Search Results - "Gentry PR"

Cryo-EM reveals an extrahelical allosteric binding site at the M5 mAChR.

Authors: Burger WAC Mobbs JI Rana B et al.

Source: Nature communications [Nat Commun] 2025 Jul 31; Vol. 16 (1), pp. 7046. Date of Electronic Publication: 2025 Jul 31.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Evaluation of a high-throughput in-vitro-to-in-vivo extrapolation (IVIVE) workflow for the prioritization of potential developmental toxicity of chemicals.

Authors: Linakis MW Clewell RA Campbell J et al.

Source: ALTEX [ALTEX] 2025; Vol. 42 (4), pp. 610-624. Date of Electronic Publication: 2025 May 28.

Publication Type: Journal Article

Journal Info: Publisher: Spektrum Akademischer Verlag Country of Publication: Germany NLM ID: 100953980 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1868-8551 (Electronic) Linking ISSN: 1868596X NLM ISO Abbreviation: ALTEX Subsets: MEDLINE

A framework for integrating evidence to assess hazards and risk.

Authors: Sulsky SI Greene T Gentry PR

Source: Critical reviews in toxicology [Crit Rev Toxicol] 2024 May; Vol. 54 (5), pp. 315-329. Date of Electronic Publication: 2024 May 29.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8914275 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1547-6898 (Electronic) Linking ISSN: 10408444 NLM ISO Abbreviation: Crit Rev Toxicol Subsets: MEDLINE

Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene.

Authors: Campbell JL Jr Clewell HJ 3rd Van Landingham C et al.

Source: Frontiers in pharmacology [Front Pharmacol] 2023 Aug 17; Vol. 14, pp. 1223808. Date of Electronic Publication: 2023 Aug 17 (Print Publication: 2023).

Publication Type: Journal Article

Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE

Updating the biologically based dose-response model for the nasal carcinogenicity of inhaled formaldehyde in the F344 rat.

Authors: Conolly RB Schroeter J Kimbell JS et al.

Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2023 May 12; Vol. 193 (1), pp. 1-17.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

Incorporation of rapid association/dissociation processes in tissues into the monkey and human physiologically based pharmacokinetic models for manganese.

Authors: Campbell JL Clewell HJ Van Landingham C et al.

Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2023 Feb 17; Vol. 191 (2), pp. 212-226.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

Relative contributions of endogenous and exogenous formaldehyde to formation of deoxyguanosine monoadducts and DNA-protein crosslink adducts of DNA in rat nasal mucosa.

Authors: Conolly RB Campbell JL Clewell HJ et al.

Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2023 Jan 31; Vol. 191 (1), pp. 15-24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

Cryo-EM reveals a new allosteric binding site at the M5 mAChR.

Authors: Burger WAC Mobbs JI Rana B et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Feb 08. Date of Electronic Publication: 2025 Feb 08.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Delineation of the GPR15 receptor-mediated Gα protein signalling profile in recombinant mammalian cells.

Authors: Deng Y Moo EV Almería CVP et al.

Source: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2022 Aug; Vol. 131 (2), pp. 104-113. Date of Electronic Publication: 2022 Jun 01.

Publication Type: Journal Article

Journal Info: Publisher: Blackwell Country of Publication: England NLM ID: 101208422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-7843 (Electronic) Linking ISSN: 17427835 NLM ISO Abbreviation: Basic Clin Pharmacol Toxicol Subsets: MEDLINE

A Kinetic Analysis of DNA-Deoxy Guanine Adducts in the Nasal Epithelium Produced by Inhaled Formaldehyde in Rats-Assessing Contributions to Adduct Production From Both Endogenous and Exogenous Sources of Formaldehyde.

Authors: Campbell JL Jr Gentry PR Clewell Iii HJ et al.

Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2020 Oct 01; Vol. 177 (2), pp. 325-333.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

Response to "letter concerning: Clewell (2019) incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene." (UIHT-2020-0053).

Authors: Clewell HJ 3rd Campbell JL Van Landingham C et al.

Source: Inhalation toxicology [Inhal Toxicol] 2020 Aug; Vol. 32 (9-10), pp. 369-371. Date of Electronic Publication: 2020 Sep 08.

Publication Type: Letter; Comment

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8910739 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-7691 (Electronic) Linking ISSN: 08958378 NLM ISO Abbreviation: Inhal Toxicol Subsets: MEDLINE

Extended Analysis and Evidence Integration of Chloroprene as a Human Carcinogen.

Authors: Sax SN Gentry PR Van Landingham C et al.

Source: Risk analysis : an official publication of the Society for Risk Analysis [Risk Anal] 2020 Feb; Vol. 40 (2), pp. 294-318. Date of Electronic Publication: 2019 Sep 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Blackwell Publishers Country of Publication: United States NLM ID: 8109978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-6924 (Electronic) Linking ISSN: 02724332 NLM ISO Abbreviation: Risk Anal Subsets: MEDLINE

Incorporation of in vitro metabolism data and physiologically based pharmacokinetic modeling in a risk assessment for chloroprene.

Authors: Clewell HJ 3rd Campbell JL Van Landingham C et al.

Source: Inhalation toxicology [Inhal Toxicol] 2019 Nov - Dec; Vol. 31 (13-14), pp. 468-483. Date of Electronic Publication: 2020 Jan 28.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8910739 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-7691 (Electronic) Linking ISSN: 08958378 NLM ISO Abbreviation: Inhal Toxicol Subsets: MEDLINE

Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139.

Authors: Pallareti L Rath TF Trapkov B et al.

Source: European journal of pharmacology [Eur J Pharmacol] 2023 Mar 15; Vol. 943, pp. 175553. Date of Electronic Publication: 2023 Feb 02.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

Peak Exposures in Epidemiologic Studies and Cancer Risks: Considerations for Regulatory Risk Assessment.

Authors: Checkoway H Lees PSJ Dell LD et al.

Source: Risk analysis : an official publication of the Society for Risk Analysis [Risk Anal] 2019 Jul; Vol. 39 (7), pp. 1441-1464. Date of Electronic Publication: 2019 Mar 29.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Blackwell Publishers Country of Publication: United States NLM ID: 8109978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1539-6924 (Electronic) Linking ISSN: 02724332 NLM ISO Abbreviation: Risk Anal Subsets: MEDLINE

Dose-response for assessing the cancer risk of inorganic arsenic in drinking water: the scientific basis for use of a threshold approach.

Authors: Tsuji JS Chang ET Gentry PR et al.

Source: Critical reviews in toxicology [Crit Rev Toxicol] 2019 Jan; Vol. 49 (1), pp. 36-84. Date of Electronic Publication: 2019 Apr 01.

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8914275 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1547-6898 (Electronic) Linking ISSN: 10408444 NLM ISO Abbreviation: Crit Rev Toxicol Subsets: MEDLINE

Response to Dr. Bernard D. Goldstein's Letter to the Editor.

Authors: Mundt KA Gallagher AE Dell LD et al.

Source: Critical reviews in toxicology [Crit Rev Toxicol] 2018 May; Vol. 48 (5), pp. 341-343. Date of Electronic Publication: 2018 Feb 20.

Publication Type: Letter; Research Support, Non-U.S. Gov't; Comment

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8914275 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1547-6898 (Electronic) Linking ISSN: 10408444 NLM ISO Abbreviation: Crit Rev Toxicol Subsets: MEDLINE

Molecular insights into ligand recognition and G protein coupling of the neuromodulatory orphan receptor GPR139.

Authors: Zhou Y Daver H Trapkov B et al.

Source: Cell research [Cell Res] 2022 Feb; Vol. 32 (2), pp. 210-213. Date of Electronic Publication: 2021 Dec 17.

Publication Type: Letter; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9425763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1748-7838 (Electronic) Linking ISSN: 10010602 NLM ISO Abbreviation: Cell Res Subsets: MEDLINE

Time-dependent genomic response in primary human uroepithelial cells exposed to arsenite for up to 60 days.

Authors: Efremenko A Balbuena P Clewell RA et al.

Source: Toxicology [Toxicology] 2021 Sep; Vol. 461, pp. 152893. Date of Electronic Publication: 2021 Aug 20.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3185 (Electronic) Linking ISSN: 0300483X NLM ISO Abbreviation: Toxicology Subsets: MEDLINE

Does occupational exposure to formaldehyde cause hematotoxicity and leukemia-specific chromosome changes in cultured myeloid progenitor cells?

Authors: Mundt KA Gallagher AE Dell LD et al.

Source: Critical reviews in toxicology [Crit Rev Toxicol] 2017 Aug; Vol. 47 (7), pp. 592-602. Date of Electronic Publication: 2017 May 02.

Publication Type: Journal Article; Review

Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8914275 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1547-6898 (Electronic) Linking ISSN: 10408444 NLM ISO Abbreviation: Crit Rev Toxicol Subsets: MEDLINE