Search Results - "Futerman AH"

Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease.

Authors: Vitner EB Farfel-Becker T Eilam R et al.

Source: Brain: A Journal of Neurology; Jun2012, Vol. 135 Issue 6, p1724-1735, 12p

Discovery of a potential CERS2 inhibitor: hit compound identification via structure-based virtual screening and molecular dynamics simulations.

Authors: Yu B Mo S Chen Y et al.

Source: Molecular diversity [Mol Divers] 2026 Aug; Vol. 30 (4), pp. 5411-5424. Date of Electronic Publication: 2026 Jan 03.

Publication Type: Journal Article

Journal Info: Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE

It's time to rethink academic innovation: why technology transfer offices can't do it alone.

Authors: Fireman S Futerman AH Sagi I

Source: Nature biotechnology [Nat Biotechnol] 2026 Apr; Vol. 44 (4), pp. 668-669.

Publication Type: Journal Article

Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE; In Process

Why do we study sphingolipids?

Authors: Futerman AH; Department of Biomolecular Sciences, Weizmann Institute of Science, 7610001, Rehovot, Israel. tony.futerman@weizmann.ac.il.

Source: Pflugers Archiv : European journal of physiology [Pflugers Arch] 2024 Dec; Vol. 476 (12), pp. 1781-1788. Date of Electronic Publication: 2024 Sep 19.

Publication Type: Journal Article; Review

Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 0154720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2013 (Electronic) Linking ISSN: 00316768 NLM ISO Abbreviation: Pflugers Arch Subsets: MEDLINE

Nucleolin perturbation alters membrane lipid homeostasis.

Authors: Zahavi EE Rishal I Oses-Prieto JA et al.

Source: Molecular omics [Mol Omics] 2025 Dec 01; Vol. 21 (6), pp. 723-735. Date of Electronic Publication: 2025 Dec 01.

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101713384 Publication Model: Electronic Cited Medium: Internet ISSN: 2515-4184 (Electronic) Linking ISSN: 25154184 NLM ISO Abbreviation: Mol Omics Subsets: MEDLINE

Fine-tuned protein-lipid interactions in biological membranes: exploration and implications of the ORMDL-ceramide negative feedback loop in the endoplasmic reticulum.

Authors: Dingjan T Futerman AH

Source: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2024 Aug 07; Vol. 12, pp. 1457209. Date of Electronic Publication: 2024 Aug 07 (Print Publication: 2024).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE

Large-scale proteomics analysis of five brain regions from Parkinson's disease patients with a GBA1 mutation.

Authors: Blumenreich S Nehushtan T Kupervaser M et al.

Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2024 Feb 08; Vol. 10 (1), pp. 33. Date of Electronic Publication: 2024 Feb 08.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE

Proteomics analysis of the brain from a Gaucher disease mouse identifies pathological pathways including a possible role for transglutaminase 1.

Authors: Blumenreich S Ben-Yashar DP Shalit T et al.

Source: Journal of neurochemistry [J Neurochem] 2024 Jan; Vol. 168 (1), pp. 52-65. Date of Electronic Publication: 2023 Dec 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley on behalf of the International Society for Neurochemistry Country of Publication: England NLM ID: 2985190R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-4159 (Electronic) Linking ISSN: 00223042 NLM ISO Abbreviation: J Neurochem Subsets: MEDLINE

Ultrafast Measurement of Circulating Ceramides in Human Cohorts.

Authors: Tham WK Chang JK Teo GS et al.

Source: Analytical chemistry [Anal Chem] 2025 Jul 08; Vol. 97 (26), pp. 13789-13798. Date of Electronic Publication: 2025 Jun 25.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE

Deep sphingolipidomic and metabolomic analyses of ceramide synthase 2 null mice reveal complex pathway-specific effects.

Authors: Oh J Muralidharan S Zhao Q et al.

Source: Journal of lipid research [J Lipid Res] 2025 Jul; Vol. 66 (7), pp. 100832. Date of Electronic Publication: 2025 May 29.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0376606 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-7262 (Electronic) Linking ISSN: 00222275 NLM ISO Abbreviation: J Lipid Res Subsets: MEDLINE

Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.

Authors: Pokorna S Khersonsky O Lipsh-Sokolik R et al.

Source: The FEBS journal [FEBS J] 2023 Jul; Vol. 290 (13), pp. 3383-3399. Date of Electronic Publication: 2023 Mar 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE

Computational design and molecular dynamics simulations suggest the mode of substrate binding in ceramide synthases.

Authors: Zelnik ID Mestre B Weinstein JJ et al.

Source: Nature communications [Nat Commun] 2023 Apr 22; Vol. 14 (1), pp. 2330. Date of Electronic Publication: 2023 Apr 22.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Reduced circulating sphingolipids and CERS2 activity are linked to T2D risk and impaired insulin secretion.

Authors: Khan SR Ye WW Van JAD et al.

Source: Science advances [Sci Adv] 2025 Jan 10; Vol. 11 (2), pp. eadr1725. Date of Electronic Publication: 2025 Jan 10.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

An anomalous abundance of tryptophan residues in ceramide synthases based on analysis of all membrane proteins in the Swiss-Prot database.

Authors: Mestre B Zelnik ID Izrailov S et al.

Source: The Journal of biological chemistry [J Biol Chem] 2025 Jan; Vol. 301 (1), pp. 108053. Date of Electronic Publication: 2024 Dec 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

The sphingolipid anteome: implications for evolution of the sphingolipid metabolic pathway.

Authors: Santos TCB Dingjan T Futerman AH

Source: FEBS letters [FEBS Lett] 2022 Sep; Vol. 596 (18), pp. 2345-2363. Date of Electronic Publication: 2022 Aug 04.

Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't

Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 0155157 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3468 (Electronic) Linking ISSN: 00145793 NLM ISO Abbreviation: FEBS Lett Subsets: MEDLINE

Elevation of gangliosides in four brain regions from Parkinson's disease patients with a GBA mutation.

Authors: Blumenreich S Nehushtan T Barav OB et al.

Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2022 Aug 06; Vol. 8 (1), pp. 99. Date of Electronic Publication: 2022 Aug 06.

Publication Type: Journal Article

Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE

Generation of a ceramide synthase 6 mouse lacking the DDRSDIE C-terminal motif.

Authors: Kim J Pewzner-Jung Y Joseph T et al.

Source: PloS one [PLoS One] 2022 Jul 18; Vol. 17 (7), pp. e0271675. Date of Electronic Publication: 2022 Jul 18 (Print Publication: 2022).

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Efficacy of an AAV vector encoding a thermostable form of glucocerebrosidase in alleviating symptoms in a Gaucher disease mouse model.

Authors: Milenkovic I Blumenreich S Hochfelder A et al.

Source: Gene therapy [Gene Ther] 2024 Sep; Vol. 31 (9-10), pp. 439-444. Date of Electronic Publication: 2024 Aug 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5462 (Electronic) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE

How has the evolution of our understanding of the compartmentalization of sphingolipid biosynthesis over the past 30 years altered our view of the evolution of the pathway?

Authors: Biran A Dingjan T Futerman AH

Source: Current topics in membranes [Curr Top Membr] 2024 Jun 24. Date of Electronic Publication: 2024 Jun 24.

Publication Type: Journal Article

Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9212591 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1063-5823 (Print) Linking ISSN: 10635823 NLM ISO Abbreviation: Curr Top Membr Subsets: MEDLINE

The Sphinx and the egg: Evolutionary enigmas of the (glyco)sphingolipid biosynthetic pathway.

Authors: Biran A Santos TCB Dingjan T et al.

Source: Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2024 Apr; Vol. 1869 (3), pp. 159462. Date of Electronic Publication: 2024 Feb 01.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731727 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2618 (Electronic) Linking ISSN: 13881981 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Biol Lipids Subsets: MEDLINE