Search Results - "Gozdecka M"

BCOR mutations define a therapeutic vulnerability to DHODH Inhibition in acute myeloid leukemia.

Authors: Robert F Badja C Boushaki S et al.

Source: Annals of hematology [Ann Hematol] 2026 Jan 19; Vol. 105 (1), pp. 32. Date of Electronic Publication: 2026 Jan 19.

Publication Type: Journal Article

Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 9107334 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-0584 (Electronic) Linking ISSN: 09395555 NLM ISO Abbreviation: Ann Hematol Subsets: MEDLINE

Statin Use and Genetically Predicted HMG-CoA Reductase Inhibition in Relation to Clonal Hematopoiesis.

Authors: Carter PR Gozdecka M Wen S et al.

Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 Jul 13. Date of Electronic Publication: 2026 Jul 13.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

Polθ activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemia.

Authors: Le BV Vekariya U Toma MM et al.

Source: Cell reports. Medicine [Cell Rep Med] 2026 Mar 17; Vol. 7 (3), pp. 102687.

Publication Type: Journal Article

Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE

Posttranscriptional depletion of ribosome biogenesis factors engenders therapeutic vulnerabilities in NPM1-mutant AML.

Authors: Damaskou A Wilson R Gozdecka M et al.

Source: Blood [Blood] 2025 Sep 04; Vol. 146 (10), pp. 1239-1252.

Publication Type: Journal Article

Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE

Telomere attrition becomes an instrument for clonal selection in aging hematopoiesis and leukemogenesis.

Authors: McLoughlin MA Cheloor Kovilakam S Dunn WG et al.

Source: Nature genetics [Nat Genet] 2025 Sep; Vol. 57 (9), pp. 2215-2225. Date of Electronic Publication: 2025 Aug 28.

Publication Type: Journal Article

Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis.

Authors: Gozdecka M Dudek M Wen S et al.

Source: Nature [Nature] 2025 Jun; Vol. 642 (8067), pp. 431-441. Date of Electronic Publication: 2025 Apr 16.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

DNA polymerase theta-mediated DNA repair is a functional dependency and therapeutic vulnerability in DNMT3A deficient leukemia cells.

Authors: Le BV Vekariya U Toma MM et al.

Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 19. Date of Electronic Publication: 2024 Sep 19.

Publication Type: Journal Article; Preprint

Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes.

Authors: Isobe T Kucinski I Barile M et al.

Source: Cell genomics [Cell Genom] 2023 Oct 27; Vol. 3 (12), pp. 100426. Date of Electronic Publication: 2023 Oct 27 (Print Publication: 2023).

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 9918284260106676 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-979X (Electronic) Linking ISSN: 2666979X NLM ISO Abbreviation: Cell Genom Subsets: MEDLINE; PubMed not MEDLINE

Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages.

Authors: Sturgess K Yankova E Vijayabaskar MS et al.

Source: Leukemia [Leukemia] 2023 Oct; Vol. 37 (10), pp. 2133-2137. Date of Electronic Publication: 2023 Jul 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.

Authors: Tzelepis K De Braekeleer E Aspris D et al.

Source: Nature communications [Nat Commun] 2018 Dec 19; Vol. 9 (1), pp. 5378. Date of Electronic Publication: 2018 Dec 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Transcriptional variability accelerates preleukemia by cell diversification and perturbation of protein synthesis.

Authors: Gupta S Dovey OM Domingues AF et al.

Source: Science advances [Sci Adv] 2022 Aug 05; Vol. 8 (31), pp. eabn4886. Date of Electronic Publication: 2022 Aug 03.

Publication Type: Journal Article

Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

Publisher Correction: UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.

Authors: Gozdecka M Meduri E Mazan M et al.

Source: Nature genetics [Nat Genet] 2022 Jul; Vol. 54 (7), pp. 1062.

Publication Type: Published Erratum

Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE; PubMed not MEDLINE

Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression.

Authors: Yun H Narayan N Vohra S et al.

Source: Nature genetics [Nat Genet] 2021 Oct; Vol. 53 (10), pp. 1443-1455. Date of Electronic Publication: 2021 Sep 23.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

SETBP1 overexpression acts in the place of class-defining mutations to drive FLT3-ITD-mutant AML.

Authors: Pacharne S Dovey OM Cooper JL et al.

Source: Blood advances [Blood Adv] 2021 May 11; Vol. 5 (9), pp. 2412-2425.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE

Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.

Authors: Yankova E Blackaby W Albertella M et al.

Source: Nature [Nature] 2021 May; Vol. 593 (7860), pp. 597-601. Date of Electronic Publication: 2021 Apr 26.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements.

Authors: Au YZ Gu M De Braekeleer E et al.

Source: Leukemia [Leukemia] 2021 Apr; Vol. 35 (4), pp. 1012-1022. Date of Electronic Publication: 2020 Aug 06.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

The roles of ATF2 (activating transcription factor 2) in tumorigenesis.

Authors: Gozdecka M Breitwieser W

Source: Biochemical Society transactions [Biochem Soc Trans] 2012 Feb; Vol. 40 (1), pp. 230-4.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

Journal Info: Publisher: Portland Press On The Behalf Of The Biochemical Society Country of Publication: England NLM ID: 7506897 Publication Model: Print Cited Medium: Internet ISSN: 1470-8752 (Electronic) Linking ISSN: 03005127 NLM ISO Abbreviation: Biochem Soc Trans Subsets: MEDLINE

Heme oxygenase-1 accelerates cutaneous wound healing in mice.

Authors: Grochot-Przeczek A Lach R Mis J et al.

Source: PloS one [PLoS One] 2009 Jun 04; Vol. 4 (6), pp. e5803. Date of Electronic Publication: 2009 Jun 04.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.

Authors: Basheer F Giotopoulos G Meduri E et al.

Source: The Journal of experimental medicine [J Exp Med] 2019 Apr 01; Vol. 216 (4), pp. 966-981. Date of Electronic Publication: 2019 Mar 19.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE

UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.

Authors: Gozdecka M Meduri E Mazan M et al.

Source: Nature genetics [Nat Genet] 2018 Jun; Vol. 50 (6), pp. 883-894. Date of Electronic Publication: 2018 May 07.

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE