Radun R Dixon ED et al.

Source: Hepatology (Baltimore, Md.) [Hepatology] 2022 Jan; Vol. 75 (1), pp. 125-139. Date of Electronic Publication: 2021 Dec 04.

Publication Type: Journal Article; Observational Study; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE

24-Norursodeoxycholic acid reshapes immunometabolism in CD8⁺ T cells and alleviates hepatic inflammation.

Authors: Zhu C Boucheron N Müller AC et al.

Source: Journal of hepatology [J Hepatol] 2021 Nov; Vol. 75 (5), pp. 1164-1176. Date of Electronic Publication: 2021 Jul 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE

Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis.

Authors: Reich M Spomer L Klindt C et al.

Source: Journal of hepatology [J Hepatol] 2021 Sep; Vol. 75 (3), pp. 634-646. Date of Electronic Publication: 2021 Apr 17.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE