Search Results - "Gabe MBN"

Global glucagon-like peptide-2 receptor activation linked to increased obesity risk in the UK Biobank.

Authors: Gerlach PA Gadgaard S Madsen JS et al.

Source: Metabolism: clinical and experimental [Metabolism] 2026 Apr; Vol. 177, pp. 156489. Date of Electronic Publication: 2026 Jan 08.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0375267 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8600 (Electronic) Linking ISSN: 00260495 NLM ISO Abbreviation: Metabolism Subsets: MEDLINE

Cagrilintide is not associated with clinically relevant QTc prolongation: A thorough QT study in healthy participants.

Authors: Gabe MBN Fuhr R Sinn A et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Dec; Vol. 26 (12), pp. 5805-5811. Date of Electronic Publication: 2024 Sep 16.

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Effect of oral semaglutide on energy intake, appetite, control of eating and gastric emptying in adults living with obesity: A randomized controlled trial.

Authors: Gabe MBN Breitschaft A Knop FK et al.

Source: Diabetes, obesity & metabolism [Diabetes Obes Metab] 2024 Oct; Vol. 26 (10), pp. 4480-4489. Date of Electronic Publication: 2024 Jul 31.

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883645 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1463-1326 (Electronic) Linking ISSN: 14628902 NLM ISO Abbreviation: Diabetes Obes Metab Subsets: MEDLINE

Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice.

Authors: Gabe MBN von Voss L Hunt JE et al.

Source: British journal of pharmacology [Br J Pharmacol] 2023 Jul; Vol. 180 (13), pp. 1674-1689. Date of Electronic Publication: 2023 Feb 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Glucose-dependent insulinotropic polypeptide receptor antagonist treatment causes a reduction in weight gain in ovariectomised high fat diet-fed mice.

Authors: Boer GA Hunt JE Gabe MBN et al.

Source: British journal of pharmacology [Br J Pharmacol] 2022 Sep; Vol. 179 (18), pp. 4486-4499. Date of Electronic Publication: 2022 Jul 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction.

Authors: Gabe MBN Gasbjerg LS Gadgaard S et al.

Source: British journal of pharmacology [Br J Pharmacol] 2022 Sep; Vol. 179 (18), pp. 4473-4485. Date of Electronic Publication: 2022 Jun 08.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Novel agonist and antagonist radioligands for the GLP-2 receptor. Useful tools for studies of basic GLP-2 receptor pharmacology.

Authors: Gadgaard S van der Velden WJC Schiellerup SP et al.

Source: British journal of pharmacology [Br J Pharmacol] 2022 May; Vol. 179 (9), pp. 1998-2015. Date of Electronic Publication: 2022 Jan 11.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE

Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long-term impairment of the GIP system.

Authors: Gabe MBN van der Velden WJC Gadgaard S et al.

Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2020 Jun; Vol. 126 Suppl 6, pp. 122-132. Date of Electronic Publication: 2019 Aug 19.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843 (Electronic) Linking ISSN: 17427835 NLM ISO Abbreviation: Basic Clin Pharmacol Toxicol Subsets: MEDLINE

Paracrine crosstalk between intestinal L- and D-cells controls secretion of glucagon-like peptide-1 in mice.

Authors: Jepsen SL Grunddal KV Wewer Albrechtsen NJ et al.

Source: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2019 Dec 01; Vol. 317 (6), pp. E1081-E1093. Date of Electronic Publication: 2019 Sep 10.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1555 (Electronic) Linking ISSN: 01931849 NLM ISO Abbreviation: Am J Physiol Endocrinol Metab Subsets: MEDLINE

Separate and Combined Glucometabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide 1 in Healthy Individuals.

Authors: Gasbjerg LS Helsted MM Hartmann B et al.

Source: Diabetes [Diabetes] 2019 May; Vol. 68 (5), pp. 906-917. Date of Electronic Publication: 2019 Jan 09.

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE

The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon.

Authors: Christiansen CB Gabe MBN Svendsen B et al.

Source: American journal of physiology. Gastrointestinal and liver physiology [Am J Physiol Gastrointest Liver Physiol] 2018 Jul 01; Vol. 315 (1), pp. G53-G65. Date of Electronic Publication: 2018 Mar 01.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1547 (Electronic) Linking ISSN: 01931857 NLM ISO Abbreviation: Am J Physiol Gastrointest Liver Physiol Subsets: MEDLINE

GIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study.

Authors: Gasbjerg LS Christensen MB Hartmann B et al.

Source: Diabetologia [Diabetologia] 2018 Feb; Vol. 61 (2), pp. 413-423. Date of Electronic Publication: 2017 Sep 25.

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE

GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment.

Authors: Gabe MBN Skov-Jeppesen K Gasbjerg LS et al.

Source: Pharmacological research [Pharmacol Res] 2022 Feb; Vol. 176, pp. 106058. Date of Electronic Publication: 2022 Jan 04.

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1186 (Electronic) Linking ISSN: 10436618 NLM ISO Abbreviation: Pharmacol Res Subsets: MEDLINE

Molecular interactions of full-length and truncated GIP peptides with the GIP receptor - A comprehensive review.

Authors: Gabe MBN van der Velden WJC Smit FX et al.

Source: Peptides [Peptides] 2020 Mar; Vol. 125, pp. 170224. Date of Electronic Publication: 2019 Dec 03.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 8008690 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5169 (Electronic) Linking ISSN: 01969781 NLM ISO Abbreviation: Peptides Subsets: MEDLINE

GLP-2 and GIP exert separate effects on bone turnover: A randomized, placebo-controlled, crossover study in healthy young men.

Authors: Skov-Jeppesen K Svane MS Martinussen C et al.

Source: Bone [Bone] 2019 Aug; Vol. 125, pp. 178-185. Date of Electronic Publication: 2019 May 15.

Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8504048 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2763 (Electronic) Linking ISSN: 18732763 NLM ISO Abbreviation: Bone Subsets: MEDLINE

Neuromedin U Does Not Act as a Decretin in Rats.

Authors: Kuhre RE Christiansen CB Ghiasi SM et al.

Source: Cell metabolism [Cell Metab] 2019 Mar 05; Vol. 29 (3), pp. 719-726.e5. Date of Electronic Publication: 2018 Nov 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE

Insulin Secretion Depends on Intra-islet Glucagon Signaling.

Authors: Svendsen B Larsen O Gabe MBN et al.

Source: Cell reports [Cell Rep] 2018 Oct 30; Vol. 25 (5), pp. 1127-1134.e2.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

Human GIP(3-30)NH2 inhibits G protein-dependent as well as G protein-independent signaling and is selective for the GIP receptor with high-affinity binding to primate but not rodent GIP receptors.

Authors: Gabe MBN Sparre-Ulrich AH Pedersen MF et al.

Source: Biochemical pharmacology [Biochem Pharmacol] 2018 Apr; Vol. 150, pp. 97-107. Date of Electronic Publication: 2018 Feb 03.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE

Oxyntomodulin: Actions and role in diabetes.

Authors: Holst JJ Albrechtsen NJW Gabe MBN et al.

Source: Peptides [Peptides] 2018 Feb; Vol. 100, pp. 48-53.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 8008690 Publication Model: Print Cited Medium: Internet ISSN: 1873-5169 (Electronic) Linking ISSN: 01969781 NLM ISO Abbreviation: Peptides Subsets: MEDLINE

Glucose-dependent insulinotropic polypeptide (GIP) receptor antagonists as anti-diabetic agents.

Authors: Gasbjerg LS Gabe MBN Hartmann B et al.

Source: Peptides [Peptides] 2018 Feb; Vol. 100, pp. 173-181.

Publication Type: Journal Article; Review

Journal Info: Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 8008690 Publication Model: Print Cited Medium: Internet ISSN: 1873-5169 (Electronic) Linking ISSN: 01969781 NLM ISO Abbreviation: Peptides Subsets: MEDLINE