Search Results - "Gleeson MP"

A controlled trial of exercise rehabilitation after heart transplantation.

Authors: Kobashigawa JA Leaf DA Lee N et al.

Source: New England Journal of Medicine. 01/28/99, Vol. 340 Issue 4, p272-277. 6p.

Selective pulmonary vasorelaxant effects of an N²,N⁴-diaminoquinazoline PDE5 inhibitor involving endothelial signaling and ion channel modulation.

Authors: Chatturong U Meebangsue T Guntur G et al.

Source: European journal of pharmacology [Eur J Pharmacol] 2026 Jul 17; Vol. 1030, pp. 179154. Date of Electronic Publication: 2026 Jul 17.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

More than an attachment module: covalent inhibitor warheads influence BTK dynamics and function.

Authors: Joseph RE Britton RG Lin DY et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 08. Date of Electronic Publication: 2026 May 08.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Computationally guided design of N⁴-(2-methyl-2H-indazol-6-yl)-N²-phenylpyrimidine-2,4-diamine inhibitors of EGFR kinase targeting Cys797.

Authors: Konsue A Gleeson D Choowongkomon K et al.

Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2026 Mar; Vol. 134, pp. 118544. Date of Electronic Publication: 2026 Jan 02.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

Comparison of feline and human immunodeficiency virus reverse transcriptase enzymes through chemical screening and computational analysis.

Authors: Thammajong P Aiebchun T Boonyarattanakalin K et al.

Source: Chemical biology & drug design [Chem Biol Drug Des] 2024 May; Vol. 103 (5), pp. e14530.

Publication Type: Journal Article; Comparative Study; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print Cited Medium: Internet ISSN: 1747-0285 (Electronic) Linking ISSN: 17470277 NLM ISO Abbreviation: Chem Biol Drug Des Subsets: MEDLINE

Synthesis of Functionalized Benzo[h]Quinolines via Base-Catalyzed 1,4-Addition/Intramolecular Annulation Cascade.

Authors: Disadee W Gleeson MP Ruchirawat S

Source: Chemistry, an Asian journal [Chem Asian J] 2025 Sep; Vol. 20 (18), pp. e00587. Date of Electronic Publication: 2025 Jun 23.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101294643 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1861-471X (Electronic) Linking ISSN: 1861471X NLM ISO Abbreviation: Chem Asian J Subsets: MEDLINE; PubMed not MEDLINE

Computationally guided optimization of the antimalarial activity and physicochemical properties of 2,4-diaminopyrimidines.

Authors: Guntur G Gleeson D Anderson M et al.

Source: RSC medicinal chemistry [RSC Med Chem] 2025 Aug 20. Date of Electronic Publication: 2025 Aug 20.

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem

Probing the Effect of Protein and Inhibitor Conformational Flexibility on the Reaction of Rocelitinib-Like Covalent Inhibitors of Epidermal Growth Factor Receptor. A Quantum Mechanics/Molecular Mechanics Study.

Authors: Kaewkham O Gleeson D Fukasem P et al.

Source: Journal of chemical information and modeling [J Chem Inf Model] 2025 Apr 14; Vol. 65 (7), pp. 3555-3567. Date of Electronic Publication: 2025 Mar 18.

Publication Type: Journal Article

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101230060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-960X (Electronic) Linking ISSN: 15499596 NLM ISO Abbreviation: J Chem Inf Model Subsets: MEDLINE

Estimation of the Skin Sensitization Potential of Chemicals of the Acyl Domain Using DFT-Based Calculations.

Authors: Limluan P Gleeson MP Gleeson D

Source: Chemical research in toxicology [Chem Res Toxicol] 2024 Nov 18; Vol. 37 (11), pp. 1876-1883. Date of Electronic Publication: 2024 Oct 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 8807448 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5010 (Electronic) Linking ISSN: 0893228X NLM ISO Abbreviation: Chem Res Toxicol Subsets: MEDLINE

Design, preparation and biological evaluation of new Rociletinib-inspired analogs as irreversible EGFR inhibitors to treat non-small-cell-lung cancer.

Authors: Konsue A Lamtha T Gleeson D et al.

Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2024 Nov 01; Vol. 113, pp. 117906. Date of Electronic Publication: 2024 Sep 07.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

The new quinazoline derivative (N²-methyl-N⁴-[(thiophen-2-yl)methyl]quinazoline-2,4-diamine) vasodilates isolated mesenteric arteries through endothelium-independent mechanisms and has acute hypotensive effects in Wistar rats.

Authors: Chatturong U Chootip K Martin H et al.

Source: European journal of pharmacology [Eur J Pharmacol] 2023 Aug 15; Vol. 953, pp. 175829. Date of Electronic Publication: 2023 Jun 10.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

Investigation of Factors Affecting the Performance of in silico Volume Distribution QSAR Models for Human, Rat, Mouse, Dog & Monkey.

Authors: Simeon S Montanari D Gleeson MP

Source: Molecular informatics [Mol Inform] 2019 Oct; Vol. 38 (10), pp. e1900059. Date of Electronic Publication: 2019 Aug 02.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Wiley-VCH Verlag Country of Publication: Germany NLM ID: 101529315 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1868-1751 (Electronic) Linking ISSN: 18681743 NLM ISO Abbreviation: Mol Inform Subsets: MEDLINE

Insights into the EGFR SAR of N-phenylquinazolin-4-amine-derivatives using quantum mechanical pairwise-interaction energies.

Authors: Simeon S Jongkon N Chotpatiwetchkul W et al.

Source: Journal of computer-aided molecular design [J Comput Aided Mol Des] 2019 Aug; Vol. 33 (8), pp. 745-757. Date of Electronic Publication: 2019 Sep 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 8710425 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4951 (Electronic) Linking ISSN: 0920654X NLM ISO Abbreviation: J Comput Aided Mol Des Subsets: MEDLINE

Computational investigation of the radical-mediated mechanism of formation of difluoro methyl oxindoles: Elucidation of the reaction selectivity and yields.

Authors: Somnarin T Krawmanee P Gleeson MP et al.

Source: Journal of computational chemistry [J Comput Chem] 2023 Feb 15; Vol. 44 (5), pp. 670-676. Date of Electronic Publication: 2022 Nov 18.

Publication Type: Journal Article

Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 9878362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-987X (Electronic) Linking ISSN: 01928651 NLM ISO Abbreviation: J Comput Chem Subsets: MEDLINE; PubMed not MEDLINE

In silico identification and in vitro validation of nogalamycin N-oxide (NSC116555) as a potent anticancer compound against non-small-cell lung cancer cells.

Authors: Obounchoey P Tabtimmai L Suphakun P et al.

Source: Journal of cellular biochemistry [J Cell Biochem] 2019 Mar; Vol. 120 (3), pp. 3353-3361. Date of Electronic Publication: 2018 Oct 15.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Validation Study

Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8205768 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4644 (Electronic) Linking ISSN: 07302312 NLM ISO Abbreviation: J Cell Biochem Subsets: MEDLINE

Elucidation of Vasodilation Response and Structure Activity Relationships of N²,N⁴-Disubstituted Quinazoline 2,4-Diamines in a Rat Pulmonary Artery Model.

Authors: Paracha TU Pobsuk N Salaloy N et al.

Source: Molecules (Basel, Switzerland) [Molecules] 2019 Jan 14; Vol. 24 (2). Date of Electronic Publication: 2019 Jan 14.

Publication Type: Journal Article

Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

Quinazoline-based human phosphodiesterase 5 inhibitors exhibited a selective vasorelaxant effect on rat isolated pulmonary arteries involving NO-sGC-cGMP pathway and calcium inhibitory effects.

Authors: Chatturong U Martin H Totoson P et al.

Source: Vascular pharmacology [Vascul Pharmacol] 2022 Dec; Vol. 147, pp. 107111. Date of Electronic Publication: 2022 Sep 24.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 101130615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3649 (Electronic) Linking ISSN: 15371891 NLM ISO Abbreviation: Vascul Pharmacol Subsets: MEDLINE

Preparation, biological evaluation and QSAR analysis of urea substituted 2,4-diamino-pyrimidine anti-malarials.

Authors: Toviwek B Riley J Mutter N et al.

Source: RSC medicinal chemistry [RSC Med Chem] 2022 Oct 20; Vol. 13 (12), pp. 1587-1604. Date of Electronic Publication: 2022 Oct 20 (Print Publication: 2022).

Publication Type: Journal Article

Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101759460 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8682 (Electronic) Linking ISSN: 26328682 NLM ISO Abbreviation: RSC Med Chem Subsets: PubMed not MEDLINE

Design, synthesis, and evaluation of the anticancer activity of 2-amino-aryl-7-aryl-benzoxazole compounds.

Authors: Khajondetchairit P Phuangsawai O Suphakun P et al.

Source: Chemical biology & drug design [Chem Biol Drug Des] 2017 Nov; Vol. 90 (5), pp. 987-994. Date of Electronic Publication: 2017 Jun 28.

Publication Type: Journal Article

Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-0285 (Electronic) Linking ISSN: 17470277 NLM ISO Abbreviation: Chem Biol Drug Des Subsets: MEDLINE

Preparation, biological & cheminformatics-based assessment of N²,N⁴-diphenylpyrimidine-2,4-diamine as potential Kinase-targeted antimalarials.

Authors: Toviwek B Phuangsawai O Konsue A et al.

Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2021 Sep 15; Vol. 46, pp. 116348. Date of Electronic Publication: 2021 Aug 08.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE